TY - JOUR AB - Dental erosion is a significant topic in medical literature, both for gastroenterology and dental medicine. Dental structure loss has a psychosocial and functional significance. The pathogenesis of dental erosion in patients diagnosed with gastroesophageal reflux disease (GERD) characterized by the presence of an acidic oral environment after reflux episodes, is not well understood. The present study was designed to observe the effect of low oral pH in time on natural surfaces including enamel and dentine, but also on materials used in treating these dental destructions such as composites and ceramics. The acidic oral environment was estimated in relation to salivary pH. In the dental laboratory, 5‑mm2 and 1‑mm composite pieces of thick enamel, dentine, Emax Ceramic and Nexco Ivoclar were cut in order to be analyzed using atomic force microscopy (AFM) and to observe the surface alterations. Gastric acid was collected and mixed with saliva until a pH value of 6.0 was obtained, in which the pieces were immersed for 24, 120, 240 h. Roughness of each surface was calculated at a microstructure and nanostructure level. The results showed significant alterations in enamel and dentine exposed to a lower pH level beginning even at a short immersion time, in comparison with composites and ceramics which had no alterations. In conclusion, multidisciplinary attention should be given to detect and manage acidity of the oral cavity caused by GERD, in order to prevent dental erosion. AD - Department of Dental Prosthetics, ‘Iuliu Haţieganu’ University of Medicine and Pharmacy, 400000 Cluj‑Napoca, Romania Faculty of Chemistry and Chemical Engineering, ‘Babes Bolyai’ University, 400028 Cluj‑Napoca, Romania Department of Prevention in Dental Medicine, ‘Iuliu Haţieganu’ University of Medicine and Pharmacy, 400000 Cluj‑Napoca, Romania Department of Cardiology ‘Nicolae Stancioiu’ Heart Institute, ‘Iuliu Haţieganu’ University of Medicine and Pharmacy, 400000 Cluj‑Napoca, Romania Department of Pediatrics II, ‘Iuliu Haţieganu’ University of Medicine and Pharmacy, 400000 Cluj‑Napoca, Romania Second Department of Internal Medicine, ‘Iuliu Haţieganu’ University of Medicine and Pharmacy, 400000 Cluj‑Napoca, Romania ArtChrys Dental Laboratory, 400664 Cluj‑Napoca, Romania Department Photo‑Video, University of Arts and Design, 400148 Cluj‑Napoca, Romania AU - Picoș,Alina,Monica AU - Petean,Ioan AU - Picoș,Andrei AU - Dădârlat‑Pop,Alexandra AU - Răchișan,Andreea-Liana AU - Tomșa,Anamaria,Magdalena AU - Petrăchescu,Narcisa,Mădălina AU - Petri,Cristian AU - Badea,Mândra,Eugenia AU - Măgurean,Irina,Dora DA - 2021/07/01 DO - 10.3892/etm.2021.10105 IS - 1 JO - Exp Ther Med KW - atomic force microscopy e.max ceramic composite dentine enamel gastroesophageal reflux disease dental erosion PY - 2021 SN - 1792-0981 1792-1015 SP - 673 ST - Atomic force microscopy analysis of the surface alterations of enamel, dentin, composite and ceramic materials exposed to low oral pH in GERD T2 - Experimental and Therapeutic Medicine TI - Atomic force microscopy analysis of the surface alterations of enamel, dentin, composite and ceramic materials exposed to low oral pH in GERD UR - https://doi.org/10.3892/etm.2021.10105 VL - 22 ER -