1. Multicellular Human Gastric Cancer Spheroids Mimic the Glycosylation Phenotype of Gastric Carcinomas
    Meritxell Balmaña et al, 2018, Molecules CrossRef
  2. Cellular Spheroids of Mesenchymal Stem Cells and Their Perspectives in Future Healthcare
    Hao-Wei Han et al, 2019, Applied Sciences CrossRef
  3. Influence of the static magnetic field on cell response in a miniaturized optically accessible bioreactor for 3D cell culture
    Luca Izzo et al, 2019, Biomed Microdevices CrossRef
  4. Integrating Microfabrication into Biological Investigations: the Benefits of Interdisciplinarity
    Gianluca Grenci et al, 2019, Micromachines CrossRef
  5. A High Throughput Apoptosis Assay using 3D Cultured Cells
    Sang-Yun Lee et al, 2019, Molecules CrossRef
  6. Single Cell Mass Cytometry of Non-Small Cell Lung Cancer Cells Reveals Complexity of In vivo And Three-Dimensional Models over the Petri-dish
    null Alföldi et al, 2019, Cells CrossRef
  7. Patient-Derived Glioma Models: From Patients to Dish to Animals
    Cintia Carla da Hora et al, 2019, Cells CrossRef
  8. A Cancer Spheroid Array Chip for Selecting Effective Drug
    Jae Won Choi et al, 2019, Micromachines CrossRef
  9. Development and Evaluation of Paclitaxel-Loaded Aerosol Nanocomposite Microparticles and Their Efficacy Against Air-Grown Lung Cancer Tumor Spheroids
    Elisa A. Torrico Guzmán et al, 2019, ACS Biomater. Sci. Eng. CrossRef
  10. Three-dimensional cell culture systems as an in vitro platform for cancer and stem cell modeling
    Nipha Chaicharoenaudomrung et al, 2019, WJSC CrossRef
  11. A Hepatic Scaffold from Decellularized Liver Tissue: Food for Thought
    Stefania Croce et al, 2019, Biomolecules CrossRef
  12. Human Adipose-Derived Hydrogel Characterization Based on In Vitro ASC Biocompatibility and Differentiation
    Omair A. Mohiuddin et al, 2019, Stem Cells International CrossRef
  13. Is It Time to Start Transitioning From 2D to 3D Cell Culture?
    Caleb Jensen et al, 2020, Front. Mol. Biosci. CrossRef
  14. Modeling the Efficacy of Oncolytic Adenoviruses In Vitro and In Vivo: Current and Future Perspectives
    Mary K. McKenna et al, 2020, Cancers CrossRef
  15. The preparation of cell-containing microbubble scaffolds to mimic alveoli structure as a 3D drug-screening system for lung cancer
    Yu-Jun Sun et al, 2020, Biofabrication CrossRef
  16. Laser-assisted 3D bioprinting of exocrine pancreas spheroid models for cancer initiation study
    Davit Hakobyan et al, 2020, Biofabrication CrossRef
  17. Mimicking tumor hypoxia and tumor-immune interactions employing three-dimensional in vitro models
    Somshuvra Bhattacharya et al, 2020, J Exp Clin Cancer Res CrossRef
  18. Microphysiological Systems: Design, Fabrication, and Applications
    Kai Wang et al, 2020, ACS Biomater. Sci. Eng. CrossRef
  19. Knockout of MMP3 Weakens Solid Tumor Organoids and Cancer Extracellular Vesicles
    Eman Taha et al, 2020, Cancers CrossRef
  20. Biomaterial 3D collagen I gel culture model: A novel approach to investigate tumorigenesis and dormancy of bladder cancer cells induced by tumor microenvironment
    Yaqi Qiu et al, 2020, Biomaterials CrossRef
  21. Characterization of Hen’s Egg White To Use It as a Novel Platform To Culture Three-Dimensional Multicellular Tumor Spheroids
    Perumalsamy Balaji et al, 2020, ACS Omega CrossRef
  22. Organoids in Translational Oncology
    Marco Tatullo et al, 2020, JCM CrossRef
  23. Spheroids as a Type of Three-Dimensional Cell Cultures—Examples of Methods of Preparation and the Most Important Application
