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2. MiR-30a regulates the proliferation, migration, and invasion of human osteosarcoma by targeting Runx2
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3. Downregulation of microRNA-497 is associated with upregulation of synuclein γ in patients with osteosarcoma
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4. Identification of candidate drugs for the treatment of metastatic osteosarcoma through a subpathway analysis method
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5. Doxorubicin activates the Notch signaling pathway in osteosarcoma
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6. Long non-coding RNA THOR promotes human osteosarcoma cell growth in vitro and in vivo
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7. Long non-coding RNA ASBEL promotes osteosarcoma cell proliferation, migration, and invasion by regulating microRNA-21
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8. Vincristine-loaded hydroxyapatite nanoparticles as a potential delivery system for bone cancer therapy
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9. Long noncoding RNA SNHG12 mediates doxorubicin resistance of osteosarcoma via miR-320a/MCL1 axis.
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10. Adenovirus-mediated small interfering RNA targeting ezrin induces apoptosis and inhibits metastasis of human osteosarcoma MG-63 cells
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11. DOX-Vit D, a Novel Doxorubicin Delivery Approach, Inhibits Human Osteosarcoma Cell Proliferation by Inducing Apoptosis While Inhibiting Akt and mTOR Signaling Pathways
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12. The possible role of insulin-like growth factor-1 in osteosarcoma
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13. Synergistic inhibitory effects of capsaicin combined with cisplatin on human osteosarcoma in culture and in xenografts
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14. Androgen receptor (AR)/miR-520f-3p/SOX9 signaling is involved in the altering hepatocellular carcinoma (HCC) cell sensitivity to the Sorafenib therapy under hypoxia via increasing cancer stem cells phenotype
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15. Functionalized Keratin as Nanotechnology-Based Drug Delivery System for the Pharmacological Treatment of Osteosarcoma
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16. Norcantharidin inhibits proliferation and promotes apoptosis via c-Met/Akt/mTOR pathway in human osteosarcoma cells
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17. Drug resistance‐related microRNAs in osteosarcoma: Translating basic evidence into therapeutic strategies
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18. Metallothionein: Potential therapeutic target for osteosarcoma
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19. ABCG1 and Pgp identify drug resistant, self-renewing osteosarcoma cells.
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20. Role of autophagy in osteosarcoma.
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21. miRNA signatures in childhood sarcomas and their clinical implications
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23. Ablation of MCL1 expression by virally induced microRNA-29 reverses chemoresistance in human osteosarcomas.
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24. Long noncoding RNAs in the progression, metastasis, and prognosis of osteosarcoma
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25. MicroRNA-26a inhibits osteosarcoma cell proliferation by targeting IGF-1
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26. Lack of efficacy of neoadjuvant chemotherapy in adult patients with maxillo-facial high-grade osteosarcomas: A French experience in two reference centers
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27. Anti-tumor efficacy of phellamurin in osteosarcoma cells: Involvement of the PI3K/AKT/mTOR pathway.
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28. Nomograms predicting overall survival and cancer-specific survival in osteosarcoma patients (STROBE)
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30. Mutant p53 gain of function induces HER2 over-expression in cancer cells
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31. MicroRNA-221 promotes cisplatin resistance in osteosarcoma cells by targeting PPP2R2A
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32. Osteomimetic matrix components alter cell migration and drug response in a 3D tumour-engineered osteosarcoma model
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33. In-Vitro and In-Vivo Establishment and Characterization of Bioluminescent Orthotopic Chemotherapy-Resistant Human Osteosarcoma Models in NSG Mice
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34. Pediatric Osteosarcoma of Extremities
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35. Checkpoint kinase inhibitor AZD7762 enhance cisplatin-induced apoptosis in osteosarcoma cells.
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36. Onco-epidemiology of domestic animals and targeted therapeutic attempts: perspectives on human oncology
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37. HMGB1 promotes cellular proliferation and invasion, suppresses cellular apoptosis in osteosarcoma
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38. Knockdown of autophagy-related protein 6, Beclin-1, decreases cell growth, invasion, and metastasis and has a positive effect on chemotherapy-induced cytotoxicity in osteosarcoma cells
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39. MiR-135b promotes proliferation and invasion of osteosarcoma cells via targeting FOXO1
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40. Excision repair cross-complementation group 1 protein expression predicts survival in patients with high-grade, non-metastatic osteosarcoma treated with neoadjuvant chemotherapy
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41. Research progress on the multidrug resistance mechanisms of osteosarcoma chemotherapy and reversal.
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42. MicroRNAs in osteosarcoma
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43. The NF-κB pathway is critically implicated in the oncogenic phenotype of human osteosarcoma cells.
