- Beauvericin inhibits melanogenesis by regulating cAMP/PKA/CREB and LXR-α/p38 MAPK–mediated pathways
Seung Eun Lee et al, 2018, Scientific Reports CrossRef - Alteration in bile acids profile in Large White pigs during chronic heat exposure
Wei Fang et al, 2019, Journal of Thermal Biology CrossRef - 27-Hydroxycholesterol Impairs Plasma Membrane Lipid Raft Signaling as Evidenced by Inhibition of IL6–JAK–STAT3 Signaling in Prostate Cancer Cells
Shweta Dambal et al, 2020, Molecular Cancer Research CrossRef - Identification of Side Chain Oxidized Sterols as Novel Liver X Receptor Agonists with Therapeutic Potential in the Treatment of Cardiovascular and Neurodegenerative Diseases
Na Zhan et al, 2023, International Journal of Molecular Sciences CrossRef - Synthesis and initial biological evaluation of new mimics of the LXR-modulator 22(S)-hydroxycholesterol
O. Alexander H. Åstrand et al, 2014, Bioorganic & Medicinal Chemistry CrossRef - Liver X receptor β activation induces pyroptosis of human and murine colon cancer cells
V Derangère et al, 2014, Cell Death & Differentiation CrossRef - Disorders of Cholesterol Metabolism and Their Unanticipated Convergent Mechanisms of Disease
Frances M. Platt et al, 2014, Annual Review of Genomics and Human Genetics CrossRef - The formation of giant plasma membrane vesicles enable new insights into the regulation of cholesterol efflux
Alanna Sedgwick et al, 2018, Experimental Cell Research CrossRef - Dihydrotanshinone Attenuates LPS-Induced Acute Lung Injury in Mice by Upregulating LXRα
Jing Yue et al, 2022, Inflammation CrossRef - Role of Brain Liver X Receptor in Parkinson’s Disease: Hidden Treasure and Emerging Opportunities
Saud A. Alnaaim et al, 2024, Molecular Neurobiology CrossRef - DSS-induced colitis is associated with adipose tissue dysfunction and disrupted hepatic lipid metabolism leading to hepatosteatosis and dyslipidemia in mice
Jeonghyeon Kwon et al, 2021, Scientific Reports CrossRef - Skeletal muscle insulin resistance in hamsters with diabetes developed from obesity is involved in abnormal skeletal muscle LXR, PPAR and SREBP expression
GUO-SHENG LI et al, 2016, Experimental and Therapeutic Medicine CrossRef - Kupffer cells: increasingly significant role in nonalcoholic fatty liver disease
Zhang Wenfeng et al, 2014, Annals of Hepatology CrossRef - Photodynamic Therapy and Cardiovascular Diseases
Aleksander Oskroba et al, 2024, International Journal of Molecular Sciences CrossRef - The effects of statin therapy on brain tumors, particularly glioma: a review
Amjad Z. Alrosan et al, 2023, Anti-Cancer Drugs CrossRef - Key role for lipids in cognitive symptoms of schizophrenia
Dorien A. Maas et al, 2020, Translational Psychiatry CrossRef - Central nervous system cholesterol metabolism in health and disease
Wan Y. Ho et al, 2022, IUBMB Life CrossRef - Molecular mechanisms underlying effects of n−3 and n−6 fatty acids in cardiovascular diseases
Denny Joseph Manual Kollareth et al, 2020, Lipid Signaling and Metabolism CrossRef - High Glucose Induces Lipid Accumulation via 25-Hydroxycholesterol DNA-CpG Methylation
Yaping Wang et al, 2020, iScience CrossRef - Pathway deregulation and expression QTLs in response to Actinobacillus pleuropneumoniae infection in swine
Gerald Reiner et al, 2014, Mammalian Genome CrossRef - Contribution of 25-hydroxycholesterol to the cross-interaction of the immune and nervous systems
Guzalia F. Zakyrjanova et al, 2023, Genes & Cells CrossRef - LXR agonist modifies neuronal lipid homeostasis and decreases PGD2 in the dorsal root ganglia in western diet-fed mice
Nadia Elshareif et al, 2022, Scientific Reports CrossRef - Hepatocyte activity of the cholesterol sensor smoothened regulates cholesterol and bile acid homeostasis in mice
George D. Dalton et al, 2021, iScience CrossRef - LXRα Regulates ChREBPα Transactivity in a Target Gene-Specific Manner through an Agonist-Modulated LBD-LID Interaction
Qiong Fan et al, 2020, Cells CrossRef - Phytotherapy for Cardiovascular Disease: A Bench-to-Bedside Approach
Mervin Chávez-Castillo et al, 2020, Current Pharmaceutical Design CrossRef - Lipid Metabolism Disorders in the Comorbid Course of Nonalcoholic Fatty Liver Disease and Chronic Obstructive Pulmonary Disease
Stanislav Kotlyarov et al, 2021, Cells CrossRef - Low‐Density Lipoproteins, High‐Density Lipoproteins (HDL), and HDL‐Associated Proteins Differentially Modulate Chronic Myelogenous Leukemia Cell Viability
Catherine J. Andersen et al, 2020, Lipids CrossRef - Cholesterol Metabolites 25-Hydroxycholesterol and 25-Hydroxycholesterol 3-Sulfate Are Potent Paired Regulators: From Discovery to Clinical Usage
Yaping Wang et al, 2020, Metabolites CrossRef - Oxidative stress-related gene expression in diploid and triploid rainbow trout (Oncorhynchus mykiss) fed diets with organic and inorganic zinc