    Kamila Białkowska et al, 2020, IJMS CrossRef
  24. Three-Dimensional Cell Cultures as an In Vitro Tool for Prostate Cancer Modeling and Drug Discovery
    Fabrizio Fontana et al, 2020, IJMS CrossRef
  25. Current updates and future perspectives on the management of renal cell carcinoma.
    Deepika Singh, 2021, Life Sci CrossRef
  26. Digital Image Analysis Applied to Tumor Cell Proliferation, Aggressiveness, and Migration-Related Protein Synthesis in Neuroblastoma 3D Models
    Ezequiel Monferrer et al, 2020, IJMS CrossRef
  27. Potential impact of tissue molecular heterogeneity on ambient mass spectrometry profiles: a note of caution in choosing the right disease model
    Lauren Katz et al, 2020, Anal Bioanal Chem CrossRef
  28. Overview of the Anticancer Potential of the “King of Spices” Piper nigrum and Its Main Constituent Piperine
    Eleonora Turrini et al, 2020, Toxins CrossRef
  29. null
    Natasha Karassina et al, 2021 CrossRef
  30. Cancer Stem Cell Microenvironment Models with Biomaterial Scaffolds In Vitro
    Ghmkin Hassan et al, 2020, Processes CrossRef
  31. 3D Culture Systems for Exploring Cancer Immunology
    Allison A. Fitzgerald et al, 2020, Cancers CrossRef
  32. m6A-RNA Demethylase FTO Inhibitors Impair Self-Renewal in Glioblastoma Stem Cells.
    Sarah Huff et al, 2021, ACS Chem Biol CrossRef
  33. Polysaccharide hydrogel based 3D printed tumor models for chemotherapeutic drug screening
    Aragaw Gebeyehu et al, 2021, Sci Rep CrossRef
  34. Studies on host-foodborne bacteria in intestinal three-dimensional cell culture model indicate possible mechanisms of interaction
    Marita Gimenez Pereira et al, 2021, World J Microbiol Biotechnol CrossRef
  35. Mimicking Tumor Hypoxia in Non-Small Cell Lung Cancer Employing Three-Dimensional In Vitro Models
    Iwona Ziółkowska-Suchanek, 2021, Cells CrossRef
  36. 3D Cell Cultures as Prospective Models to Study Extracellular Vesicles in Cancer
    Guillermo Bordanaba-Florit et al, 2021, Cancers CrossRef
  37. null
    Shalini Dasgupta et al, 2021 CrossRef
  38. Digital Twins for Tissue Culture Techniques—Concepts, Expectations, and State of the Art
    Johannes Möller et al, 2021, Processes CrossRef
  39. Targeting Several Biologically Reported Targets of Glioblastoma Multiforme by Assaying 2D and 3D Cultured Cells
    Yudibeth Sixto-López et al, 2021, Cell Mol Neurobiol CrossRef
  40. Alginate–gelatin–Matrigel hydrogels enable the development and multigenerational passaging of patient-derived 3D bioprinted cancer spheroid models
    Salvador Flores-Torres et al, 2021, Biofabrication CrossRef
  41. Simplified ARCHITECT microfluidic chip through a dual-flip strategy enables stable and versatile tumoroid formation combined with label-free quantitative proteomic analysis
    Danni Feng et al, 2021, Biofabrication CrossRef
  42. Three Dimensional Cell Culturing for Modeling Adrenal and Pituitary Tumors
    Lilla Krokker et al, 2021, Pathol. Oncol. Res. CrossRef
  43. Coumarin-Chalcone Hybrids as Inhibitors of MAO-B: Biological Activity and In Silico Studies
    Guillermo Moya-Alvarado et al, 2021, Molecules CrossRef
  44. Extracellular Vesicle Mediated Tumor-Stromal Crosstalk Within an Engineered Lung Cancer Model
    Kayla F. Goliwas et al, 2021, Front. Oncol. CrossRef
  45. The Molecular Basis of Different Approaches for the Study of Cancer Stem Cells and the Advantages and Disadvantages of a Three-Dimensional Culture
    Danila Cianciosi et al, 2021, Molecules CrossRef
  46. Cell-cell and cell-substratum contacts in the regulation of MAPK and Akt signalling: Importance in therapy, biopharmacy and bioproduction
    Aurimas Stulpina et al, 2021, Cellular Signalling CrossRef
  47. Acoustic Droplet-Assisted Superhydrophilic–Superhydrophobic Microarray Platform for High-Throughput Screening of Patient-Derived Tumor Spheroids
    Yu Xia et al, 2021, ACS Appl. Mater. Interfaces CrossRef
