TY - JOUR AB - The prognosis of intraductal papillary‑mucinous neoplasm is superior to that of conventional pancreatic ductal adenocarcinoma. Only a few advanced cases of intraductal papillary‑mucinous carcinoma (IPMC) have been reported to date. We herein report the case of a 78‑year‑old male patient with advanced pancreatobiliary type IPMC with portal vein invasion and liver metastasis. The IPMC invaded the portal vein to form a tumor thrombus and it also metastasized to the liver via the portal vein. After receiving best supportive care, the patient succumbed to the disease following an exacerbation of IPMC 90 days after the initial presentation. On autopsy, a very long tumor thrombus was identified, along with liver metastatic lesions, which had retained the structure of the primary IPMC on histological examination. AD - Clinical Study and Training Center, Saiseikai Chuwa Hospital, Sakurai, Nara 633‑0054, Japan Department of Gastroenterology, Saiseikai Chuwa Hospital, Sakurai, Nara 633‑0054, Japan Department of Pathology, Saiseikai Chuwa Hospital, Sakurai, Nara 633‑0054, Japan AU - Matsushita,Naohiro AU - Douhara,Akitoshi AU - Ueno,Hirotsugu AU - Asada,Shohei AU - Murata,Koji AU - Yanase,Koji AU - Tsutsumi,Masahiro DA - 2021/05/01 DO - 10.3892/mco.2021.2263 IS - 5 JO - Mol Clin Oncol KW - intraductal papillary‑mucinous carcinoma portal invasion portal vein tumor thrombosis liver metastasis PY - 2021 SN - 2049-9450 2049-9469 SP - 101 ST - Intraductal papillary‑mucinous carcinoma with portal vein tumor thrombus and multifocal liver metastasis: An autopsy case T2 - Molecular and Clinical Oncology TI - Intraductal papillary‑mucinous carcinoma with portal vein tumor thrombus and multifocal liver metastasis: An autopsy case UR - https://doi.org/10.3892/mco.2021.2263 VL - 14 ER -