Overview of Methods for Overcoming Hindrance to Drug Delivery to Tumors, with Special Attention to Tumor Interstitial Fluid Gianfranco Baronzio et al, 2015, Front. Oncol. CrossRef
Remodeling Components of the Tumor Microenvironment to Enhance Cancer Therapy Vasiliki Gkretsi et al, 2015, Front. Oncol. CrossRef
TRAIL, Wnt, Sonic Hedgehog, TGFβ, and miRNA Signalings Are Potential Targets for Oral Cancer Therapy Ammad Farooqi et al, 2017, IJMS CrossRef
Role of transforming growth factor-β1 in triple negative breast cancer patients Mingxia Zhang et al, 2017, International Journal of Surgery CrossRef
Physical oncology: New targets for nanomedicine Alba Nicolas-Boluda et al, 2018, Biomaterials CrossRef
Collateral Damage Intended—Cancer-Associated Fibroblasts and Vasculature Are Potential Targets in Cancer Therapy Ana Cavaco et al, 2017, IJMS CrossRef
TGFβ pathway inhibition in the treatment of non-small cell lung cancer Pınar Ö. Eser et al, 2017, Pharmacology & Therapeutics CrossRef
Toward Biological Subtyping of Papillary Renal Cell Carcinoma With Clinical Implications Through Histologic, Immunohistochemical, and Molecular Analysis Rola M. Saleeb et al, 2017, The American Journal of Surgical Pathology CrossRef
Nanoparticle-based hyperthermia, a local treatment modulating the tumor extracellular matrix Jelena Kolosnjaj-Tabi et al, 2017, Pharmacological Research CrossRef
Chinese medicine Bu-Fei decoction attenuates epithelial-mesenchymal transition of non-small cell lung cancer via inhibition of transforming growth factor β1 signaling pathway in vitro and in vivo Xi-Ran He et al, 2017, Journal of Ethnopharmacology CrossRef
Genetic status of KRAS influences Transforming Growth Factor-beta (TGF-β) signaling: an insight into Neuropilin-1 (NRP1) mediated tumorigenesis Sneha Vivekanandhan et al, 2018, Seminars in Cancer Biology CrossRef
Solid Stress Facilitates Fibroblasts Activation to Promote Pancreatic Cancer Cell Migration Maria Kalli et al, 2018, Ann Biomed Eng CrossRef
Adaptive immune cells are necessary for the enhanced therapeutic effect of sorafenib-loaded nanoparticles Zhi-Bin Zhao et al, 2018, Biomater. Sci. CrossRef
Transforming growth factor-β modulates pancreatic cancer associated fibroblasts cell shape, stiffness and invasion Andreas Stylianou et al, 2018, Biochimica et Biophysica Acta (BBA) - General Subjects CrossRef
Stress alleviation strategy in cancer treatment: Insights from a mathematical model Fotios Mpekris et al, 2018, Z. Angew. Math. Mech. CrossRef
A miRNA-145/TGF-β1 negative feedback loop regulates the cancer-associated fibroblast phenotype Genevieve E Melling et al, 2018 CrossRef
Effects of platelets on cancer progression Léa Plantureux et al, 2018, Thrombosis Research CrossRef
Cell Adhesion and Matrix Stiffness: Coordinating Cancer Cell Invasion and Metastasis Vasiliki Gkretsi et al, 2018, Front. Oncol. CrossRef
TGF-β1 induced fascin1 expression facilitates the migration and invasion of kidney carcinoma cells through ERK and JNK signaling pathways Jianyu Yang et al, 2018, Biochemical and Biophysical Research Communications CrossRef
Peroxiredoxin 6 inhibits osteogenic differentiation and bone formation through human dental pulp stem cells and induces delayed bone development Kyung-Ran Park et al, 2018, Antioxidants & Redox Signaling CrossRef
Sonic-hedgehog pathway inhibition normalizes desmoplastic tumor microenvironment to improve chemo- and nanotherapy Fotios Mpekris et al, 2017, Journal of Controlled Release CrossRef
Macrophage-Associated PGK1 Phosphorylation Promotes Aerobic Glycolysis and Tumorigenesis Yajuan Zhang et al, 2018, Molecular Cell CrossRef
Unveiling gene trait relationship by cross-platform meta-analysis on Chinese hamster ovary cell transcriptome Liang Zhao et al, 2017, Biotechnol. Bioeng. CrossRef