  48. Quantitative and Qualitative Image Analysis of In Vitro Co-Culture 3D Tumor Spheroid Model by Employing Image-Processing Techniques
    Mukta Sharma et al, 2021, Applied Sciences CrossRef
  49. In Vitro 3D Cultures to Model the Tumor Microenvironment
    Fabrizio Fontana et al, 2021, Cancers CrossRef
  50. Engineering Breast Cancer On-chip—Moving Toward Subtype Specific Models
    Carmen Moccia et al, 2021, Front. Bioeng. Biotechnol. CrossRef
  51. Enhanced radiotherapy efficacy of breast cancer multi cellular tumor spheroids through in-situ fabricated chitosan-zinc oxide bio-nanocomposites as radio-sensitizing agents
    Zahra Arab-Bafrani et al, 2021, International Journal of Pharmaceutics CrossRef
  52. Airway and Alveoli Organoids as Valuable Research Tools in COVID-19
    Miriane de Oliveira et al, 2021, ACS Biomater. Sci. Eng. CrossRef
  53. Development and Validation of a Long-Term 3D Glioblastoma Cell Culture in Alginate Microfibers as a Novel Bio-Mimicking Model System for Preclinical Drug Testing
    Miodrag Dragoj et al, 2021, Brain Sciences CrossRef
  54. Central nervous system tumors and three-dimensional cell biology: Current and future perspectives in modeling
    Zaki Abou-Mrad et al, 2021, WJSC CrossRef
  55. Label-Free Magnetic-Field-Assisted Assembly of Layer-on-Layer Cellular Structures
    Tamaghna Gupta et al, 2020, ACS Biomater. Sci. Eng. CrossRef
  56. Collagen-Immobilized Extracellular FRET Reporter for Visualizing Protease Activity Secreted by Living Cells
    Hawon Lee et al, 2020, ACS Sens. CrossRef
  57. Leveraging advances in immunopathology and artificial intelligence to analyze in vitro tumor models in composition and space
    Matthew Leong Tze Ker et al, 2021, Advanced Drug Delivery Reviews CrossRef
  58. Interplay between Cellular and Non-Cellular Components of the Tumour Microenvironment in Hepatocellular Carcinoma
    Tamás Sükei et al, 2021, Cancers CrossRef
  59. Recent Advances in Multicellular Tumor Spheroid Generation for Drug Screening
    Kwang-Ho Lee et al, 2021, Biosensors CrossRef
  60. 3D Cell Culture Systems: Tumor Application, Advantages, and Disadvantages
    Ola Habanjar et al, 2021, IJMS CrossRef
  61. Synthetic Optimization and MAPK Pathway Activation Anticancer Mechanism of Polyisoprenylated Cysteinyl Amide Inhibitors
    Nada Tawfeeq et al, 2021, Cancers CrossRef
  62. Cannabidiol Induces Cell Death in Human Lung Cancer Cells and Cancer Stem Cells
    Hussein Hamad et al, 2021, Pharmaceuticals CrossRef
  63. null
    Heizel Rosado-Galindo et al, 2021 CrossRef
  64. The Effective Combination between 3D Cancer Models and Stimuli-Responsive Nanoscale Drug Delivery Systems
    Federica Foglietta et al, 2021, Cells CrossRef
  65. Three-Dimensional Cell Culture Models of Hepatocellular Carcinoma — a Review
    Irmak Ayvaz et al, 2021, J Gastrointest Canc CrossRef
  66. null
    S.A. Pullano et al, 2021 CrossRef
  67. Three-dimensional cell culture (3DCC) improves secretion of signaling molecules of mesenchymal stem cells (MSCs)
    Moyassar Basil Hadi Al-Shaibani, 2022, Biotechnol Lett CrossRef
  68. High-throughput screening for drug discovery targeting the cancer cell-microenvironment interactions in hematological cancers
    Anil K Giri et al, 2022, Expert Opinion on Drug Discovery CrossRef
  69. Substrate Stiffness Determines the Establishment of Apical-Basal Polarization in Renal Epithelial Cells but Not in Tubuloid-Derived Cells
    Maria J. Hagelaars et al, 2022, Front. Bioeng. Biotechnol. CrossRef
  70. Polymeric Hydrogels for In Vitro 3D Ovarian Cancer Modeling
    Simona Braccini et al, 2022, IJMS CrossRef
  71. Anti-Cancer Activity of Buthus occitanus Venom on Hepatocellular Carcinoma in 3D Cell Culture
    Ayoub Lafnoune et al, 2022, Molecules CrossRef
  72. Snake Venom and 3D Microenvironment Cell Culture: From Production to Drug Development
    Ellen Emi Kato et al, 2022, Future Pharmacology CrossRef
  73. Large-Scale Production of Size-Adjusted β-Cell Spheroids in a Fully Controlled Stirred-Tank Reactor