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44. Knockdown of ST6Gal-I inhibits the growth and invasion of osteosarcoma MG-63 cells
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45. Advances in emerging drugs for osteosarcoma
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46. BMI1 Is Expressed in Canine Osteosarcoma and Contributes to Cell Growth and Chemotherapy Resistance
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47. Effect of PI3K-mediated autophagy in human osteosarcoma MG63 cells on sensitivity to chemotherapy with cisplatin
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48. Morphological and Immunohistochemical Characterization of Canine Osteosarcoma Spheroid Cell Cultures
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49. Prognostic Significance of Survivin Expression in Osteosarcoma Patients: A Meta-Analysis
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50. Dual mTORC1/2 inhibition by INK-128 results in antitumor activity in preclinical models of osteosarcoma
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51. The regulatory and predictive functions of miR-17 and miR-92 families on cisplatin resistance of non-small cell lung cancer
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52. Green tea polyphenol EGCG suppresses osteosarcoma cell growth through upregulating miR-1
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53. Fibroblast growth factor receptor 1 promotes MG63 cell proliferation and is associated with increased expression of cyclin-dependent kinase 1 in osteosarcoma
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54. Twist mediates an aggressive phenotype in human colorectal cancer cells
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55. Hydrogen bonded and stacked geometries of the temozolomide dimer
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56. Aloe-emodin-mediated photodynamic therapy induces autophagy and apoptosis in human osteosarcoma cell line MG-63 through the ROS/JNK signaling pathway
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57. Histone Deacetylase 4 Promotes Osteosarcoma Cell Proliferation and Invasion by Regulating Expression of Proliferating Cell Nuclear Antigen
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58. Elimination of Osteosarcoma by Necroptosis with Graphene Oxide-Associated Anti-HER2 Antibodies
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59. Fibulin-4 is a novel Wnt/β-Catenin pathway activator in human osteosarcoma
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60. Overexpression of pyruvate kinase M2 predicts a poor prognosis for patients with osteosarcoma.
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61. Anticancer effect of thalidomide in vitro on human osteosarcoma cells
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62. GFRA1 promotes cisplatin-induced chemoresistance in osteosarcoma by inducing autophagy
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63. Review of Osteosarcoma and Current Management.
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64. Cinobufagin induces apoptosis of osteosarcoma cells through inactivation of Notch signaling.
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65. Foscan and foslip based photodynamic therapy in osteosarcomain vitroand in intratibial mouse models
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66. Oncolytic adenoviruses as a therapeutic approach for osteosarcoma: A new hope
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67. Exosomal MiRNAs in Pediatric Cancers
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68. Disturbance of the let-7/LIN28 double-negative feedback loop is associated with radio- and chemo-resistance in non-small cell lung cancer
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69. Involvement of c-Fos in cell proliferation, migration, and invasion in osteosarcoma cells accompanied by altered expression of Wnt2 and Fzd9
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70. MicroRNA-302a suppresses cell proliferation, migration and invasion in osteosarcoma by targeting ADAM9
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71. miR-491-3p suppresses the growth and invasion of osteosarcoma cells by targeting TSPAN1.
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72. Potential therapeutic implications of miRNAs in osteosarcoma chemotherapy
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73. miR-342-5p inhibits osteosarcoma cell growth, migration, invasion, and sensitivity to Doxorubicin through targeting Wnt7b
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74. PAXX is a novel target to overcome resistance to doxorubicin and cisplatin in osteosarcoma
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75. Cancer Stem Cells and Osteosarcoma
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76. Synergistic Autophagy Effect of miR-212-3p in Zoledronic Acid-Treated In Vitro and Orthotopic In Vivo Models and in Patient-Derived Osteosarcoma Cells
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77. The Potential Selective Cytotoxicity of Poly (L- Lactic Acid)-Based Scaffolds Functionalized with Nanohydroxyapatite and Europium (III) Ions toward Osteosarcoma Cells
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78. Increased expression of ecotropic viral integration site 2A indicates a poor prognosis and promotes osteosarcoma evolution through activating MEK/ERK pathway
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79. PEG-sheddable reduction-sensitive polyurethane micelles for triggered intracellular drug delivery for osteosarcoma treatment
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80. Regulation of ATP‐binding cassette subfamily B member 1 by Snail contributes to chemoresistance in colorectal cancer
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81. piR‐39980 promotes cell proliferation, migration and invasion, and inhibits apoptosis via repression of SERPINB1 in human osteosarcoma
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82. Delineation of hypoxia-induced proteome shifts in osteosarcoma cells with different metastatic propensities
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83. Understanding and Modeling Metastasis Biology to Improve Therapeutic Strategies for Combating Osteosarcoma Progression
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84. Application of artificial intelligence in modeling of the doxorubicin release behavior of pH and temperature responsive poly(NIPAAm-co-AAc)-PEG IPN hydrogel
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85. miR-492 promotes chemoresistance to CDDP and metastasis by targeting inhibiting DNMT3B and induces stemness in gastric cancer
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86. MIR600HG suppresses metastasis and enhances oxaliplatin chemosensitivity by targeting ALDH1A3 in colorectal cancer.
