- TH588, an MTH1 inhibitor, enhances phenethyl isothiocyanate‑induced growth inhibition in pancreatic cancer cells
Fumiyoshi Ikejiri et al, 2017, Oncology Letters CrossRef - hMTH1 is required for maintaining migration and invasion potential of human thyroid cancer cells
Katarzyna D. Arczewska et al, 2018, DNA Repair CrossRef - Inhibitor development of MTH1 via high-throughput screening with fragment based library and MTH1 substrate binding cavity
Cheng Peng et al, 2021, Bioorganic Chemistry CrossRef - MTH1 suppression enhances the stemness of MCF7 through upregulation of STAT3
Jin Li et al, 2022, Free Radical Biology and Medicine CrossRef - MTH1 is involved in the toxic and carcinogenic long-term effects induced by zinc oxide and cobalt nanoparticles
Irene Barguilla et al, 2020, Archives of Toxicology CrossRef - The MTH1 inhibitor TH588 is a microtubule-modulating agent that eliminates cancer cells by activating the mitotic surveillance pathway
Nadia Gul et al, 2019, Scientific Reports CrossRef - Radiolabeled 6-(2, 3-Dichlorophenyl)-N4-methylpyrimidine-2, 4-diamine (TH287): A Potential Radiotracer for Measuring and Imaging MTH1
Huaping Chen et al, 2020, International Journal of Molecular Sciences CrossRef - Simultaneous characterization of nine isolated flavonoids in Iranian Dracocephalum species and in silico study of their inhibitory properties against MTH1 enzyme
Shahrbanou Ashrafian et al, 2022, South African Journal of Botany CrossRef - Exploring MTH1 inhibitory potential of Thymoquinone and Baicalin for therapeutic targeting of breast cancer
Aaliya Taiyab et al, 2024, Biomedicine & Pharmacotherapy CrossRef - Specific 8-oxo-dGTPase activity of MTH1 (NUDT1) protein as a quantitative marker and prognostic factor in human colorectal cancer
Karol Bialkowski et al, 2021, Free Radical Biology and Medicine CrossRef - lncRNA AFAP1-AS1 promotes triple negative breast cancer cell proliferation and invasion via targeting miR-145 to regulate MTH1 expression
Xiaohui Zhang et al, 2020, Scientific Reports CrossRef - Oxidative Damage in Sporadic Colorectal Cancer: Molecular Mapping of Base Excision Repair Glycosylases in Colorectal Cancer Patients
Pavel Vodicka et al, 2020, International Journal of Molecular Sciences CrossRef - RAD51 Expression as a Biomarker to Predict Efficacy of Preoperative Therapy and Survival for Esophageal Squamous Cell Carcinoma
Hiroshi Saeki et al, 2022, Annals of Surgery CrossRef - MTH1 Inhibitors for the Treatment of Psoriasis
Cecilia Bivik Eding et al, 2021, Journal of Investigative Dermatology CrossRef - Targeting MutT Homolog 1 (MTH1) for Breast Cancer Suppression by Using a Novel MTH1 Inhibitor MA−24 with Tumor-Selective Toxicity
Nannan Kang et al, 2024, Pharmaceuticals CrossRef - Potent and specific MTH1 inhibitors targeting gastric cancer
Wenjuan Zhou et al, 2019, Cell Death & Disease CrossRef - Role of the NUDT Enzymes in Breast Cancer
Roni H. G. Wright et al, 2021, International Journal of Molecular Sciences CrossRef