- Indoleamine 2,3-dioxygenase, by degrading L-tryptophan, enhances carnitine palmitoyltransferase I activity and fatty acid oxidation, and exerts fatty acid-dependent effects in human alloreactive CD4+ T-cells
Theodoros Eleftheriadis et al, 2016, International Journal of Molecular Medicine CrossRef - IDO/kynurenine pathway in cancer: possible therapeutic approaches
Eslam E. Abd El-Fattah, 2022, Journal of Translational Medicine CrossRef - Indoleamine 2,3-dioxygenase regulates T cell activity through Vav1/Rac pathway
Runmei Li et al, 2017, Molecular Immunology CrossRef - Control of T-Cell Activation and Signaling by Amino-Acid Catabolizing Enzymes
Flavia Castellano et al, 2020, Frontiers in Cell and Developmental Biology CrossRef - Kynurenine pathway in Coronavirus disease (COVID‐19): Potential role in prognosis
Murat Cihan et al, 2022, Journal of Clinical Laboratory Analysis CrossRef - What May Constrain the Success of Indoleamine 2,3-Dioxygenase 1 Inhibitors in Cancer Immunotherapy?
Theodoros Eleftheriadis, 2018, Frontiers in Immunology CrossRef - The Kynurenine Pathway—New Linkage between Innate and Adaptive Immunity in Autoimmune Endocrinopathies
Anna Krupa et al, 2021, International Journal of Molecular Sciences CrossRef - The potential role of T-cell metabolism-related molecules in chronic neuropathic pain after nerve injury: a narrative review
Xiaoke Dou et al, 2023, Frontiers in Immunology CrossRef - Survival of lymphocytes is not restricted by IDO-expressing fibroblast from rheumatoid arthritis patients
Magdalena Massalska et al, 2019, Immunopharmacology and Immunotoxicology CrossRef - IDO decreases glycolysis and glutaminolysis by activating GCN2K, while it increases fatty acid oxidation by activating AhR, thus preserving CD4+ T‑cell survival and proliferation
Theodoros Eleftheriadis et al, 2018, International Journal of Molecular Medicine CrossRef - The Role of Indoleamine 2, 3-Dioxygenase 1 in Regulating Tumor Microenvironment
Xinting Huang et al, 2022, Cancers CrossRef - Modulation of immune cell function, IDO expression and kynurenine production by the quorum sensor 2-heptyl-3-hydroxy-4-quinolone (PQS)
Joy Ogbechi et al, 2022, Frontiers in Immunology CrossRef - Imbalance of Th22/Treg cells causes microinflammation in uremic patients undergoing hemodialysis
Tingting Ren et al, 2019, Bioscience Reports CrossRef - Indoleamine 2,3‑dioxygenase suppresses humoral alloimmunity via pathways that different to those associated with its effects on T cells
Maria Sounidaki et al, 2019, Biomedical Reports CrossRef - An integrated cytokine and kynurenine network as the basis of neuroimmune communication
Trevor W. Stone et al, 2022, Frontiers in Neuroscience CrossRef - Increased kynurenine-to-tryptophan ratio in the serum of patients infected with SARS-CoV2: An observational cohort study.
Luana Lionetto et al, 2021, Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease CrossRef - Crystalline silica activates the T-cell and the B-cell antigen receptor complexes and induces T-cell and B-cell proliferation
Theodoros Eleftheriadis et al, 2019, Autoimmunity CrossRef - Urate crystals directly activate the T-cell receptor complex and induce T-cell proliferation
Theodoros Eleftheriadis et al, 2017, Biomedical Reports CrossRef - Tryptophan deficiency induced by indoleamine 2,3‐dioxygenase 1 results in glucose transporter 1‐dependent promotion of aerobic glycolysis in pancreatic cancer
Heng Liang et al, 2024, MedComm CrossRef - Multiple Roles of the Stress Sensor GCN2 in Immune Cells
Chenxu Zhao et al, 2023, International Journal of Molecular Sciences CrossRef - Dietary Tryptophan Plays a Role as an Anti-Inflammatory Agent in European Seabass (Dicentrarchus labrax) Juveniles during Chronic Inflammation
Rita Azeredo et al, 2024, Biology CrossRef