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87. Leucine and branched-chain amino acid metabolism contribute to the growth of bone sarcomas by regulating AMPK and mTORC1 signaling
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88. The cyclin-dependent kinase inhibitor flavopiridol (alvocidib) inhibits metastasis of human osteosarcoma cells
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89. Long non-coding RNAs in osteosarcoma
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90. MiR-34a-5p promotes the multi-drug resistance of osteosarcoma by targeting the CD117 gene
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91. Cell apoptosis, autophagy and necroptosis in osteosarcoma treatment
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92. Cisplatin selects for stem-like cells in osteosarcoma by activating Notch signaling
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93. Selective Activation of ZAK β Expression by 3-Hydroxy-2-Phenylchromone Inhibits Human Osteosarcoma Cells and Triggers Apoptosis via JNK Activation
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94. ERK inhibition sensitizes CZ415-induced anti-osteosarcoma activity in vitro and in vivo
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95. Circulating biomarkers in osteosarcoma: new translational tools for diagnosis and treatment
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96. The anti-cancer activity of the mTORC1/2 dual inhibitor XL388 in preclinical osteosarcoma models
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97. miR-382 inhibits tumor growth and enhance chemosensitivity in osteosarcoma
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98. CircUBAP2 promotes SEMA6D expression to enhance the cisplatin resistance in osteosarcoma through sponging miR-506-3p by activating Wnt/β-catenin signaling pathway
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99. Untargeted LC–MS/MS analysis reveals metabolomics feature of osteosarcoma stem cell response to methotrexate
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100. Small Nucleolar RNAs Determine Resistance to Doxorubicin in Human Osteosarcoma
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101. TGM2 knockdown reverses cisplatin chemoresistance in osteosarcoma.
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102. MicroRNA-124 suppresses growth and aggressiveness of osteosarcoma and inhibits TGF-β-mediated AKT/GSK-3β/SNAIL-1 signaling
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103. Targeting autophagy is a promising therapeutic strategy to overcome chemoresistance and reduce metastasis in osteosarcoma
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104. Honokiol suppresses proliferation and induces apoptosis via regulation of the miR‑21/PTEN/PI3K/AKT signaling pathway in human osteosarcoma cells.
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105. Target therapy of TRIM-14 inhibits osteosarcoma aggressiveness through the nuclear factor-κB signaling pathway
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106. Plasma-stimulated medium kills TRAIL-resistant human malignant cells by promoting caspase-independent cell death via membrane potential and calcium dynamics modulation
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107. Identification of biomarkers associated with the recurrence of osteosarcoma using ceRNA regulatory network analysis
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108. MicroRNA-18a inhibits cell growth and induces apoptosis in osteosarcoma by targeting MED27
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109. Necrosis of osteosarcoma cells induces the production and release of high-mobility group box 1 protein.
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110. β‑elemene enhances anticancer bone neoplasms efficacy of paclitaxel through regulation of GPR124 in bone neoplasms cells
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111. Targeted MEK inhibition by cobimetinib enhances doxorubicin’s efficacy in osteosarcoma models
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112. Pseudogene MSTO2P enhances hypoxia-induced osteosarcoma malignancy by upregulating PD-L1
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113. LncRNA ADAMTS9-AS2 in osteosarcoma inhibits cell proliferation and enhances paclitaxel sensitivity by suppressing microRNA-130a-5p
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114. Systems Biology Approach Identifies Prognostic Signatures of Poor Overall Survival and Guides the Prioritization of Novel BET-CHK1 Combination Therapy for Osteosarcoma
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115. Flavonoid compound breviscapine suppresses human osteosarcoma Saos‐2 progression property and induces apoptosis by regulating mitochondria‐dependent pathway
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116. Acquisition of cancer stem cell properties in osteosarcoma cells by defined factors.
