TY - JOUR AB - Pilomatrical carcinosarcomas are very rare tumors. To the best of our knowledge, only nine cases diagnosed with pilomatrical carcinosarcomas have been reported. The present study reported on a case of pilomatrical carcinosarcoma in the posterior part of the left auricle of a 100‑year‑old male patient. The tumor histologically comprised the following two components: Pilomatrical carcinoma and undifferentiated spindle cell sarcoma. The pilomatrical carcinoma comprised atypical basaloid cells and shadow cells. The basaloid cells had basophilic cytoplasm, clear nucleoli and deeply stained nuclear chromatin. The undifferentiated spindle cell sarcoma comprised atypical spindle cells. Both components contained numerous mitotic cells. The boundary area between the carcinoma and sarcoma smoothly transitioned into each other. The carcinoma cells and a portion of the sarcoma cells were positive for β‑catenin in the cytoplasm with or without the nuclei. These results suggested that the two components developed from the same origin. AD - Department of Diagnostic Pathology, Toyooka Hospital, Toyooka, Hyogo 668‑8501, Japan Department of Laboratory Medicine, Shizuoka Medical Center, Shimizu‑Cho, Shizuoka 411‑8611, Japan Department of Plastic and Reconstructive Surgery, Toyooka Hospital, Toyooka, Hyogo 668‑8501, Japan Department of Dermatology, Toyooka Hospital, Toyooka, Hyogo 668‑8501, Japan Department of Stem Cell Disorders, Kansai Medical University, Hirakata, Osaka 573‑1010, Japan AU - Suemune,Kazuki AU - Adachi,Yasushi AU - Takagi,Masayuki AU - Tokuriki,Toshiharu AU - Akiyama,Hajime AU - Ikehara,Susumu DA - 2021/12/01 DO - 10.3892/mco.2021.2426 IS - 6 JO - Mol Clin Oncol KW - pilomatrical carcinosarcoma super‑elderly human skin PY - 2021 SN - 2049-9450 2049-9469 SP - 264 ST - Pilomatrical carcinosarcoma in the very elderly: Α case report T2 - Molecular and Clinical Oncology TI - Pilomatrical carcinosarcoma in the very elderly: Α case report UR - https://doi.org/10.3892/mco.2021.2426 VL - 15 ER -