TY - JOUR AB - A case is presented of a male with drug rash with eosinophilia and systemic symptoms (DRESS) syndrome induced by carbamazepine intake. The patient presented all the elements of DRESS syndrome: Skin reaction, fever, enlargement of the lymph nodes, increased eosinophils and lymphocytes, with associated organ dysfunctions. The patient was admitted with acute laryngeal edema and imminence of respiratory insufficiency. The escalation of symptoms for this syndrome is typical, even after the administering of the the culprit medicine has ceased. However, in this case, the most difficult aspect was the complex treatment scheme prior to admission. All medical compounds involved in the background treatment were substituted with other substances in order to control the immune response. Current knowledge regarding DRESS is reviewed and possible influence of various etiologies over the present case are discussed. Clinicians should be aware of this rare situation with life-threatening potential. We benefited from the advantage of reuniting the knowledge of a complex team of experts from various tertiary emergency units in Romania. AD - ENT Department, Bucharest Emergency University Hospital, 010271 Bucharest, Romania Department of Anatomy, ‘Carol Davila’ University of Medicine and Pharmacy, 050474 Bucharest, Romania ENT Department, Târgu Mureș University of Medicine and Pharmacy, 540139 Târgu Mureș, Romania ENT Department, ‘Sânta Maria’ Clinical Hospital, 011172 Bucharest, Romania Department of Anesthesia and ICU, Bucharest Emergency University Hospital, 020021 Bucharest, Romania AU - Vrinceanu,Daniela AU - Dumitru,Mihai AU - Stefan,Adrian AU - Neagos,Adriana AU - Musat,Gabriela AU - Nica,Elena ,Adriana DA - 2020/09/01 DO - 10.3892/etm.2020.8894 EP - 2380 IS - 3 JO - Exp Ther Med KW - DRESS syndrome eosinophilia respiratory distress carbamazepine addiction PY - 2020 SN - 1792-0981 1792-1015 SP - 2377 ST - Severe DRESS syndrome after carbamazepine intake in a case with multiple addictions: A case report T2 - Experimental and Therapeutic Medicine TI - Severe DRESS syndrome after carbamazepine intake in a case with multiple addictions: A case report UR - https://doi.org/10.3892/etm.2020.8894 VL - 20 ER -