1. Deciphering Antitumor Mechanism of Pien Tze Huang in Mice of Hepatocellular Carcinoma Based on Proteomics
    Dancai Fan et al, 2020, Journal of Immunology Research CrossRef
  2. Diosgenin increases BBC3 expression in HepG2/C3A cells and alters cell communication in a 3D spheroid model
    Matheus Felipe da Silva et al, 2022, Mutation Research/Genetic Toxicology and Environmental Mutagenesis CrossRef
  3. Evaluation of antioxidant, anti-inflammatory and anticancer activities of diosgenin enriched Paris polyphylla rhizome extract of Indian Himalayan landraces
    Debmalya Das Gupta et al, 2021, Journal of Ethnopharmacology CrossRef
  4. Diosgenin: an important natural pharmaceutical active ingredient
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  5. Saponins isolated from Schizocapsa plantaginea inhibit human hepatocellular carcinoma cell growth in vivo and in vitro via mitogen-activated protein kinase signaling
    Yue-Wen SUN et al, 2018, Chinese Journal of Natural Medicines CrossRef
  6. Diosgenin exerts its tumor suppressive function via inhibition of Cdc20 in osteosarcoma cells
    Cheng Long et al, 2019, Cell Cycle CrossRef
  7. New selenosteroids as antiproliferative agents
    Alma Fuentes-Aguilar et al, 2017, Organic & Biomolecular Chemistry CrossRef
  8. Estrogen receptor modulators genistein, daidzein and ERB-041 inhibit cell migration, invasion, proliferation and sphere formation via modulation of FAK and PI3K/AKT signaling in ovarian cancer
    Karen K. L. Chan et al, 2018, Cancer Cell International CrossRef
  9. Diosgenin inhibited the expression of TAZ in hepatocellular carcinoma
    Zhize Chen et al, 2018, Biochemical and Biophysical Research Communications CrossRef
  10. Synthesis and potent cytotoxic activity of a novel diosgenin derivative and its phytosomes against lung cancer cells
    Liang Xu et al, 2019, Beilstein Journal of Nanotechnology CrossRef
  11. Diosgenin-based thio(seleno)ureas and triazolyl glycoconjugates as hybrid drugs. Antioxidant and antiproliferative profile
    Laura L. Romero-Hernández et al, 2015, European Journal of Medicinal Chemistry CrossRef
  12. Cytotoxic activity of standardized extracts, a fraction, and individual secondary metabolites from fenugreek seeds against SKOV-3, HeLa and MOLT-4 cell lines
    Justyna Stefanowicz-Hajduk et al, 2021, Pharmaceutical Biology CrossRef
  13. Role of Plant-Derived Active Constituents in Cancer Treatment and Their Mechanisms of Action
    Abdul Waheed Khan et al, 2022, Cells CrossRef
  14. Effect of Diosgenin in Suppressing Viability and Promoting Apoptosis of Human Prostate Cancer Cells: An Interplay with the G Protein-Coupled Oestrogen Receptor?
    Marília I. Figueira et al, 2024, International Journal of Molecular Sciences CrossRef
  15. Comprehensive review on signaling pathways of dietary saponins in cancer cells suppression
    Yifan Zhou et al, 2023, Critical Reviews in Food Science and Nutrition CrossRef
  16. Synthesis of fully functionalized spirostanic 1,2,3-triazoles by the three component reaction of diosgenin azides with acetophenones and aryl aldehydes and their biological evaluation as antiproliferative agents
    Maksim E. Mironov et al, 2023, Steroids CrossRef
  17. Anti-proliferation and anti-migration effects of an aqueous extract of Cinnamomi ramulus on MH7A rheumatoid arthritis-derived fibroblast-like synoviocytes through induction of apoptosis, cell arrest and suppression of matrix metalloproteinase
