1. Design, synthesis and pharmaco-toxicological assessment of 5-mercapto-1,2,4-triazole derivatives with antibacterial and antiproliferative activity
    Marius Mioc et al, 2017 CrossRef
  2. Isofraxidin inhibited proliferation and induced apoptosis via blockage of Akt pathway in human colorectal cancer cells
    Peng Shen et al, 2017, Biomedicine & Pharmacotherapy CrossRef
  3. TAp73 is a marker of glutamine addiction in medulloblastoma
    Maria Victoria Niklison-Chirou et al, 2017, Genes Dev. CrossRef
  4. Reverse Nearest Neighbor Search on a Protein-Protein Interaction Network to Infer Protein-Disease Associations
    Apichat Suratanee et al, 2017, Bioinformatics and Biology Insights CrossRef
  5. Testicular orphan receptor 4 promotes tumor progression and implies poor survival through AKT3 regulation in seminoma
    Yuanlei Chen et al, 2018, Cancer Sci CrossRef
  6. Contributions of Thyroid Hormone to Cancer Metastasis
    Shaker Mousa et al, 2018, Biomedicines CrossRef
  7. miR-377-5p inhibits lung cancer cell proliferation, invasion, and cell cycle progression by targeting AKT1 signaling
    Han Wu et al, 2018, J Cell Biochem CrossRef
  8. Cyclin‐dependent kinase 9 promotes cervical cancer development via AKT2/p53 pathway
    Junfen Xu et al, 2018, IUBMB Life CrossRef
  9. Clinical significance of multiple gene detection with a 22-gene panel in formalin-fixed paraffin-embedded specimens of 207 colorectal cancer patients
    Xian Hua Gao et al, 2019, Int J Clin Oncol CrossRef
  10. AKT2 phosphorylation of hexokinase 2 at T473 promotes tumorigenesis and metastasis in colon cancer cells via NF-κB, HIF1α, MMP2, and MMP9 upregulation
    Hang Li et al, 2019, Cellular Signalling CrossRef
  11. Anti-inflammatory functions of the CDC25 phosphatase inhibitor BN82002 via targeting AKT2
    Han Gyung Kim et al, 2019, Biochemical Pharmacology CrossRef
  12. C-Reactive Protein Promotes Inflammation through FcγR-Induced Glycolytic Reprogramming of Human Macrophages
    Melissa Newling et al, 2019, J.I. CrossRef
  13. Inhibition of the Numb/Notch signaling pathway increases radiation sensitivity in human nasopharyngeal carcinoma cells
    Er‐Dong Shen et al, 2019, The Kaohsiung Journal of Medical Sciences CrossRef
  14. Isoform-Specific Role of Akt in Oral Squamous Cell Carcinoma
    null Roy et al, 2019, Biomolecules CrossRef
  15. Distinct functions of AKT isoforms in breast cancer: a comprehensive review
    Nico Hinz et al, 2019, Cell Commun Signal CrossRef
  16. Depletion of Akt1 and Akt2 Impairs the Repair of Radiation-Induced DNA Double Strand Breaks via Homologous Recombination
    Tahereh Mohammadian Gol et al, 2019, IJMS CrossRef
  17. β-elemene suppresses the malignant behavior of esophageal cancer cells by regulating the phosphorylation of AKT
    Yufei Liang et al, 2020, Acta Histochemica CrossRef
  18. Differential gene expression and AKT targeting in triple negative breast cancer
    Feng-Mao Lin et al, 2019, Oncotarget CrossRef
  19. Bioinformatics analysis integrating metabolomics of m6A RNA microarray in intervertebral disc degeneration
    Xiaoshuai Wang et al, 2020, Epigenomics CrossRef
  20. GLUT5 regulation by AKT1/3-miR-125b-5p downregulation induces migratory activity and drug resistance in TLR-modified colorectal cancer cells
    Ga-Bin Park et al, 2020 CrossRef
  21. UDP-glucose 6-dehydrogenase knockout impairs migration and decreases in vivo metastatic ability of breast cancer cells
    Shao Thing Teoh et al, 2020, Cancer Letters CrossRef
  22. High Sensitivity of Circulating Tumor Cells Derived from a Colorectal Cancer Patient for Dual Inhibition with AKT and mTOR Inhibitors
    Daniel J. Smit et al, 2020, Cells CrossRef
  23. Bioinformatic analysis of CCA-1.1, a novel curcumin analog, uncovers furthermost noticeable target genes in colon cancer
    Febri Wulandari et al, 2020, Gene Reports CrossRef
  24. Cytochrome C Oxidase Assembly Factor 1 Homolog Predicts Poor Prognosis and Promotes Cell Proliferation in Colorectal Cancer by Regulating PI3K/AKT Signaling


    Yuan Xue et al, 2020, OTT CrossRef
