TY - JOUR AB - Flexible ureteroscopy lithotripsy (FURS) is the most common treatment for patients with upper urinary tract calculi (diameter, <2 cm). The purpose of this prospective study was to assess the efficacy of FURS combined with metallic ureteral stents (MUS) for the treatment of upper urinary tract calculi. A total of 38 patients with upper urinary tract calculi were recruited in the present study, to compare the efficacy between FURS and FURS combined with MUS (FURS‑MUS). The results demonstrated that FURS‑MUS shortened operative time compared with FURS (35.2±1.2 vs. 57.4±1.7 min, respectively; P<0.01). Data also indicated that the clearance rate in FURS‑MUS and FURS was decreased from 94.5 and 87.8%, respectively (P<0.05). FURS‑MUS treatment decreased the duration of postoperative hospital stay compared with FURS (4.5±0.5 vs. 7.5±1.5 days, respectively; P<0.05). These data demonstrated that FURS‑MUS significantly increased postoperative inflammation score compared with FURS (6.2±0.8 vs. 4.2±1.0, respectively; P<0.05). The complication rate and blood loss exhibited no significant difference between FURS‑MUS and FURS (complication rate, 6.5% vs. 5.9%, respectively; blood loss, 4.2% vs. 4.6%, respectively). FURS‑MUS significantly decreased inflammatory cytokines and risk of sepsis, and improved readmission rate, stone recurrence and progression‑free survival compared with patients treated with FURS. In conclusion, these data suggested that FURS‑MUS may be an efficient, minimally invasive and reproducible operation for patients with upper urinary tract calculi. AD - Department of Urology, The Fifth Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong 510700, P.R. China Department of Urology, The First Affiliated Hospital of Sun Yat‑Sen University, Guangzhou, Guangdong 510080, P.R. China AU - Li,Tian AU - Sun,Xiangzhou AU - Li,Xun AU - He,Yongzhong DA - 2020/10/01 DO - 10.3892/etm.2020.9038 EP - 3335 IS - 4 JO - Exp Ther Med KW - flexible ureteroscopy lithotripsy with metallic ureteral stents upper urinary tract calculi inflammation readmission rate stone recurrence PY - 2020 SN - 1792-0981 1792-1015 SP - 3330 ST - Flexible ureteroscopy lithotripsy combined with metallic ureteral stents for the treatment of patients with upper urinary tract calculi T2 - Experimental and Therapeutic Medicine TI - Flexible ureteroscopy lithotripsy combined with metallic ureteral stents for the treatment of patients with upper urinary tract calculi UR - https://doi.org/10.3892/etm.2020.9038 VL - 20 ER -