TY - JOUR AB - The present study reports an unusual case of high‑grade bladder cancer in a 10‑year‑old girl who complained of painless hematuria and urinary frequency. The tumor displayed sarcomatoid differentiation and an aggressive behavior, which required the administration of adjuvant chemotherapy. However, the disease progressed and the patient succumbed 6 months after surgery. It is known that the majority of malignant bladder cancers in pediatric patients are low‑grade and present at an early stage, whereas sarcomatoid differentiation in the setting of a high‑grade urothelial carcinoma is indicative of a poor prognosis. It is important that gross hematuria in pediatric patients is investigated carefully. It is recommended that the management of urothelial neoplasia in young patients should be predominantly decided on the basis of the grade and stage of the tumor rather than the age of the patient. AD - Department of Urology, The Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, P.R. China AU - Wang,Zijian AU - Xiong,Wei AU - Pan,Cizhong AU - Zhu,Liang AU - Wang,Xinjun AU - Huang,Zhichao AU - Zhao,Xiaokun AU - Zhong,Zhaohui DA - 2016/03/01 DO - 10.3892/etm.2016.3012 EP - 987 IS - 3 JO - Exp Ther Med KW - bladder cancer radical cystectomy adjuvant therapy children PY - 2016 SN - 1792-0981 1792-1015 SP - 985 ST - Aggressive muscle‑invasive bladder cancer with sarcomatoid differentiation in a 10‑year‑old girl: A case report T2 - Experimental and Therapeutic Medicine TI - Aggressive muscle‑invasive bladder cancer with sarcomatoid differentiation in a 10‑year‑old girl: A case report UR - https://doi.org/10.3892/etm.2016.3012 VL - 11 ER -