  25. Deletion of Akt1 Promotes Kidney Fibrosis in a Murine Model of Unilateral Ureteral Obstruction
    Il Young Kim et al, 2020, BioMed Research International CrossRef
  26. Nongenomic Actions of Thyroid Hormone: The Integrin Component
    Paul J. Davis et al, 2021, Physiological Reviews CrossRef
  27. Mechanism of Fuzilizhong Decoction on the Treatment of Ulcerative Colitis by Network Pharmacology
    艺 杨, 2021, TCM CrossRef
  28. Integrated Network Pharmacology Analysis and In Vitro Validation Revealed the Potential Active Components and Underlying Mechanistic Pathways of Herba Patriniae in Colorectal Cancer
    Huihai Yang et al, 2021, Molecules CrossRef
  29. NEBL and AKT1 maybe new targets to eliminate the colorectal cancer cells resistance to oncolytic effect of vesicular stomatitis virus M-protein
    Zoleikha Mamizadeh et al, 2021, Molecular Therapy - Oncolytics CrossRef
  30. In Vivo and In Vitro Enhanced Tumoricidal Effects of Metformin, Active Vitamin D3, and 5-Fluorouracil Triple Therapy against Colon Cancer by Modulating the PI3K/Akt/PTEN/mTOR Network
    Riyad Adnan Almaimani et al, 2022, Cancers CrossRef
  31. Ozone exposure and blood transcriptome: a randomized, controlled, crossover trial among healthy adults
    Xihao Du et al, 2022, Environment International CrossRef
  32. Bioactive Components and Potential Mechanism Prediction of Kui Jie Kang against Ulcerative Colitis via Systematic Pharmacology and UPLC-QE-MS Analysis
    Jinbiao He et al, 2022, Evidence-Based Complementary and Alternative Medicine CrossRef
  33. Mechanism of Danhong Injection in the Treatment of Arrhythmia Based on Network Pharmacology, Molecular Docking, and In Vitro Experiments
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  34. Study on the Mechanism of Xiaotan Sanjie Recipe in the Treatment of Colon Cancer Based on Network Pharmacology
    Xiao-wei Wang et al, 2022, BioMed Research International CrossRef
  35. Electroacupuncture improves TBI dysfunction by targeting HDAC overexpression and BDNF-associated Akt/GSK-3β signaling
    Shih-Ya Hung et al, 2022, Front. Cell. Neurosci. CrossRef
  36. Identification and development of a subtype-selective allosteric AKT inhibitor suitable for clinical development.
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  37. Network pharmacology-based analysis of the mechanism of Guben Sanjie Pill in the treatment of lung cancer
    Kai Wang et al, 2022, Journal of Herbal Medicine CrossRef
  38. Crosstalk between circRNAs and the PI3K/AKT signaling pathway in cancer progression
    Chen Xue et al, 2021, Sig Transduct Target Ther CrossRef
  39. A Network-Pharmacology-Combined Integrated Pharmacokinetic Strategy to Investigate the Mechanism of Potential Liver Injury due to Polygonum multiflorum
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  40. Mechanism of andrographis paniculata on lung cancer by network pharmacology and molecular docking
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  41. Nanotechnology-empowered lung cancer therapy: From EMT role in cancer metastasis to application of nanoengineered structures for modulating growth and metastasis
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    Sergio Antonio Oropeza-de Lara et al, 2023, Cancers CrossRef
  43. Lysicamine Reduces Protein Kinase B (AKT) Activation and Promotes Necrosis in Anaplastic Thyroid Cancer
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  44. Class IA PI3K isoforms lead to differential signalling downstream of PKB/Akt
    Hazal B. Catalak Yilmaz et al, 2023 CrossRef
  45. Dendrobium huoshanense in the treatment of ulcerative colitis: Network pharmacology and experimental validation
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  46. Research on the Regulatory Mechanism of Ginseng on the Tumor Microenvironment of Colorectal Cancer based on Network Pharmacology and Bioinformatics Validation
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  47. Regulatory effects of statins on Akt signaling for prevention of cancers
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