Signaling pathways and steroid receptors modulating estrogen receptor α function in breast cancer Rasmus Siersbæk et al, 2018, Genes Dev. CrossRef
Reengineering the Tumor Microenvironment to Alleviate Hypoxia and Overcome Cancer Heterogeneity John D. Martin et al, 2016, Cold Spring Harb Perspect Med CrossRef
Transforming growth factor β1-induced collagen production in myofibroblasts is mediated by reactive oxygen species derived from NADPH oxidase 4 Yuma Hotta et al, 2018, Biochemical and Biophysical Research Communications CrossRef
Novel Transforming Growth Factor-Beta Receptor 1 Antagonists through a Pharmacophore-Based Virtual Screening Approach Junhao Jiang et al, 2018, Molecules CrossRef
The Solid Mechanics of Cancer and Strategies for Improved Therapy. Triantafyllos Stylianopoulos, 0 CrossRef
Obstacles to T cell migration in the tumor microenvironment Alba Nicolas-Boluda et al, 2018, Comparative Immunology, Microbiology and Infectious Diseases CrossRef
A Longitudinal Study of the Association between Mammographic Density and Gene Expression in Normal Breast Tissue Helga Bergholtz et al, 2019, J Mammary Gland Biol Neoplasia CrossRef
TGF-β in Pancreatic Disease: Mechanisms and Therapeutic Potential Qi Zhou et al, 2019, Pharmacological Research CrossRef
Recent advances in understanding the roles of matrix metalloproteinases in tumour invasion and metastasis Guy A Conlon et al, 2019, J. Pathol. CrossRef
Dianthus superbus Improves Glomerular Fibrosis and Renal Dysfunction in Diabetic Nephropathy Model Jung Yoon et al, 2019, Nutrients CrossRef
Searching for the link; mechanisms underlying liver regeneration and recurrence of colorectal liver metastasis post partial hepatectomy Georgina E. Riddiough et al, 2019, Journal of Gastroenterology and Hepatology CrossRef
TGFB1-driven mesenchymal stem cell-mediated NIS gene transfer Christina Schug et al, 2019 CrossRef
Epithelial to Mesenchymal Transition and Cell Biology of Molecular Regulation in Endometrial Carcinogenesis. Hsiao-Chen Chiu et al, 2019, J Clin Med CrossRef
Anti-Müllerian Hormone Expression in Endometrial Cancer Tissue Marek Gowkielewicz et al, 2019, IJMS CrossRef
Combined Inhibition of TGF-β Signaling and the PD-L1 Immune Checkpoint Is Differentially Effective in Tumor Models Heng Sheng Sow et al, 2019, Cells CrossRef
Cancer-associated fibroblasts enact field cancerization by promoting extratumoral oxidative stress Jeremy Soon Kiat Chan et al, 2017, Cell Death Dis CrossRef
Tranilast-induced stress alleviation in solid tumors improves the efficacy of chemo- and nanotherapeutics in a size-independent manner Panagiotis Papageorgis et al, 2017, Sci Rep CrossRef
Collagen content and extracellular matrix cause cytoskeletal remodelling in pancreatic fibroblasts Andreas Stylianou et al, 2019, J. R. Soc. Interface CrossRef
Bone Metastasis Phenotype and Growth Undergo Regulation by Micro-Environment Stimuli: Efficacy of Early Therapy with HGF or TGFβ1-Type I Receptor Blockade Paola Bendinelli et al, 2019, IJMS CrossRef
Chimeric antigen receptors designed to overcome transforming growth factor-β-mediated repression in the adoptive T-cell therapy of solid tumors Jordan Hartley et al, 2019, Clin Transl Immunol CrossRef
Tumour-derived transforming growth factor-β signalling contributes to fibrosis in patients with cancer cachexia Joanna D.C.C. Lima et al, 2019, Journal of Cachexia, Sarcopenia and Muscle CrossRef
Integrated Molecular Analysis of Papillary Renal Cell Carcinoma and Precursor Lesions Unfolds Evolutionary Process from Kidney Progenitor-Like Cells Rola M. Saleeb et al, 2019, The American Journal of Pathology CrossRef
