TY - JOUR AB - Psoriasis is a chronic inflammatory and immune‑mediated condition, which is no longer considered as being limited to the skin, but may affect the entire body. Epidemiological studies have shown that certain disorders, including obesity, diabetes, liver abnormalities, elevated lipid levels in the blood and metabolic syndrome, may occur more frequently in patients with psoriasis compared with the general population. As psoriasis is a chronic disease, the frequently associated comorbidities must be identified early to ensure timely treatment and, possibly, their prevention. Comorbidities often manifest clinically 1‑2 years after the onset of psoriasis and are commonly seen in patients with severe forms of the disease. The association between psoriasis and its comorbidities is not coincidental, but rather based on common pathophysiological mechanisms and risk factors that underlie the increased frequency of comorbidities in patients with psoriasis. The aim of the present review was to emphasize the important role of dermatologists in the early recognition of comorbidities in patients with psoriasis, with a focus on metabolic comorbidities, precisely because the dermatologists are usually the first medical contact due to the predominance of skin lesions. Therefore, these specialists have the responsibility to inform patients on the association between psoriasis and possible multiple comorbidities, devise prevention and treatment plans, or even redirect patients to other specialists. AD - Department of Dermatology, ‘Grigore T. Popa’ University of Medicine and Pharmacy, 700115 Iasi, Romania Department of Ophthalmology, ‘Carol Davila’ University of Medicine and Pharmacy, 050474 Bucharest, Romania Department of Dermatology, Railway Clinical Hospital, 700506 Iasi, Romania Department of Dermatology, ‘Sf. Spiridon’ Clinical Emergency County Hospital, 700111 Iasi, Romania Department of Dermatology, ‘Roma’ Medical Center for Diagnosis and Treatment, 011773 Bucharest, Romania Department of Ophthalmology, ‘Grigore T. Popa’ University of Medicine and Pharmacy, 700115 Iasi, Romania Faculty of Medicine, ‘Grigore T. Popa’ University of Medicine and Pharmacy, 700115 Iasi, Romania Department of Dermatology, ‘Arcadia’ Hospitals and Medical Centers, 700620 Iasi, Romania Department of Oral Dermatology, ‘Grigore T. Popa’ University of Medicine and Pharmacy, 700115 Iasi, Romania AU - Branisteanu,Daciana,Elena AU - Pirvulescu,Ruxandra,Angela AU - Spinu,Alina,Elena AU - Porumb,Elena,Andrese AU - Cojocaru,Mihaela AU - Nicolescu,Alin,Codrut AU - Branisteanu,Daniel,Constantin AU - Branisteanu,Catalina,Ioana AU - Dimitriu,Andreea AU - Alexa,Anisia,Iuliana AU - Toader,Mihaela,Paula DA - 2022/02/01 DO - 10.3892/etm.2021.11102 IS - 2 JO - Exp Ther Med KW - psoriasis metabolic comorbidities management obesity diabetes mellitus dyslipidemia metabolic syndrome PY - 2022 SN - 1792-0981 1792-1015 SP - 179 ST - Metabolic comorbidities of psoriasis (Review) T2 - Experimental and Therapeutic Medicine TI - Metabolic comorbidities of psoriasis (Review) UR - https://doi.org/10.3892/etm.2021.11102 VL - 23 ER -