    Florian Petry et al, 2022, Processes CrossRef
  74. In Vitro Human Cancer Models for Biomedical Applications
    Jane Ru Choi et al, 2022, Cancers CrossRef
  75. Implications of Three-Dimensional Cell Culture in Cancer Therapeutic Research
    Kolluri Poornima et al, 2022, Front. Oncol. CrossRef
  76. Optimization of Biomimetic, Leukocyte-Mimicking Nanovesicles for Drug Delivery Against Colorectal Cancer Using a Design of Experiment Approach
    Riccardo Rampado et al, 2022, Front. Bioeng. Biotechnol. CrossRef
  77. Gossypol Induces Apoptosis of Human Pancreatic Cancer Cells via CHOP/Endoplasmic Reticulum Stress Signaling Pathway
    Soon Lee et al, 2022, J. Microbiol. Biotechnol. CrossRef
  78. Tissue Engineering and Photodynamic Therapy: A New Frontier of Science for Clinical Application -An Up-To-Date Review
    Mariza Aires-Fernandes et al, 2022, Front. Bioeng. Biotechnol. CrossRef
  79. Pineal Gland from the Cell Culture to Animal Models: A Review
    Alekhya Peruri et al, 2022, Life CrossRef
  80. Progressing Towards a Human-Centric Approach in Cancer Research
    Aditya Parekh et al, 2022, Front. Oncol. CrossRef
  81. An Optical and Chemiluminescence Assay for Assessing the Cytotoxicity of Balamuthia mandrillaris against Human Neurospheroids
    Worakamol Pengsart et al, 2022, Bioengineering CrossRef
  82. 3D Disease Modelling of Hard and Soft Cancer Using PHA-Based Scaffolds
    Akanksha Tomar et al, 2022, Cancers CrossRef
  83. Three-Dimensional In Vitro Cell Culture Models for Efficient Drug Discovery: Progress So Far and Future Prospects
    Shaimaa M. Badr-Eldin et al, 2022, Pharmaceuticals CrossRef
  84. Modelling acute myeloid leukemia (AML): What’s new? A transition from the classical to the modern
    Annachiara Dozzo et al, 2022, Drug Deliv. and Transl. Res. CrossRef
  85. A database of crop pest cell lines
    Surjeet Kumar Arya et al, 2022, In Vitro Cell.Dev.Biol.-Animal CrossRef
  86. Imitating Hypoxia and Tumor Microenvironment with Immune Evasion by Employing Three Dimensional In vitro Cellular Models: Impressive Tool in Drug Discovery
    Suman Kumar Ray et al, 2022, PRA CrossRef
  87. Understanding the mechano and chemo response of retinoblastoma tumor cells
    Gopal Divya et al, 2022, OpenNano CrossRef
  88. Optimization of 3D-aggregated spheroid model (3D-ASM) for selecting high efficacy drugs
    Sang-Yun Lee et al, 2022, Sci Rep CrossRef
  89. In situ 3D spatiotemporal measurement of soluble biomarkers in spheroid culture
    Alexander J. McGhee et al, 2022, In vitro models CrossRef
  90. Investigations of an organic–inorganic nanotheranostic hybrid for pancreatic cancer therapy using cancer-in-a-dish and in vivo models
    Karolyn Infanta David et al, 2023, Biomed. Mater. CrossRef
  91. The anticancer effects of Metformin in the male germ tumor SEM-1 cell line are mediated by HMGA1
    Alessandro Salatino et al, 2022, Front. Endocrinol. CrossRef
  92. Amplified Fenton-Based Oxidative Stress Utilizing Ultraviolet Upconversion Luminescence-Fueled Nanoreactors for Apoptosis-Strengthened Ferroptosis Anticancer Therapy
    Nguyen Thi Nguyen et al, 2022, ACS Nano CrossRef
  93. Microfluidically-generated Encapsulated Spheroids (μ-GELS): An All-Aqueous Droplet Microfluidics Platform for Multicellular Spheroids Generation
    Jennifer Kieda et al, 2023, ACS Biomater. Sci. Eng. CrossRef
  94. Distinct cholangiocarcinoma cell migration in 2D monolayer and 3D spheroid culture based on galectin-3 expression and localization
    Siriwat Sukphokkit et al, 2023, Front. Oncol. CrossRef
  95. Spheroid Engineering in Microfluidic Devices
    Atakan Tevlek et al, 2023, ACS Omega CrossRef
  96. Novel banana lectin CAR-T cells to target pancreatic tumors and tumor-associated stroma
    Mary K McKenna et al, 2023, J Immunother Cancer CrossRef
  97. Inclusion of cancer-associated fibroblasts in drug screening assays to evaluate pancreatic cancer resistance to therapeutic drugs.