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117. LncRNA KRAL suppresses cell growth and increases sensitivity to doxorubicin in osteosarcoma cells by sponging microRNAs-141
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118. Pioglitazone modulates doxorubicin resistance in a in vivo model of drug resistant osteosarcoma xenograft
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119. A Correlation Between Intracellular Zinc Content and Osteosarcoma
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120. A Comparative Oncology Drug Discovery Pipeline to Identify and Validate New Treatments for Osteosarcoma
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121. Inhibition of copper chaperones sensitizes human and canine osteosarcoma cells to carboplatin chemotherapy
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122. Eldecalcitol induces apoptosis and autophagy in human osteosarcoma MG-63 cells by accumulating ROS to suppress the PI3K/Akt/mTOR signaling pathway
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123. Identification of plasma microRNA-22 as a marker for the diagnosis, prognosis, and chemosensitivity prediction of osteosarcoma
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124. Targeting Super-Enhancer–Associated Oncogenes in Osteosarcoma with THZ2, a Covalent CDK7 Inhibitor
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125. Recent Insights into Therapy Resistance in Osteosarcoma
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126. Non-Rodent Animal Models of Osteosarcoma: A Review
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127. Sensitivity of Osteosarcoma Cells to Concentration-Dependent Bioactivities of Lipid Peroxidation Product 4-Hydroxynonenal Depend on Their Level of Differentiation
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128. Overexpression of miR‐329‐3p sensitizes osteosarcoma cells to cisplatin through suppression of glucose metabolism by targeting LDHA
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129. Mechanisms of Resistance to Conventional Therapies for Osteosarcoma
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130. The LINC01410/miR-122-5p/NDRG3 axis is involved in the proliferation and migration of osteosarcoma cells.
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131. circPVT1 promotes osteosarcoma glycolysis and metastasis by sponging miR-423-5p to activate Wnt5a/Ror2 signaling.
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132. Transcription factor ELK1 accelerates aerobic glycolysis to enhance osteosarcoma chemoresistance through miR-134/PTBP1 signaling cascade
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133. Prothymosin α promotes colorectal carcinoma chemoresistance through inducing lipid droplet accumulation
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134. Circular RNA circPVT1 Contributes to Doxorubicin (DXR) Resistance of Osteosarcoma Cells by Regulating TRIAP1 via miR-137
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135. Down‐regulation of circITCH promotes osteosarcoma development and resistance to doxorubicin via the miR‐524/RASSF6 axis
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136. Exosomal miRNA-205 promotes breast cancer chemoresistance and tumorigenesis through E2F1
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137. Combination Therapy of Cisplatin and other Agents for Osteosarcoma: A Review
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138. Effect of the Notch1-mediated PI3K-Akt-mTOR pathway in human osteosarcoma
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140. Evaluation of the Chemotherapy Drug Response Using Organotypic Cultures of Osteosarcoma Tumours from Mice Models and Canine Patients
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141. Indocyanine Green for Leakage Control in Isolated Limb Perfusion
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142. Chondroblastic Osteosarcoma of the Mandible in a Patient on Risedronate: A Rare Case of Neoadjuvant Chemotherapy Failure
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143. Doxorubicin Inhibits Proliferation of Osteosarcoma Cells Through Upregulation of the Notch Signaling Pathway
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144. MicroRNA-20b Downregulates HIF-1α and Inhibits the Proliferation and Invasion of Osteosarcoma Cells
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145. The role of vascular endothelial growth factor as a prognostic and clinicopathological marker in osteosarcoma: a systematic review and meta-analysis
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146. Exosomal Long Non-Coding RNA ANCR Mediates Drug Resistance in Osteosarcoma
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147. Metastatic Progression of Osteosarcomas: A Review of Current Knowledge of Environmental versus Oncogenic Drivers
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148. Evaluation of the expression level of apoptosis and ferroptosis cell death pathways genes in patients with osteosarcoma
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149. Falcarindiol Stimulates Apoptotic and Autophagic Cell Death to Attenuate Cell Proliferation, Cell Division, and Metastasis through the PI3K/AKT/mTOR/p70S6K Pathway in Human Oral Squamous Cell Carcinomas
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150. Bifunctional scaffolds for tumor therapy and bone regeneration: Synergistic effect and interplay between therapeutic agents and scaffold materials
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151. Ginsenoside Rg5 Sensitizes Paclitaxel—Resistant Human Cervical-Adeno-Carcinoma Cells to Paclitaxel—And Enhances the Anticancer Effect of Paclitaxel
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152. IGF2BP1-regulated expression of ERRα is involved in metabolic reprogramming of chemotherapy resistant osteosarcoma cells
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153. Comparison of Selected Non-Coding RNAs and Gene Expression Profiles between Common Osteosarcoma Cell Lines
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154. Nano/micro-formulations of keratin in biocomposites, wound healing and drug delivery systems; recent advances in biomedical applications
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155. Induced resistance to ifosfamide in osteosarcoma cells suggests a more aggressive tumor profile
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156. CAF-derived midkine promotes EMT and cisplatin resistance by upregulating lncRNA ST7-AS1 in gastric cancer
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157. Noncoding RNA PVT1 in osteosarcoma: The roles of lncRNA PVT1 and circPVT1
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158. Effect of different solvents on nisin ZP potential as anticancer agent against MG-63 osteosarcoma cells
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159. LAMTOR5-AS1 regulates chemotherapy-induced oxidative stress by controlling the expression level and transcriptional activity of NRF2 in osteosarcoma cells
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