- Targeting ATR in cancer
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Ryan C. Leibrandt et al, 2023, Clinical Genitourinary Cancer CrossRef - ATM Inhibitor Suppresses Gemcitabine-Resistant BTC Growth in a Polymerase θ Deficiency-Dependent Manner
Yi-Ru Pan et al, 2020, Biomolecules CrossRef - The ATR Inhibitor AZD6738 Synergizes with Gemcitabine In Vitro and In Vivo to Induce Pancreatic Ductal Adenocarcinoma Regression
Yann Wallez et al, 2018, Molecular Cancer Therapeutics CrossRef - DNA damage checkpoint kinases in cancer
Hannah L. Smith et al, 2020, Expert Reviews in Molecular Medicine CrossRef - Synergistic anticancer activity of combined ATR and ribonucleotide reductase inhibition in Ewing's sarcoma cells
Max-Johann Sturm et al, 2023, Journal of Cancer Research and Clinical Oncology CrossRef - Effects of CXCL12 isoforms in a pancreatic pre-tumour cellular model: Microarray analysis
Monia Cecati et al, 2021, World Journal of Gastroenterology CrossRef - DNA damage response revisited: the p53 family and its regulators provide endless cancer therapy opportunities
Yasser Abuetabh et al, 2022, Experimental & Molecular Medicine CrossRef - Inhibition of ATR acutely sensitizes acute myeloid leukemia cells to nucleoside analogs that target ribonucleotide reductase
Sarah E. Fordham et al, 2018, Blood Advances CrossRef - A Replication stress biomarker is associated with response to gemcitabine versus combined gemcitabine and ATR inhibitor therapy in ovarian cancer
Panagiotis A. Konstantinopoulos et al, 2021, Nature Communications CrossRef - Berzosertib plus gemcitabine versus gemcitabine alone in platinum-resistant high-grade serous ovarian cancer: a multicentre, open-label, randomised, phase 2 trial
Panagiotis A Konstantinopoulos et al, 2020, The Lancet Oncology CrossRef - Key Proteins of Replication Stress Response and Cell Cycle Control as Cancer Therapy Targets
Alvina I. Khamidullina et al, 2024, International Journal of Molecular Sciences CrossRef - Exploiting DNA Replication Stress for Cancer Treatment
Tajinder Ubhi et al, 2019, Cancer Research CrossRef - Therapeutic resistance of pancreatic cancer: Roadmap to its reversal
Sen Yu et al, 2021, Biochimica et Biophysica Acta (BBA) - Reviews on Cancer CrossRef - Targeting replication stress in cancer therapy
Alexandre André B. A. da Costa et al, 2023, Nature Reviews Drug Discovery CrossRef - Effect of Cisplatin and Gemcitabine With or Without Berzosertib in Patients With Advanced Urothelial Carcinoma
Sumanta K. Pal et al, 2021, JAMA Oncology CrossRef - Inhibition of Wee1 sensitizes AML cells to ATR inhibitor VE-822-induced DNA damage and apoptosis
Wenxiu Qi et al, 2019, Biochemical Pharmacology CrossRef - Fisetin inhibits proliferation of pancreatic adenocarcinoma by inducing DNA damage via RFXAP/KDM4A-dependent histone H3K36 demethylation
Guoping Ding et al, 2020, Cell Death & Disease CrossRef - Glutamine deprivation counteracts hypoxia-induced chemoresistance
Jessica Wappler et al, 2020, Neoplasia CrossRef - Randomized Phase II Study of Gemcitabine With or Without ATR Inhibitor Berzosertib in Platinum-Resistant Ovarian Cancer: Final Overall Survival and Biomarker Analyses
Panagiotis A. Konstantinopoulos et al, 2024, JCO Precision Oncology CrossRef