TY - JOUR AB - Several neurological complications affecting the central and peripheral nervous system were described secondary to COVID‑19 infection such as hyposmia, headache, nausea, impaired consciousness, psychosis, neurocognitive syndromes and even cerebrovascular accidents. The mechanism of these complications is not fully understood, but heterogenous mechanisms such as cytokine storm, secondary hypercoagulability and direct neurotropism of the virus are thought to be involved. Guillain‑Barré syndrome is a heterogeneous disease that frequently follows a bacterial or viral infection. During the ongoing SARS‑CoV‑2 pandemic, several isolated case reports and case series have suggested an association between this viral infection and the occurrence of Guillain‑Barré syndrome. The main mechanism of Guillain‑Barré syndrome is probably post‑viral dysregulation of the immune system generated by SARS‑CoV‑2. The clinical characteristics and disease evolution seem to be similar to those observed in Guillain‑Barré syndrome secondary to other etiologies. The aim of the present review is to summarize the relevant literature regarding SARS‑CoV‑2‑related Guillain‑Barré syndrome. AD - Department of Pathophysiology, ‘George Emil Palade’ University of Medicine, Pharmacy, Science and Technology, 540136 Targu Mures, Romania Department of Neurology, ‘George Emil Palade’ University of Medicine, Pharmacy, Science and Technology, 540136 Targu Mures, Romania Department of Neurology, ‘George Emil Palade’ University of Medicine, Pharmacy, Sciences and Technology, 540136 Targu Mures, Romania Department of Neurology, 1st Neurology Clinic, Mures County Clinical Emergency Hospital, 540136 Targu Mures, Romania Department of Interventional Radiology, Mures County Clinical Emergency Hospital, 540136 Targu Mures, Romania Department of Anesthesiology and Intensive Therapy, ‘George Emil Palade’ University of Medicine, Pharmacy, Science and Technology, 540136 Targu Mures, Romania AU - Stoian,Adina AU - Bălașa,Rodica AU - Grigorescu,Bianca,Liana AU - Maier,Smaranda AU - Andone,Sebastian AU - Cocuz,Iuliu,Gabriel AU - Bajko,Zoltan AU - Filep,Cristian,Rares AU - Stoian,Mircea DA - 2021/09/01 DO - 10.3892/etm.2021.10348 IS - 3 JO - Exp Ther Med KW - Guillain‑Barré syndrome COVID‑19 neurological complications AMAN tetraparesis SARS‑CoV‑2 PY - 2021 SN - 1792-0981 1792-1015 SP - 916 ST - Guillain‑Barré syndrome associated with Covid‑19: A close relationship or just a coincidence? (Review) T2 - Experimental and Therapeutic Medicine TI - Guillain‑Barré syndrome associated with Covid‑19: A close relationship or just a coincidence? (Review) UR - https://doi.org/10.3892/etm.2021.10348 VL - 22 ER -