Reverse signaling by semaphorin 4C elicits SMAD1/5- and ID1/3-dependent invasive reprogramming in cancer cells Sreeharsha Gurrapu et al, 2019, Sci. Signal. CrossRef
Role of the Microenvironment in Regulating Normal and Cancer Stem Cell Activity: Implications for Breast Cancer Progression and Therapy Response Vasudeva Bhat et al, 2019, Cancers CrossRef
New insights into the functions of intersectin-1s Sanda Predescu et al, 2015, Communicative & Integrative Biology CrossRef
Discovery of New Inhibitors of Transforming Growth Factor-Beta Type 1 Receptor by Utilizing Docking and Structure-Activity Relationship Analysis null Jiang et al, 2019, IJMS CrossRef
ATP-binding cassette sub-family C member 4 (ABCC4) is overexpressed in human NK/T-cell lymphoma and regulates chemotherapy sensitivity: Potential as a functional therapeutic target Xudong Zhang et al, 2015, Leukemia Research CrossRef
Remodeling of extracellular matrix due to solid stress accumulation during tumor growth Athanassios P. Pirentis et al, 2015, Connective Tissue Research CrossRef
Tumor stromal disrupting agent enhances the anticancer efficacy of docetaxel loaded PEGylated liposomes in lung cancer Ketan Patel et al, 2016, Nanomedicine CrossRef
Profile of MMP and TIMP Expression in Human Pancreatic Stellate Cells: Regulation by IL-1α and TGFβ and Implications for Migration of Pancreatic Cancer Cells Vegard Tjomsland et al, 2016, Neoplasia CrossRef
TGF-ß alterations in oral squamous cell carcinoma. Narrative review Jorge Candia, 2016, J Oral Res CrossRef
Hyaluronan-Derived Swelling of Solid Tumors, the Contribution of Collagen and Cancer Cells, and Implications for Cancer Therapy Chrysovalantis Voutouri et al, 2016, Neoplasia CrossRef
EMT and inflammation: inseparable actors of cancer progression. Meggy Suarez-Carmona et al, 2017, Mol Oncol CrossRef
Silencing of TGF-β1 in tumor cells impacts MMP-9 in tumor microenvironment Lakisha D. Moore-Smith et al, 2017, Sci Rep CrossRef
Farnesol abrogates epithelial to mesenchymal transition process through regulating Akt/mTOR pathway Jong Hyun Lee et al, 2019, Pharmacological Research CrossRef
Thrombin contributes to cancer immune evasion via proteolysis of platelet-bound GARP to activate LTGF-β Alessandra Metelli et al, 2020, Sci. Transl. Med. CrossRef
Size-Tunable Strategies for a Tumor Targeted Drug Delivery System Wenqi Yu et al, 2020, ACS Cent. Sci. CrossRef
TGF-beta: a master immune regulator Christopher Larson et al, 2020, Expert Opinion on Therapeutic Targets CrossRef
Mechanisms of TGFβ3 Action as a Therapeutic Agent for Promoting the Synthesis of Extracellular Matrix Proteins in Hyaline Cartilage M. S. Bozhokin et al, 2020, Biochemistry Moscow CrossRef
Development of tissue factor-targeted liposomes for effective drug delivery to stroma-rich tumors Kosuke Shimizu et al, 2020, Journal of Controlled Release CrossRef
Mutation of TGFβ-RII eliminates NSAID cancer chemoprevention Juana Martín-López et al, 2018, Oncotarget CrossRef
Targeting hyaluronan accumulation in the tumor microenvironment Xiaoming Li et al, 2018, Oncotarget CrossRef
Pirfenidone normalizes the tumor microenvironment to improve chemotherapy Christiana Polydorou et al, 2017, Oncotarget CrossRef
STIM1 plays an important role in TGF-β-induced suppression of breast cancer cell proliferation Huanyi Cheng et al, 2016, Oncotarget CrossRef
Nestin suppression attenuates invasive potential of endometrial cancer cells by downregulating TGF-β signaling pathway Amber A. Bokhari et al, 2016, Oncotarget CrossRef
Novel Medicinal Mushroom Blend as a Promising Supplement in Integrative Oncology: A Multi-Tiered Study using 4T1 Triple-Negative Mouse Breast Cancer Model Elisa Roda et al, 2020, IJMS CrossRef
