1. Pharmacological properties and derivatives of shikonin—A review in recent years
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  2. Shikonin inhibits cancer cell cycling by targeting Cdc25s
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  3. Shikonin derivatives for cancer prevention and therapy
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  4. JKST6, a novel multikinase modulator of the BCR-ABL1/STAT5 signaling pathway that potentiates direct BCR-ABL1 inhibition and overcomes imatinib resistance in chronic myelogenous leukemia
    Haidée Aranda-Tavío et al, 2021, Biomedicine & Pharmacotherapy CrossRef
  5. Shikonin Inhibits Cancer Through P21 Upregulation and Apoptosis Induction
    Fangfang Wang et al, 2020, Frontiers in Pharmacology CrossRef
  6. Synthesis, biological function and evaluation of Shikonin in cancer therapy
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  7. Shikonin Derivatives Inhibit Inflammation Processes and Modulate MAPK Signaling in Human Healthy and Osteoarthritis Chondrocytes
    Birgit Lohberger et al, 2022, International Journal of Molecular Sciences CrossRef
  8. Shikonin Derivatives from Onsoma visianii Decrease Expression of Phosphorylated STAT3 in Leukemia Cells and Exert Antitumor Activity
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  9. The anti-leukemia activity and mechanisms of shikonin: a mini review
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  10. Two novel 1,4‑naphthoquinone derivatives induce human gastric cancer cell apoptosis and cell cycle arrest by regulating reactive oxygen species‑mediated MAPK/Akt/STAT3 signaling pathways
    Hao Wang et al, 2019, Molecular Medicine Reports CrossRef
  11. Recent advances in shikonin for the treatment of immune-related diseases: Anti-inflammatory and immunomodulatory mechanisms
    Yimeng Guo et al, 2023, Biomedicine & Pharmacotherapy CrossRef
  12. Dexmedetomidine Alleviates Lipopolysaccharide-Induced Hippocampal Neuronal Apoptosis via Inhibiting the p38 MAPK/c-Myc/CLIC4 Signaling Pathway in Rats
    Yongping Chen et al, 2021, Molecular Neurobiology CrossRef
  13. Shikonin inhibits the proliferation of cervical cancer cells via FAK/AKT/GSK3β signalling
    Ziyan Xu et al, 2022, Oncology Letters CrossRef
  14. Shikonin derivatives cause apoptosis and cell cycle arrest in human chondrosarcoma cells via death receptors and MAPK regulation
    Birgit Lohberger et al, 2022, BMC Cancer CrossRef
  15. Shikonin Causes an Apoptotic Effect on Human Kidney Cancer Cells through Ras/MAPK and PI3K/AKT Pathways
    József Király et al, 2023, Molecules CrossRef
  16. MYC Oncogene: A Druggable Target for Treating Cancers with Natural Products
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  17. Shikonin Induced Program Cell Death through Generation of Reactive Oxygen Species in Renal Cancer Cells
    Ming-Feng Tsai et al, 2021, Antioxidants CrossRef
  18. In vitro mass production, chemical modification, and cytotoxicity of shikonin derivatives on breast cancer cells
    Melike Tepe et al, 2023, Industrial Crops and Products CrossRef
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    Hua Luo et al, 2019, Chinese Medicine CrossRef
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    Shengjun Ma et al, 2022, Recent Patents on Anti-Cancer Drug Discovery CrossRef