    Jia Liu et al, 2020, Pharmaceutical Biology CrossRef
  18. Chronic diseases, inflammation, and spices: how are they linked?
    Ajaikumar B. Kunnumakkara et al, 2018, Journal of Translational Medicine CrossRef
  19. The Role of Necroptosis in ROS-Mediated Cancer Therapies and Its Promising Applications
    Sheng-Kai Hsu et al, 2020, Cancers CrossRef
  20. Biogenic polymer-encapsulated diosgenin nanoparticles: Biodistribution, pharmacokinetics, cellular internalization, and anticancer potential in breast cancer cells and tumor xenograft
    Surya Kanta Dey et al, 2022, Journal of Drug Delivery Science and Technology CrossRef
  21. Anticancer Activity of Diosgenin and Its Molecular Mechanism
    Qun-li Ren et al, 2023, Chinese Journal of Integrative Medicine CrossRef
  22. Ginsenoside Rh1 Improves the Effect of Dexamethasone on Autoantibodies Production and Lymphoproliferation in MRL/lpr Mice
    Yinglu Feng et al, 2015, Evidence-Based Complementary and Alternative Medicine CrossRef
  23. Exploring the impact of a naturally occurring sapogenin diosgenin on underlying mechanisms of Ca2+ movement and cytotoxicity in human prostate cancer cells
    Gwo‐Ching Sun et al, 2020, Environmental Toxicology CrossRef
  24. DIOSGENIN AT THE CELLULAR LEVEL AS A CANCER REMEDIAL AGENT
    null null et al, 2023, Indian Drugs CrossRef
  25. Diosgenin-induced autophagy and apoptosis in a human prostate cancer cell line
    Chao Nie et al, 2016, Molecular Medicine Reports CrossRef
  26. Taccaoside induces apoptosis in hepatocellular carcinoma cell lines
    Yuewen Sun et al, 2016, Journal of International Medical Research CrossRef
  27. Identification, Phytochemistry and Biological Activities of Paris polyphylla on Hepatocellular Carcinoma
    Ton Son Bach et al, 2023, Pakistan Journal of Biological Sciences CrossRef
  28. Anticancer activities of phytoconstituents and their liposomal targeting strategies against tumor cells and the microenvironment
    Jing Zhang et al, 2020, Advanced Drug Delivery Reviews CrossRef
  29. Diosgenin-loaded niosome as an effective phytochemical nanocarrier: physicochemical characterization, loading efficiency, and cytotoxicity assay
    Mohammad Reza Hajizadeh et al, 2019, DARU Journal of Pharmaceutical Sciences CrossRef
  30. Assessment of Secondary Metabolites with Different Uses of Fenugreek
    Gulsum Yaldiz et al, 2022, Legumes Research - Volume 2 CrossRef
  31. What Chinese Medicine Can Do for Liver Cancer?
    Feiyu Chen et al, 2018, Liver Cancer CrossRef
  32. Recombinant PEP‑1‑SOD1 improves functional recovery after neural stem cell transplantation in rats with traumatic brain injury
    Jinming Jia et al, 2018, Experimental and Therapeutic Medicine CrossRef
  33. Diosgenin: Recent Highlights on Pharmacology and Analytical Methodology
    Mafalda Jesus et al, 2016, Journal of Analytical Methods in Chemistry CrossRef
  34. Diosgenin potentiates the anticancer effect of doxorubicin and volasertib via regulating polo-like kinase 1 and triggering apoptosis in hepatocellular carcinoma cells
    Eman H. Yousef et al, 2024, Naunyn-Schmiedeberg's Archives of Pharmacology CrossRef
  35. Diosgenyl Saponin Inducing Endoplasmic Reticulum Stress and Mitochondria-Mediated Apoptotic Pathways in Liver Cancer Cells
    Xin Meng et al, 2019, Journal of Agricultural and Food Chemistry CrossRef
  36. Diosgenin, a steroidal saponin, and its analogs: Effective therapies against different chronic diseases
    Dey Parama et al, 2020, Life Sciences CrossRef
  37. 6-(4′-Aryl-1′,2′,3′-triazolyl)-spirostan-3,5-diols and 6-(4′-Aryl-1′,2′,3′-triazolyl)-7-hydroxyspirosta-1,4-dien-3-ones: Synthesis and analysis of their cytotoxicity
    Maxim E. Mironov et al, 2019, Steroids CrossRef
  38. Secondary Metabolites, Antioxidant, and Antiproliferative Activities of Dioscorea bulbifera Leaf Collected from Endau Rompin, Johor, Malaysia
    Muhammad Murtala Mainasara et al, 2021, Evidence-Based Complementary and Alternative Medicine CrossRef
  39. Anticancer Potential of Biologically Active Diosgenin and its Derivatives: An Update
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  40. Role of microRNA-363 during tumor progression and invasion
    Arya Nasimi Shad et al, 2024, Journal of Physiology and Biochemistry CrossRef
  41. Autophagy plays a pro-apoptotic role in arsenic trioxide-induced cell death of liver cancer
    Zheng-ting Deng et al, 2024, Journal of Integrative Medicine CrossRef
  42. Diosgenin induces genotoxic and mutagenic effects on HepG2 cells
    Marina Sampaio Cruz et al, 2018, Food and Chemical Toxicology CrossRef
  43. Study on the Mechanism of Diosgenin Targeting STAT3 to Inhibit Colon Cancer Proliferation and Migration
    Zonglang Lai et al, 2022, Disease Markers CrossRef
  44. Diosgenin Mitigates Streptozotocin Diabetes-induced Vascular Dysfunction of the Rat Aorta
    Farshad Roghani-Dehkordi et al, 2015, Journal of Cardiovascular Pharmacology CrossRef
  45. miR-363-3p inhibits tumor growth by targeting PCNA in lung adenocarcinoma
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