1. Identification of Sphingosine Kinase-1 Inhibitors from Bioactive Natural Products Targeting Cancer Therapy
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  2. The Tumorigenic Effect of Sphingosine Kinase 1 and Its Potential Therapeutic Target
    Xianwang Wang et al, 2020, Cancer Control CrossRef
  3. Regulation of Autophagy via Carbohydrate and Lipid Metabolism in Cancer
    Javad Alizadeh et al, 2023, Cancers CrossRef
  4. A novel oncolytic adenovirus inhibits hepatocellular carcinoma growth
    Yu-huan Bai et al, 2019, Journal of Zhejiang University-SCIENCE B CrossRef
  5. GDC-0349 inhibits non-small cell lung cancer cell growth
    Han Yang et al, 2020, Cell Death & Disease CrossRef
  6. lncRNA KHPS1 Activates a Poised Enhancer by Triplex-Dependent Recruitment of Epigenomic Regulators
    Alena Blank-Giwojna et al, 2019, Cell Reports CrossRef
  7. Sphingosine kinase�1 promotes the metastasis of colorectal cancer by inducing the epithelial‑mesenchymal transition mediated by the FAK/AKT/MMPs axis
    Shi‑Quan Liu et al, 2018, International Journal of Oncology CrossRef
  8. Targeting sphingosine kinase 1/2 by a novel dual inhibitor SKI-349 suppresses non-small cell lung cancer cell growth
    Yuhang Xue et al, 2022, Cell Death & Disease CrossRef
  9. “Dicing and Splicing” Sphingosine Kinase and Relevance to Cancer
    Nahal Haddadi et al, 2017, International Journal of Molecular Sciences CrossRef
  10. Evaluation of ellagic acid as an inhibitor of sphingosine kinase 1: A targeted approach towards anticancer therapy
    Preeti Gupta et al, 2019, Biomedicine & Pharmacotherapy CrossRef
  11. Sphk1 promotes breast epithelial cell proliferation via NF-κB-p65-mediated cyclin D1 expression
    Shifei Li et al, 2016, Oncotarget CrossRef
  12. Sphingosine Kinase 1 Signaling in Breast Cancer: A Potential Target to Tackle Breast Cancer Stem Cells
    Ling-Wei Hii et al, 2021, Frontiers in Molecular Biosciences CrossRef
  13. Investigation of guanidinium chloride-induced unfolding pathway of sphingosine kinase 1
    Preeti Gupta et al, 2020, International Journal of Biological Macromolecules CrossRef
  14. Discovery of Harmaline as a Potent Inhibitor of Sphingosine Kinase-1: A Chemopreventive Role in Lung Cancer
    Sonam Roy et al, 2020, ACS Omega CrossRef
  15. Sphingolipid Metabolism and Signaling in Lung Cancer: A Potential Therapeutic Target
    Mengmeng Lin et al, 2022, Journal of Oncology CrossRef
  16. SphK1 promotes tumor cell migration and invasion in colorectal cancer
    Jianting Long et al, 2016, Tumor Biology CrossRef
  17. Overexpression of SphK1 enhances cell proliferation and invasion in triple-negative breast cancer via the PI3K/AKT signaling pathway
    Jun Li et al, 2016, Tumor Biology CrossRef
  18. Upregulation of sphingosine kinase 1 in response to doxorubicin generates an angiogenic response via stabilization of Snail
    Joseph Bonica et al, 2023, The FASEB Journal CrossRef
  19. MicroRNA-124 upregulation inhibits proliferation and invasion of osteosarcoma cells by targeting sphingosine kinase 1
    Yan Zhou et al, 2016, Human Cell CrossRef
  20. Design, synthesis and biological evaluation of novel benzimidazole amidines as potent multi-target inhibitors for the treatment of non-small cell lung cancer
    Andrea Bistrović et al, 2018, European Journal of Medicinal Chemistry CrossRef
  21. Integration of metabolites from meta-analysis with transcriptome reveals enhanced SPHK1 in PDAC with a background of pancreatitis
    Vijayasarathy Ketavarapu et al, 2022, BMC Cancer CrossRef
  22. Mammalian sphingosine kinase (SphK) isoenzymes and isoform expression: challenges for SphK as an oncotarget
    Diana Hatoum et al, 2017, Oncotarget CrossRef
  23. SGPL1321 mutation: one main trigger for invasiveness of pediatric alveolar rhabdomyosarcoma
    Anna Adamus et al, 2020, Cancer Gene Therapy CrossRef
  24. The Anti-Non-Small Cell Lung Cancer Cell Activity by a mTOR Kinase Inhibitor PQR620
    Jian-hua Zha et al, 2021, Frontiers in Oncology CrossRef