TY - JOUR AB - Mycoplasma pneumoniae plays an important role in community-acquired pneumonia. However, epidemiological and clinical studies on the segmental/lobar pattern (S/L) radiographic‑pathologic subtype of pediatric Mycoplasma pneumoniae pneumonia (MPP) are rare. The current study retrospectively analyzed the epidemiological and clinical characteristics of pediatric MPP patients. A total of 1,933 children with MPP received treatment at a single hospital between 2000 and 2009, of which 684 (35.4%) were diagnosed with S/L‑MPP. The annual incidence of S/L‑MPP in children with MPP increased throughout the duration of this study (from 6.4 to 59.6%, P<0.001), which was particularly evident after 2003. S/L‑MPP was predominantly found in pre‑school‑aged children (4‑6 years old; 56.6%). Compared with non‑S/L‑MPP, S/L‑MPP was more closely associated with severe manifestations, including higher rates of fever (90.2 vs. 83.3%), pleural effusion (3.9 vs. 1.3%), extrapulmonary manifestations (26.2 vs. 21.2%), abnormal white blood cell counts (65.5 vs. 55.2%), abnormal C‑reactive protein levels (30.9 vs. 23.7%) and bacterial co‑infection (32.0 vs. 24.9%), as well as longer durations of fever (4.13±4.28 vs. 3.02±2.22 days) and hospitalization (12.70±4.54 vs. 9.22±5.12 days). Older S/L‑MPP patients showed higher rates and longer durations of fever and cough; however, they also displayed a lower rate of extrapulmonary manifestations when compared with younger patients. In conclusion, the annual incidence of S/L‑MPP has increased in recent years. Pre-school-aged children (4‑6 years) with MPP are more likely to display a segmental/lobar pattern, which is associated with more severe clinical manifestations than other MPP infection patterns. AD - Department of Pediatrics, Weifang Maternal and Child Health Hospital, Weifang, Shandong 261011, P.R. China Pulmonary Department, Weifang Chest Hospital, Weifang, Shandong 261011, P.R. China Department of Neonatology, Children's Hospital of Fudan University, Shanghai 201102, P.R. China AU - Gao,Jian AU - Yue,Baozhu AU - Li,Haitao AU - Chen,Rong AU - Wu,Chunlian AU - Xiao,Mili DA - 2015/12/01 DO - 10.3892/etm.2015.2818 EP - 2344 IS - 6 JO - Exp Ther Med KW - children epidemiology Mycoplasma pneumoniae pneumonia segmental and/or lobar PY - 2015 SN - 1792-0981 1792-1015 SP - 2337 ST - Epidemiology and clinical features of segmental/lobar pattern Mycoplasma pneumoniae pneumonia: A ten-year retrospective clinical study T2 - Experimental and Therapeutic Medicine TI - Epidemiology and clinical features of segmental/lobar pattern Mycoplasma pneumoniae pneumonia: A ten-year retrospective clinical study UR - https://doi.org/10.3892/etm.2015.2818 VL - 10 ER -