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    Cécile Cumin et al, 2021, Biomolecules CrossRef
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  3. PD-L1 Blockade by Atezolizumab Downregulates Signaling Pathways Associated with Tumor Growth, Metastasis, and Hypoxia in Human Triple Negative Breast Cancer
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  4. KLHL18 inhibits the proliferation, migration, and invasion of non-small cell lung cancer by inhibiting PI3K/PD-L1 axis activity
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  5. Targeting the phosphoinositide-3-kinase/protein kinase B pathway in airway innate immunity
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  6. Vav1 Down-Modulates Akt2 Expression in Cells from Pancreatic Ductal Adenocarcinoma: Nuclear Vav1 as a Potential Regulator of Akt Related Malignancy in Pancreatic Cancer
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  7. Characterization of the in vitro cytotoxic effects of brachydins isolated from Fridericia platyphylla in a prostate cancer cell line
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  8. Rosemary Extract Inhibits Proliferation, Survival, Akt, and mTOR Signaling in Triple-Negative Breast Cancer Cells
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  9. Aldo-Keto Reductase 1C3 Mediates Chemotherapy Resistance in Esophageal Adenocarcinoma via ROS Detoxification
    Chenghui Zhou et al, 2021, Cancers CrossRef
  10. Fuzheng Jiedu Xiaoji formulation inhibits hepatocellular carcinoma progression in patients by targeting the AKT/CyclinD1/p21/p27 pathway
    Xue Yang et al, 2021, Phytomedicine CrossRef
  11. Akt phosphorylates insulin receptor substrate to limit PI3K-mediated PIP3 synthesis
    Alison L Kearney et al, 2021, eLife CrossRef
  12. OSU-03012 Disrupts Akt Signaling and Prevents Endometrial Carcinoma Progression in vitro and in vivo
    Leilei Ding et al, 2021, Drug Design, Development and Therapy CrossRef
  13. In Silico Screening Anticancer of Six Triterpenoids toward miR-494 and TNF-α Targets
    Vikra Ardiansyah Zaini et al, 2020, Jurnal Kimia Sains dan Aplikasi CrossRef
  14. Insights into Mechanisms of Tumorigenesis in Neuroendocrine Neoplasms
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  15. The Anti-Cancer Effect of Quercetin: Molecular Implications in Cancer Metabolism
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  16. Regulation of Autophagy by Non-Steroidal Anti-Inflammatory Drugs in Cancer


    Xiangjie Fu et al, 2020, Cancer Management and Research CrossRef
  17. Ginsenoside Rh1 Induces MCF-7 Cell Apoptosis and Autophagic Cell Death through ROS-Mediated Akt Signaling
    Diem Thi Ngoc Huynh et al, 2021, Cancers CrossRef
  18. Methionine Supplementation Affects Metabolism and Reduces Tumor Aggressiveness in Liver Cancer Cells
    Farida Tripodi et al, 2020, Cells CrossRef
  19. Mechanisms of Resistance to PI3K Inhibitors in Cancer: Adaptive Responses, Drug Tolerance and Cellular Plasticity
    Sarah Christine Elisabeth Wright et al, 2021, Cancers CrossRef
  20. Preclinical Efficacy and Involvement of AKT, mTOR, and ERK Kinases in the Mechanism of Sulforaphane against Endometrial Cancer
    Rajani Rai et al, 2020, Cancers CrossRef
  21. Onosma bracteata Wall. induces G0/G1 arrest and apoptosis in MG-63 human osteosarcoma cells via ROS generation and AKT/GSK3β/cyclin E pathway
    Ajay Kumar et al, 2021, Environmental Science and Pollution Research CrossRef
  22. Feedback, Crosstalk and Competition: Ingredients for Emergent Non-Linear Behaviour in the PI3K/mTOR Signalling Network
    Milad Ghomlaghi et al, 2021, International Journal of Molecular Sciences CrossRef
  23. Integrated Analysis of Genomic and Immunological Features in Lung Adenocarcinoma With Micropapillary Component
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  24. Isolation and Establishment of a Highly Proliferative, Cancer Stem Cell-Like, and Naturally Immortalized Triple-Negative Breast Cancer Cell Line, KAIMRC2
    Rizwan Ali et al, 2021, Cells CrossRef
  25. In Depth Analysis of Kinase Cross Screening Data to Identify CAMKK2 Inhibitory Scaffolds
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  26. Inhibition of PI3K Isoform p110γ Increases Both Anti-Tumor and Immunosuppressive Responses to Aggressive Murine Head and Neck Squamous Cell Carcinoma with Low Immunogenicity
    Kelvin Anderson et al, 2021, Cancers CrossRef
  27. AKT Inhibitors: The Road Ahead to Computational Modeling-Guided Discovery
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  28. Inhibitors of the PI3K/Akt/mTOR Pathway in Prostate Cancer Chemoprevention and Intervention
    Nazanin Momeni Roudsari et al, 2021, Pharmaceutics CrossRef
  29. The Green Anti-Cancer Weapon. The Role of Natural Compounds in Bladder Cancer Treatment
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  30. Spotlight on AKT: Current Therapeutic Challenges
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  31. Recent Updates on the Involvement of PI3K/AKT/mTOR Molecular Cascade in the Pathogenesis of Hyperproliferative Skin Disorders
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  32. Phase 1 Dose Escalation Study of the Allosteric AKT Inhibitor BAY 1125976 in Advanced Solid Cancer—Lack of Association between Activating AKT Mutation and AKT Inhibition-Derived Efficacy
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  33. Targeting PI3K/AKT/mTOR Signaling Pathway in Breast Cancer
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  34. Kir4.1 may represent a novel therapeutic target for diabetic retinopathy (Review)
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