TY - JOUR AB - Stroke is one of the leading causes of mortality globally and a main cause of disability. The objective of this study was to evaluate the importance and utility of the Alberta Stroke Program Early CT Score (ASPECTS) as a mortality predictor factor in diabetic vs. non‑diabetic patients with acute ischemic stroke (AIS), correlated with age, monocyte values, and high‑sensitivity cardiac troponin I (hs‑cTnI). The prospective longitudinal observational study included 340 patients with AIS divided into two groups: diabetics and non‑diabetics. ASPECTS was evaluated within the first 24 h after admission to the center. The ASPECTS was lower in the group of diabetic patients on average 4.9 vs. 6.05 (P<0.0001). As the age of the patients increased, the lower the ASPECTS and the higher infarct size, indicating a statistically significant (P<0.0001) result. The optimal correlation was observed between infarct size (ASPECTS) and hs‑cTnI serum level [95% confidence interval (CI): ‑0.3216 to ‑0.1193; P<0.0001]. Almost 94% of patients who had an ASPECTS higher than 3 points on admission survived, resulting in a favorable outcome and a very good predictability of the score (95% CI: 0.85 to 0.926, P<0.0001). The ASPECTS is a mortality predictor, its value correlating inversely with the severity and evolution of patients, confirming a good predictability with good specificity, sensitivity and area under the curve. AD - Department of Surgical Disciplines, Faculty of Medicine and Pharmacy, University of Oradea, 410073 Oradea, Romania Department of Pharmacy, Faculty of Medicine and Pharmacy, University of Oradea, 410073 Oradea, Romania Department 5, ‘Carol Davila’ University of Medicine and Pharmacy, 050474 Bucharest, Romania Department of Medical Disciplines, Faculty of Medicine and Pharmacy, University of Oradea, 410073 Oradea, Romania AU - Pop,Nicolae,Ovidiu AU - Tit,Delia,Mirela AU - Diaconu,Camelia,Cristina AU - Munteanu,Mihai,Alexandru AU - Babes,Emilia,Elena AU - Stoicescu,Manuela AU - Popescu,Mircea,Ioachim AU - Bungau,Simona DA - 2021/12/01 DO - 10.3892/etm.2021.10805 IS - 6 JO - Exp Ther Med KW - ischemic stroke diabetes ASPECTS high‑sensitivity troponin I mortality PY - 2021 SN - 1792-0981 1792-1015 SP - 1371 ST - The Alberta Stroke Program Early CT score (ASPECTS): A predictor of mortality in acute ischemic stroke T2 - Experimental and Therapeutic Medicine TI - The Alberta Stroke Program Early CT score (ASPECTS): A predictor of mortality in acute ischemic stroke UR - https://doi.org/10.3892/etm.2021.10805 VL - 22 ER -