The Role of Tumor-Associated Myeloid Cells in Modulating Cancer Therapy Christiana M. Neophytou et al, 2020, Front. Oncol. CrossRef
Clinical and genomic landscape of hepatocellular carcinoma subtypes with various proportions of nonleukocyte stromal cells Jie Peng et al, 2020, Gene CrossRef
Co-inhibition of the TGF-β pathway and the PD-L1 checkpoint by pH-responsive clustered nanoparticles for pancreatic cancer microenvironment regulation and anti-tumor immunotherapy Yang Wang et al, 2020, Biomater. Sci. CrossRef
Porphyromonas gingivalis promotes progression of esophageal squamous cell cancer via TGFβ-dependent Smad/YAP/TAZ signaling Yi-Jun Qi et al, 2020, PLoS Biol CrossRef
The Tumor Suppressor TGFBR3 Blocks Lymph Node Metastasis in Head and Neck Cancer Wei-Yu Fang et al, 2020, Cancers CrossRef
The Current Landscape of Immune Checkpoint Blockade in Hepatocellular Carcinoma: A Review. Matthias Pinter et al, 2021, JAMA Oncol CrossRef
Angiotensin Inhibition, TGF-β and EMT in Cancer. Fabian Bernhard Pallasch et al, 2020, Cancers (Basel) CrossRef
Remodeling of the Collagen Matrix in Aging Skin Promotes Melanoma Metastasis and Affects Immune Cell Motility Amanpreet Kaur et al, 2019, Cancer Discov CrossRef
Something Old, Something New: The Tumor Microenvironment Comes of Age Kerrie L. Marie et al, 2019, Cancer Discov CrossRef
Annexin A1 Released in Extracellular Vesicles by Pancreatic Cancer Cells Activates Components of the Tumor Microenvironment, through Interaction with the Formyl-Peptide Receptors. Nunzia Novizio et al, 2020, Cells CrossRef
Radiation-Induced Amplification of TGFB1-Induced Mesenchymal Stem Cell–Mediated Sodium Iodide Symporter (NIS) Gene 131I Therapy Christina Schug et al, 2019, Clin Cancer Res CrossRef
Myeloid Cell–Derived TGFβ Signaling Regulates ECM Deposition in Mammary Carcinoma via Adenosine-Dependent Mechanisms Georgii Vasiukov et al, 2020, Cancer Res CrossRef
Role of Platelet-Derived Tgfβ1 in the Progression of Ovarian Cancer Qianghua Hu et al, 2017, Clin Cancer Res CrossRef
Immunotherapy and Targeted Therapy for Hepatocellular Carcinoma: A Literature Review and Treatment Perspectives Daniel M. Girardi et al, 2020, Pharmaceuticals CrossRef
Prognostic significance of transforming growth factor β receptor II in clinical stage III breast cancer patients - a pilot study Sherif Refaat et al, 2021, BD CrossRef
TGFβ signaling networks in ovarian cancer progression and plasticity Asha Kumari et al, 2021, Clin Exp Metastasis CrossRef
The Tumor Microenvironment Impairs Th1 IFNγ Secretion through Alternative Splicing Modifications of Irf1 Pre-mRNA Antoine Bernard et al, 2021, Cancer Immunol Res CrossRef
Cancer-associated cells release citrate to support tumour metastatic progression Konstantin Drexler et al, 2021, Life Sci. Alliance CrossRef
Characterization of the Immune Cell Infiltration Profile in Pancreatic Carcinoma to Aid in Immunotherapy De Luo et al, 2021, Front. Oncol. CrossRef
Self-driving armored CAR-T cells overcome a suppressive milieu and eradicate CD19+ Raji lymphoma in preclinical models Brian Webster et al, 2021, Molecular Therapy CrossRef
Gene Expression Analysis Provides New Insights into the Mechanism of Intramuscular Fat Formation in Japanese Black Cattle Shuji Ueda et al, 2021, Genes CrossRef
Pancreatic Adenocarcinoma Therapeutics Targeting RTK and TGF Beta Receptor Hsin-Han Yang et al, 2021, IJMS CrossRef
Blood levels of growth and progression factors in patients with locally advanced breast cancer during neoadjuvant chemotherapy E. M. Frantsiyants et al, 2021, jour CrossRef
Optimization strategies for expression of a novel bifunctional anti-PD-L1/TGFBR2-ECD fusion protein Zhang-zhao Gao et al, 2022, Protein Expression and Purification CrossRef
