1. Discovery of Clinical Candidate (1R,4r)-4-((R)-2-((S)-6-Fluoro-5H-imidazo[5,1-a]isoindol-5-yl)-1-hydroxyethyl)cyclohexan-1-ol (Navoximod), a Potent and Selective Inhibitor of Indoleamine 2,3-Dioxygenase 1
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  2. Epithelial Ovarian Cancer and the Immune System: Biology, Interactions, Challenges and Potential Advances for Immunotherapy
    Anne M. Macpherson et al, 2020, Journal of Clinical Medicine CrossRef
  3. IDO1 Expression in Ovarian Cancer Induces PD-1 in T Cells via Aryl Hydrocarbon Receptor Activation
    Adaobi Amobi-McCloud et al, 2021, Frontiers in Immunology CrossRef
  4. Inflammation-Induced Tryptophan Breakdown is Related With Anemia, Fatigue, and Depression in Cancer
    Lukas Lanser et al, 2020, Frontiers in Immunology CrossRef
  5. Discovery and Characterisation of Dual Inhibitors of Tryptophan 2,3-Dioxygenase (TDO2) and Indoleamine 2,3-Dioxygenase 1 (IDO1) Using Virtual Screening
    Suat Sari et al, 2019, Molecules CrossRef
  6. The Tumor Microenvironment of Epithelial Ovarian Cancer and Its Influence on Response to Immunotherapy
    Galaxia Rodriguez et al, 2018, Cancers CrossRef
  7. Changes in the Tumor Immune Microenvironment during Disease Progression in Patients with Ovarian Cancer
    Marie Christine Wulff Westergaard et al, 2020, Cancers CrossRef
  8. Targeting Indoleamine 2,3-Dioxygenase in Cancer Models Using the Novel Small Molecule Inhibitor NTRC 3883-0
    Yvonne Grobben et al, 2021, Frontiers in Immunology CrossRef
  9. Clonality and antigen-specific responses shape the prognostic effects of tumor-infiltrating T cells in ovarian cancer
    Takemasa Tsuji et al, 2020, Oncotarget CrossRef
  10. Forkhead box P3 and indoleamine 2,3-dioxygenase co-expression in Pakistani triple negative breast cancer patients
    Kashif Asghar et al, 2020, World Journal of Clinical Oncology CrossRef
  11. IDO1 Modulates the Sensitivity of Epithelial Ovarian Cancer Cells to Cisplatin through ROS/p53-Dependent Apoptosis
    Houmei Wang et al, 2022, International Journal of Molecular Sciences CrossRef
  12. What May Constrain the Success of Indoleamine 2,3-Dioxygenase 1 Inhibitors in Cancer Immunotherapy?
    Theodoros Eleftheriadis, 2018, Frontiers in Immunology CrossRef