TY - JOUR AB - Epicardial movement during diastole is inversely proportional to myocardial stiffness but systolic regional thickening cannot precisely identify ischemic territories. The aim of the present study was to test the hypothesis that a correlation may be present between M‑mode echocardiography parameters and poor outcomes in patients with heart failure and preserved ejection fraction. Patients with known cardiovascular disease were included in the test group (n=1,244) and patients without known cardiovascular disease were included in the control group (n=1,952). Patient records of routine measurements, M‑mode echocardiography and mortality were collected. The control population and test population had the same left ventricular end‑diastolic dimension (P=0.062) and left ventricular end‑diastolic volume (P=0.053). A lower mitral flow velocity (P<0.05), higher Tei index (P<0.0001) and reduced distribution of diastolic wall strain (P<0.0001) were reported in the test populations compared with the control population. Patients of the test population with lower diastolic wall strain (<0.28) demonstrated a higher mortality rate than those with higher diastolic wall strain (≥0.28; P<0.0001) at the 3‑year follow‑up. M‑mode echocardiographic parameters may be of use for predicting poor outcomes in patients with heart failure and preserved ejection fraction. AD - Department of Cardiovascular Medicine, Cardiovascular Research Institute, Affiliated Dongfeng Hospital, Hubei University of Medicine, Shiyan, Hubei 442008, P.R. China AU - Li,Xin AU - Min,Xinwen DA - 2020/03/01 DO - 10.3892/etm.2020.8428 EP - 1976 IS - 3 JO - Exp Ther Med KW - diastolic wall strain ejection fraction heart failure mitral flow velocity M‑mode echocardiography PY - 2020 SN - 1792-0981 1792-1015 SP - 1969 ST - The role of M‑mode echocardiography in patients with heart failure and preserved ejection fraction: A prospective cohort study T2 - Experimental and Therapeutic Medicine TI - The role of M‑mode echocardiography in patients with heart failure and preserved ejection fraction: A prospective cohort study UR - https://doi.org/10.3892/etm.2020.8428 VL - 19 ER -