    Sarah Brumskill et al, 2021, J Physiol Biochem CrossRef
  98. Insight into oral amphiphilic cyclodextrin nanoparticles for colorectal cancer: comprehensive mathematical model of drug release kinetic studies and antitumoral efficacy in 3D spheroid colon tumors
    Sedat Ünal et al, 2023, Beilstein J. Org. Chem. CrossRef
  99. O2-sensitive microcavity arrays: A new platform for oxygen measurements in 3D cell cultures
    Christoph Grün et al, 2023, Front. Bioeng. Biotechnol. CrossRef
  100. Primary colonospheres maintain stem cell-like key features after cryopreservation.
    Leila Eini et al, 2020, J Cell Physiol CrossRef
  101. null
    Siti M. G. Maya et al, 2023 CrossRef
  102. null
    Renata Lima et al, 2023 CrossRef
  103. null
    Malay Chaklader, 2023 CrossRef
  104. Squarate Cross-Linked Gelatin Hydrogels as Three-Dimensional Scaffolds for Biomedical Applications
    Simone Stucchi et al, 2021, Langmuir CrossRef
  105. The assessment of the potential hepatotoxicity of new drugs by in vitro metabolomics
    Guillermo Quintás et al, 2023, Front. Pharmacol. CrossRef
  106. SCALING OF VERO CELL CULTURE FOR THE PRODUCTION OF BIOLOGICAL PRODUCTS
    B. A. Seidakhmetova et al, 2022, jour CrossRef
  107. Murine models to study human NK cells in human solid tumors
    Monica Parodi et al, 2023, Front. Immunol. CrossRef
  108. Progress and promise of alternative animal and non-animal methods in biomedical research
    Irlan Almeida Freires et al, 2023, Arch Toxicol CrossRef
  109. 3D Bioprintable Hydrogel with Tunable Stiffness for Exploring Cells Encapsulated in Matrices of Differing Stiffnesses
    Eric Y. Du et al, 2023, ACS Appl. Bio Mater. CrossRef
  110. Measuring Drug Response with Single-Cell Growth Rate Quantification
    Fiona Xi Xu et al, 2023, Anal. Chem. CrossRef
  111. null
    Julien Claudel et al, 2023 CrossRef
  112. Development of a cancer metastasis-on-chip assay for high throughput drug screening
    Lutfiye Yildiz Ozer et al, 2024, Front. Oncol. CrossRef
  113. Construction of Scaffold-Free 3D Engineered Adipose
    博涛 高, 2024, ACM CrossRef
  114. Three-Dimensional Bioprinting of Organoids: Past, Present, and Prospective
    Mariana Cabral et al, 2024, Tissue Engineering Part A CrossRef
  115. Morphological, cytotoxic and apoptotic effects of different concentrations of nisin ZP on MG63 cells in a 3-dimensional culture system
    Alyaa R. Alkhateeb et al, 2024, APJMBB CrossRef
  116. Cellular and molecular antiproliferative effects in 2D monolayer and 3D-cultivated HT-29 cells treated with zerumbone
    Nayane de Oliveira Silva et al, 2024, Naunyn-Schmiedeberg's Arch Pharmacol CrossRef
  117. The role of decellularized cell derived extracellular matrix in the establishment and culture of in vitro breast cancer tumor model
    Atakan Tevlek, 2024, Biomed. Mater. CrossRef
  118. Anticancer Potential of the Principal Constituent of Piper nigrum, Piperine: A Comprehensive Review
    Vidhya Rekha Umapathy et al, 2024 CrossRef
  119. Recent Innovations in Strategies for Breast Cancer Therapy by Electrospun Scaffolds: A Review
    Sho’leh Ghaedamini et al, 2023, J Polym Environ CrossRef
  120. null
    Marna E. Sakalem et al, 2024 CrossRef
  121. Liquid overlay and collagen-based 3D models for in vitro investigation of multiple myeloma
    Jovana Ilic et al, 2024, Tissue Engineering Part C: Methods CrossRef