ANXA1 Contained in EVs Regulates Macrophage Polarization in Tumor Microenvironment and Promotes Pancreatic Cancer Progression and Metastasis Nunzia Novizio et al, 2021, IJMS CrossRef
Impact of a Desmoplastic Tumor Microenvironment for Colon Cancer Drug Sensitivity: A Study with 3D Chimeric Tumor Spheroids Venkanagouda S. Goudar et al, 2021, ACS Appl. Mater. Interfaces CrossRef
Stromal disruption facilitating invasion of a ‘nano-arsenal’ into the solid tumor Yige Fu et al, 2021, Drug Discovery Today CrossRef
TGF-β1 and its signal molecules: are they correlated with the elasticity characteristics of breast lesions? Meng Ke Zhang et al, 2021, BMC Cancer CrossRef
Therapeutic Potential of Thymoquinone in Triple-Negative Breast Cancer Prevention and Progression through the Modulation of the Tumor Microenvironment. Karam Soliman, 0 CrossRef
Association of SMAD7 genetic markers and haplotypes with colorectal cancer risk Maryam Alidoust et al, 2022, BMC Med Genomics CrossRef
Inflammation and Myeloid Cells in Cancer Progression and Metastasis Jenying Deng et al, 2022, Front. Cell Dev. Biol. CrossRef
Exosomes derived from γδ-T cells synergize with radiotherapy and preserve antitumor activities against nasopharyngeal carcinoma in immunosuppressive microenvironment Xiwei Wang et al, 2022, J Immunother Cancer CrossRef
Tumor microenvironment-responsive size-switchable drug delivery nanosystems Yue Hu et al, 2022, Expert Opinion on Drug Delivery CrossRef
Synergistic checkpoint-blockade and radiotherapy–radiodynamic therapy via an immunomodulatory nanoscale metal–organic framework Kaiyuan Ni et al, 2022, Nat Biomed Eng CrossRef
Polymeric Systems for Cancer Immunotherapy: A Review Thai Minh Duy Le et al, 2022, Front. Immunol. CrossRef
Integrins and Epithelial-Mesenchymal Cooperation in the Tumor Microenvironment of Muscle-Invasive Lethal Cancers William L. Harryman et al, 2022, Front. Cell Dev. Biol. CrossRef
Modeling the Mechanical Stiffness of Pancreatic Ductal Adenocarcinoma Delanyo Kpeglo et al, 2022, Matrix Biology Plus CrossRef
The solid tumor microenvironment—Breaking the barrier for T cells Hasan Simsek et al, 2022, BioEssays CrossRef
Targeting the Tumor Biophysical Microenvironment to Reduce Resistance to Immunotherapy Tian Zhang et al, 2022, Advanced Drug Delivery Reviews CrossRef
TGF-β1 induced autophagy in cancer associated fibroblasts during hypoxia contributes EMT and glycolysis via MCT4 upregulation Bikash Chandra Jena et al, 2022, Experimental Cell Research CrossRef
Targeting Soluble Factors Involved in Inflammatory Cancer Microenvironment M. Gayathri et al, 2022, Curr Pharmacol Rep CrossRef
Shaping the “hot” immunogenic tumor microenvironment by nanoparticles co‐delivering oncolytic peptide and
TGF
‐β1
siRNA
for boosting checkpoint blockade therapy
Cao Dai Phung et al, 2022, Bioengineering & Transla Med CrossRef
Transforming Growth Factor-Beta Signaling in Cancer-Induced Cachexia: From Molecular Pathways to the Clinics Rita Balsano et al, 2022, Cells CrossRef
TGF-β1 upregulates Sar1a expression and induces procollagen-I secretion in hypertrophic scarring fibroblasts Keun Jae Ahn et al, 2022 CrossRef
A novel cell-based assay for the high-throughput screening of epithelial–mesenchymal transition inhibitors: Identification of approved and investigational drugs that inhibit epithelial–mesenchymal transition Hiroyuki Ishikawa et al, 2022, Lung Cancer CrossRef
Dickkopf-3: An Update on a Potential Regulator of the Tumor Microenvironment Zainab Al Shareef et al, 2022, Cancers CrossRef
Mechanism of Extracellular Vesicle Secretion Associated with TGF-β-Dependent Inflammatory Response in the Tumor Microenvironment Klaudia Bonowicz et al, 2022, IJMS CrossRef