Kristen A. Meiler et al, 2021, Aquaculture CrossRef - Defining a vitamin A5/X specific deficiency – vitamin A5/X as a critical dietary factor for mental health
Diána Bánáti et al, 2024, International Journal for Vitamin and Nutrition Research CrossRef - Combined LXR and RXR Agonist Therapy Increases ABCA1 Protein Expression and Enhances ApoAI-Mediated Cholesterol Efflux in Cultured Endothelial Cells
Kun Huang et al, 2021, Metabolites CrossRef - Genetic Risk Factors
Marc Thiriet, 2018, Vasculopathies CrossRef - The effect of maternal undernutrition on the rat placental transcriptome: protein restriction up-regulates cholesterol transport
Zoe Daniel et al, 2016, Genes & Nutrition CrossRef - Delineating the role of nuclear receptors in colorectal cancer, a focused review
Mukesh Kumar Manickasamy et al, 2024, Discover Oncology CrossRef - Purple perilla extracts with α-asarone enhance cholesterol efflux from oxidized LDL-exposed macrophages
SIN-HYE PARK et al, 2015, International Journal of Molecular Medicine CrossRef - Increased cholesterol synthesis drives neurotoxicity in patient stem cell-derived model of multiple sclerosis
Rosana-Bristena Ionescu et al, 2024, Cell Stem Cell CrossRef - The detrimental effect of asymmetric dimethylarginine on cholesterol efflux of macrophage foam cells: Role of the NOX/ROS signaling
Chia-Hui Chen et al, 2019, Free Radical Biology and Medicine CrossRef - Differences between the Molecular Mechanisms Underlying Ruptured and Non-Ruptured Carotid Plaques, and the Significance of ABCA1
Sung Hyuk Heo et al, 2018, Journal of Stroke CrossRef - LXRα represses LPS-induced inflammatory responses by competing with IRF3 for GRIP1 in Kupffer cells
Chun-mu Miao et al, 2016, International Immunopharmacology CrossRef - Cholesterol Transport Dysfunction and Its Involvement in Atherogenesis
Anastasia V. Poznyak et al, 2022, International Journal of Molecular Sciences CrossRef - Remembering your A, B, C's: Alzheimer's disease and ABCA1
Cutler T. Lewandowski et al, 2022, Acta Pharmaceutica Sinica B CrossRef - Pretreatment of hydroethanolic extract of Dillenia indica L. attenuates oleic acid induced NAFLD in HepG2 cells via modulating SIRT-1/p-LKB-1/AMPK, HMGCR & PPAR-α signaling pathways
M.S. Poornima et al, 2022, Journal of Ethnopharmacology CrossRef - Analysis of rare genetic variation underlying cardiometabolic diseases and traits among 200,000 individuals in the UK Biobank
Sean J. Jurgens et al, 2022, Nature Genetics CrossRef - Cholesterol in Pancreatic β-Cell Death and Dysfunction
Rajib Paul et al, 2016, Pancreas CrossRef - RORγ is a context-specific master regulator of cholesterol biosynthesis and an emerging therapeutic target in cancer and autoimmune diseases
Hongye Zou et al, 2022, Biochemical Pharmacology CrossRef - ASGR1 Deficiency Inhibits Atherosclerosis in Western Diet–Fed ApoE −/− Mice by Regulating Lipoprotein Metabolism and Promoting Cholesterol Efflux
Yuyan Zhang et al, 2024, Arteriosclerosis, Thrombosis, and Vascular Biology CrossRef - Pharmacological effects of Chinese medicine modulating NLRP3 inflammasomes in fatty liver treatment
Tingting Liu et al, 2022, Frontiers in Pharmacology CrossRef - Endoplasmic Reticulum Stress and Its Impact on Adipogenesis: Molecular Mechanisms Implicated
Gyuhui Kim et al, 2023, Nutrients CrossRef - Crystal structure of (S)-2-[(3S,8S,9S,10R,13S,14S,17R)-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]-N-methoxy-N-methylpropanamide (Fernholz Weinreb amide)
Elvar Ørn Viktorsson et al, 2015, Acta Crystallographica Section E Crystallographic Communications CrossRef - The Flavone Luteolin Inhibits Liver X Receptor Activation
Vera Francisco et al, 2016, Journal of Natural Products CrossRef - Efflux inhibition by H2S confers sensitivity to doxorubicin-induced cell death in liver cancer cells
Eric Stokes et al, 2018, Life Sciences CrossRef - Normocaloric Low Cholesterol Diet Modulates Th17/Treg Balance in Patients with Chronic Hepatitis C Virus Infection
Roberta Maggio et al, 2014, PLoS ONE CrossRef - Proteomic snapshot of saliva samples predicts new pathways implicated in SARS-CoV-2 pathogenesis
Elena Moreno et al, 2024, Clinical Proteomics CrossRef - Cholesterol and male fertility: What about orphans and adopted?
Salwan Maqdasy et al, 2013, Molecular and Cellular Endocrinology CrossRef - Cholesterol dyshomeostasis in amyotrophic lateral sclerosis: cause, consequence, or epiphenomenon?
Hannelore Hartmann et al, 2022, The FEBS Journal CrossRef - Effect of Siegesbeckia glabrescens Extract on Foam Cell Formation in THP-1 Macrophages
Ha-Rin Moon et al, 2024, Preventive Nutrition and Food Science CrossRef - Liver X receptors and skeleton: Current state-of-knowledge
Divya Goel et al, 2021, Bone CrossRef - Administration of an LXR agonist promotes atherosclerotic lesion remodelling in murine inflammatory arthritis
Dragana Dragoljevic et al, 2023, Clinical & Translational Immunology CrossRef