TY - JOUR
AB - Human helminth zoonosis is one of the most encountered helminthiases worldwide. Representative diseases include Toxocara canis and Toxocara cati, which are common nematodes prevalent in dogs and cats. The infiltration of these roundworms in the human body through contaminated food or nematode eggs could lead to central nervous system injury as the roundworms can cross the blood‑brain barrier leading to neurotoxocariasis. Among the neurological and neuropsychological disturbances produced by Toxocara infection, in humans, the most representative are meningitis, encephalitis, myelitis and cerebral vasculitis, but asymptomatic central nervous system infection is probably the most prevalent. The present review examines the clinical symptomatology of neurotoxocariasis in case reports in the literature in the last 7 decades (1950‑2020). The available evidence was retrieved from PubMed and Medline electronic databases. The present review reports the most prevalent clinical symptomatology in the cases of detected and diagnosed Toxocara infection with neuroinvasion. Thus, the present review aims to raise the awareness of neurological cases of Toxocara infection with the potential to at least establish differential diagnosis of neurotoxocariasis.
AD - Department of Neurology, Faculty of General Medicine, ‘Ovidius’ University of Constanta, 900470 Constanta, Romania
Department of Neurology, Faculty of General Medicine, ‘Victor Babes’ University of Medicine and Pharmacy, Timisoara, 300041 Timisoara, Romania
Department of Anatomy, Faculty of General Medicine, ‘Victor Babes’ University of Medicine and Pharmacy, Timisoara, 300041 Timisoara, Romania
Department of Sports, Faculty of Physical Education and Sports, ‘Ovidius’ University of Constanta, 900470 Constanta, Romania
AU - Axelerad,Any,Docu
AU - Stroe,Alina,Zorina
AU - Gogu,Anca,Elena
AU - Pusztai,Agneta
AU - Jianu,Dragos,Catalin
AU - Daniel,Duta
AU - Axelerad,Daniel,Docu
DA - 2021/05/01
DO - 10.3892/etm.2021.9953
IS - 5
JO - Exp Ther Med
KW - Toxocara canis
Toxocara catis
neuroinvasion
neurotoxocariasis
nervous system
PY - 2021
SN - 1792-0981
1792-1015
SP - 521
ST - Clinical spectrum of symptoms in cerebral Toxocariasis (Review)
T2 - Experimental and Therapeutic Medicine
TI - Clinical spectrum of symptoms in cerebral Toxocariasis (Review)
UR - https://doi.org/10.3892/etm.2021.9953
VL - 21
ER -