1. Emerging role of plumbagin: Cytotoxic potential and pharmaceutical relevance towards cancer therapy
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  2. Bioinformatic and experimental data decipher the pharmacological targets and mechanisms of plumbagin against hepatocellular carcinoma
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  3. Natural products modulate NLRP3 in ulcerative colitis
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  4. Plumbagin attenuates traumatic tracheal stenosis in rats and inhibits lung fibroblast proliferation and differentiation via TGF-β1/Smad and Akt/mTOR pathways
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  5. Discovery and cellular stress pathway analysis of 1,4-naphthoquinone derivatives with novel, highly potent broad-spectrum anticancer activity
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  8. Anti-cancer effects of Polyphyllin I: An update in 5 years
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  9. Plumbagin inhibits the proliferation of nasopharyngeal carcinoma 6-10B cells by upregulation of reactive oxygen species
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  10. Plumbagin induces ROS-mediated apoptosis and cell cycle arrest and inhibits EMT in human cervical carcinoma cells
    Ankita Jaiswal et al, 2018, RSC Advances CrossRef
  11. Plumbagin Prevents Secretory Diarrhea by Inhibiting CaCC and CFTR Channel Activities
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  12. Resibufogenin inhibits the malignant characteristics of multiple myeloma cells by blocking the PI3K/Akt signaling pathway
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  13. Discovery of 4,6-O-Thenylidene-β-d-glucopyranoside-(2″-acetamido, 3″-acetyl-di-S-5-fluorobenzothizole/5-fluorobenzoxazole)-4′-demethylepipodophyllotoxin as Potential Less Toxic Antitumor Candidate Drugs by Reducing DNA Damage and Less Inhibition of PI3K
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  14. Occurrence and Diversity of Major Naphthoquinones in Higher Plants: Their Distribution and Conservation Strategies
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  15. Cytokine-Mediated Dysregulation of Signaling Pathways in the Pathogenesis of Multiple Myeloma
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  16. Developing a molecular roadmap to Narasimha Rasayana: A system Polypharmacology approach
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  17. Exogenous H2S exerts biphasic effects on porcine mammary epithelial cells proliferation through PI3K/Akt‐mTOR signaling pathway
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  18. Safflower polysaccharide induces cervical cancer cell apoptosis via inhibition of the PI3K/Akt pathway
    J. Yang et al, 2018, South African Journal of Botany CrossRef
  19. Plumbagin Suppresses Breast Cancer Progression by Downregulating HIF-1α Expression via a PI3K/Akt/mTOR Independent Pathway under Hypoxic Condition
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  20. Plumbagin inhibits proliferation and promotes apoptosis of ovarian granulosa cells in polycystic ovary syndrome by inactivating PI3K/Akt/mTOR pathway
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  21. Phytochemicals and PI3K Inhibitors in Cancer—An Insight
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