TY - JOUR AB - Histopathological findings are the gold standard for diagnosing lung nodules, and Invasive diagnostic procedures such as percutaneous transthoracic needle biopsy (PTNB) are often inevitable for a confirmative diagnosis. However, the traditional biopsy method is inefficient for the diagnosis of small pulmonary nodules (diameter ≤2.0 cm). The present study aimed to investigate the application of rapid on‑site evaluation (ROSE) in CT‑guided PTNB of pulmonary nodules (≤2.0 cm in diameter). Data from patients undergoing PTNB in the Second Affiliated Hospital of Qiqihar Medical College between June 2018 and June 2021 were retrospectively analyzed. A total of 250 patients were included and divided into the ROSE (n=177) and the non‑ROSE groups (n=73). The comparison of these two groups indicated significantly higher specimen adequacy [93.22% (165/177) vs. 71.23% (52/73)] and diagnostic accuracy [90.40% (160/177) vs. 68.49% (50/73)], as well as a significantly lower rate of secondary biopsies [5.08% (9/177) vs. 28.77% (21/73)], in the ROSE group. The coincidence rate between the diagnosis with ROSE and the final pathological results was 96.73%, indicating high consistency (κ=0.925). The results indicated that the application of ROSE in PTNB of pulmonary nodules with a diameter of ≤2.0 cm can ensure sufficient material sampling, improve the diagnostic accuracy and reduce the secondary biopsy rate, without increasing complications. ROSE can ensure high consistency with the results obtained from the pathological evaluation. AD - Medical Imaging Center, The Second Affiliated Hospital of Qiqihar Medical College, Qiqihar, Heilongjiang 161006, P.R. China Clinical and Research Center of Infectious Diseases, Beijing Ditan Hospital, Capital Medical University, Beijing 100015, P.R. China Department of Pathology, Qiqihar Medical College, Qiqihar, Heilongjiang 161006, P.R. China Department of Computed Tomography, Gannan People's Hospital, Qiqihar, Heilongjiang 162100, P.R. China AU - Wang,Dongxu AU - Zhang,Qing AU - Wang,Yuguang AU - Dou,Wei AU - Ding,Guoxu AU - Wen,Qiuting AU - Han,Ying AU - Du,Youli AU - Li,Bo DA - 2022/11/01 DO - 10.3892/etm.2022.11599 IS - 5 JO - Exp Ther Med KW - pulmonary nodule percutaneous transthoracic needle biopsy rapid on‑site evaluation PY - 2022 SN - 1792-0981 1792-1015 SP - 663 ST - Application of rapid on‑site evaluation in computed tomography‑guided percutaneous transthoracic needle biopsy of pulmonary nodules of ≤2.0 cm in diameter T2 - Experimental and Therapeutic Medicine TI - Application of rapid on‑site evaluation in computed tomography‑guided percutaneous transthoracic needle biopsy of pulmonary nodules of ≤2.0 cm in diameter UR - https://doi.org/10.3892/etm.2022.11599 VL - 24 ER -