TY - JOUR AB - The complex manifestations of COVID‑19 include psychiatric symptoms, having multifaceted profiles with varying severity during the acute phase and further during the recovery period. Limited data exist which have analyzed whether there are any age‑related differences. A study lot of 89 COVID‑19 patients with mild‑to‑moderate SARS‑CoV‑2 infection requiring hospitalization for mental issues provided comparative data from two age groups below and above 60 years. The majority of patients had new onset of a mental issue during COVID‑19, 24.7% of the total lot being diagnosed with depressive disorder. The senior patient set had a significantly higher prevalence of sleep disorder vs. the younger study group (53.3 vs. 28.8%), depression (33.3 vs. 10.2%) and cognitive impairment (26.7 vs. 8.5%), while patients <60 years of age had a higher prevalence of hallucinations, delirium and bizarre behavior. Psychiatric manifestations are an important part of the symptomatology of COVID‑19, sometimes requiring hospitalization. Age‑related neuropsychiatric substrate could explain some of these differences between the two study subgroups. Further data are needed to complete the acute and long‑term distinctive profiles of COVID‑19‑related mental illness in older and younger patients. AD - Faculty of Medicine and Pharmacy, ‘Dunarea de Jos’ University of Galati, 800216 Galati, Romania Clinical Medical Department, Dermatology, ReForm UDJ, Faculty of Medicine and Pharmacy, ‘Dunărea de Jos’ University of Galati, 800216 Galati, Romania Department 9‑Physical and Rehabilitation Medicine, ‘Carol Davila’ University of Medicine and Pharmacy of Bucharest, 020021 Bucharest, Romania AU - Sârbu,Fabiola AU - Oprea,Violeta,Diana AU - Tatu,Alin,Laurențiu AU - Drima,Eduard,Polea AU - Ștefănescu,Cristina AU - Nechita,Aurel AU - Onose,Gelu AU - Romila,Aurelia DA - 2022/08/01 DO - 10.3892/etm.2022.11424 IS - 2 JO - Exp Ther Med KW - COVID‑19 elderly psychiatric manifestations sleep disorder depression cognitive impairment immuno‑senescence PY - 2022 SN - 1792-0981 1792-1015 SP - 497 ST - COVID‑19‑related psychiatric manifestations requiring hospitalization: Analysis in older vs. younger patients T2 - Experimental and Therapeutic Medicine TI - COVID‑19‑related psychiatric manifestations requiring hospitalization: Analysis in older vs. younger patients UR - https://doi.org/10.3892/etm.2022.11424 VL - 24 ER -