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  2. Ginsenoside Rh1 Improves the Effect of Dexamethasone on Autoantibodies Production and Lymphoproliferation in MRL/lpr Mice
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  3. New selenosteroids as antiproliferative agents
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  8. Estrogen receptor modulators genistein, daidzein and ERB-041 inhibit cell migration, invasion, proliferation and sphere formation via modulation of FAK and PI3K/AKT signaling in ovarian cancer
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  9. Diosgenin induces genotoxic and mutagenic effects on HepG2 cells
    Marina Sampaio Cruz et al, 2018, Food and Chemical Toxicology CrossRef
  10. Diosgenin inhibited the expression of TAZ in hepatocellular carcinoma
    Zhize Chen et al, 2018, Biochemical and Biophysical Research Communications CrossRef
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  12. Diosgenin exerts its tumor suppressive function via inhibition of Cdc20 in osteosarcoma cells.
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  14. 6-(4′-Aryl-1′,2′,3′-triazolyl)-spirostan-3,5-diols and 6-(4′-Aryl-1′,2′,3′-triazolyl)-7-hydroxyspirosta-1,4-dien-3-ones: Synthesis and analysis of their cytotoxicity
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    Laura L. Romero-Hernández et al, 2015, European Journal of Medicinal Chemistry CrossRef
  16. Diosgenin Mitigates Streptozotocin Diabetes-induced Vascular Dysfunction of the Rat Aorta
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  17. Synthesis and potent cytotoxic activity of a novel diosgenin derivative and its phytosomes against lung cancer cells
    Liang Xu et al, 2019, Beilstein J. Nanotechnol. CrossRef
  18. Diosgenyl Saponin Inducing Endoplasmic Reticulum Stress and Mitochondria-Mediated Apoptotic Pathways in Liver Cancer Cells
    Xin Meng et al, 2019, J. Agric. Food Chem. CrossRef
  19. Exploring the impact of a naturally occurring sapogenin diosgenin on underlying mechanisms of Ca 2+ movement and cytotoxicity in human prostate cancer cells
    Gwo‐Ching Sun et al, 2019, Environmental Toxicology CrossRef
  20. miR-363-3p inhibits tumor growth by targeting PCNA in lung adenocarcinoma
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    Jing Zhang et al, 2020, Advanced Drug Delivery Reviews CrossRef
  22. Recombinant PEP‑1‑SOD1 improves functional recovery after neural stem cell transplantation in rats with traumatic brain injury
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  23. The Role of Necroptosis in ROS-Mediated Cancer Therapies and Its Promising Applications
    Sheng-Kai Hsu et al, 2020, Cancers CrossRef
  24. Diosgenin, a steroidal saponin, and its analogues: Effective therapies against different chronic diseases
    Dey Parama et al, 2020, Life Sciences CrossRef
  25. Anti-proliferation and anti-migration effects of an aqueous extract of Cinnamomi ramulus on MH7A rheumatoid arthritis-derived fibroblast-like synoviocytes through induction of apoptosis, cell arrest and suppression of matrix metalloproteinase
    Jia Liu et al, 2020, Pharmaceutical Biology CrossRef
  26. Deciphering Antitumor Mechanism of Pien Tze Huang in Mice of Hepatocellular Carcinoma Based on Proteomics
    Dancai Fan et al, 2020, Journal of Immunology Research CrossRef
  27. Secondary Metabolites, Antioxidant, and Antiproliferative Activities of Dioscorea bulbifera Leaf Collected from Endau Rompin, Johor, Malaysia
    Muhammad Murtala Mainasara et al, 2021, Evidence-Based Complementary and Alternative Medicine CrossRef
  28. Evaluation of antioxidant, anti-inflammatory and anticancer activities of Diosgenin enriched Paris polyphylla rhizome extract of Indian Himalayan landraces
    Debmalya Das Gupta et al, 2021, Journal of Ethnopharmacology CrossRef
  29. Cytotoxic activity of standardized extracts, a fraction, and individual secondary metabolites from fenugreek seeds against SKOV-3, HeLa and MOLT-4 cell lines
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  33. Role of Plant-Derived Active Constituents in Cancer Treatment and Their Mechanisms of Action
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  34. Study on the Mechanism of Diosgenin Targeting STAT3 to Inhibit Colon Cancer Proliferation and Migration
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  35. Diosgenin increases BBC3 expression in HepG2/C3A cells and alters cell communication in a 3D spheroid model
    Matheus Felipe da Silva et al, 2022, Mutation Research/Genetic Toxicology and Environmental Mutagenesis CrossRef
  36. Biogenic polymer-encapsulated diosgenin nanoparticles: Biodistribution, pharmacokinetics, cellular internalization, and anticancer potential in breast cancer cells and tumor xenograft
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  37. Synthesis of fully functionalized spirostanic 1,2,3-triazoles by the three component reaction of diosgenin azides with acetophenones and aryl aldehydes and their biological evaluation as antiproliferative agents
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  38. Anticancer Activity of Diosgenin and Its Molecular Mechanism
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  40. Anticancer Potential of Biologically Active Diosgenin and its Derivatives: An Update
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  41. Diosgenin potentiates the anticancer effect of doxorubicin and volasertib via regulating polo-like kinase 1 and triggering apoptosis in hepatocellular carcinoma cells
    Eman H. Yousef et al, 2024, Naunyn-Schmiedeberg's Arch Pharmacol CrossRef
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