TY - JOUR AB - As it spread globally, the new SARS‑CoV‑2 virus was first confirmed in Romania in February 2020, inevitably infecting individuals with diabetes mellitus (DM) along the way. Diabetes is known to affect the response of the body to pathogens and, according to studies conducted in the last 3 months, it appears that diabetic patients are at a higher risk for developing severe forms of the disease and multiple complications. We performed a retrospective study in order to assess the patients with SARS‑CoV‑2 infection and DM admitted to ‘Sf. Parascheva’ Clinical Hospital of Infectious Diseases from March 4th until June 30th, 2020. Of the total 1,080 patients admitted during this period, 85 patients (7.87%) had underlying DM, mostly type 2 (82 cases, 96.46%); the mean age of these patients was 62, and 42 were men (49.41%). Chest CTs revealed indicative SARS‑CoV‑2 images for all patients and their treatment included individually tailored administration of hydroxychloroquine/lopinavir + ritonavir/enoxaparin sodium/tocilizumab/antibiotherapy according to the then national and international guidelines. In total, 70 patients (82.35%) were cured and 15 succumbed to MODS and/or associated neoplasia, bringing the fatality rate to 17.64%. Although advanced age and DM have been associated with aggravated forms of SARS‑CoV‑2 infection, over 80% of the patients included in the present study were cured. Nonetheless, diabetes appears to be a significant predictor of morbidity and mortality in the SARS‑CoV‑2 infection. AD - Department of Infectious Diseases, University of Medicine and Pharmacy ‘Grigore T. Popa’, 700115 Iasi, Romania Department of Obstetrics and Gynecology, University of Medicine and Pharmacy ‘Grigore T. Popa’, 700115 Iasi, Romania Department of Infectious Diseases, ‘Sf. Parascheva’ Clinical Hospital of Infectious Diseases, 700116 Iasi, Romania AU - Manciuc,Carmen AU - Nemescu,Dragos AU - Vata,Andrei AU - Lacatusu,Georgiana,Alexandra DA - 2021/03/01 DO - 10.3892/etm.2021.9710 IS - 3 JO - Exp Ther Med KW - SARS‑CoV‑2 diabetes mellitus intensive care unit glycemic level C reactive protein fatality rate PY - 2021 SN - 1792-0981 1792-1015 SP - 279 ST - SARS‑CoV‑2 infection and diabetes mellitus: A North Eastern Romanian experience T2 - Experimental and Therapeutic Medicine TI - SARS‑CoV‑2 infection and diabetes mellitus: A North Eastern Romanian experience UR - https://doi.org/10.3892/etm.2021.9710 VL - 21 ER -