TY - JOUR AB - The drawback of intracorporeal gastrojejunostomy using only endoscopic linear staplers in antecolic Roux‑en‑Y (R‑Y) reconstruction with its efferent loop located on the patient's left side following totally laparoscopic distal gastrectomy (TLDG) is the occurrence of anastomotic failure, even though this reconstruction system is assumed to prevent intraoperative and postoperative twisting of the gastrojejunostomy and lifted jejunum. This case report presents two patients with gastric cancer who underwent intracorporeal gastrojejunostomy consisting of linear stapling and hand suturing in antecolic R‑Y reconstruction with its efferent loop located on the patient's left side following TLDG to prevent anastomotic failure of the gastrojejunostomy. After the sacrificed jejunum was created, linear stapling of the greater curvature of the remnant stomach and the lifted jejunum without dividing the jejunum was performed. After removing the sacrificed jejunum and creating a good view of the posterior side of the stapler entry hole, the stapler entry hole was closed from the posterior side to the anterior side, using a single‑layer full‑thickness and serosubmucosal hand suturing technique with knotted sutures and a knotless barbed suture. No anastomotic failure of the gastrojejunostomy occurred in either patient. Intracorporeal gastrojejunostomy consisting of linear stapling and hand suturing could be an option for gastrojejunostomy in antecolic R‑Y reconstruction with its efferent loop located on the patient's left side following TLDG because it can aid in the prevention of anastomotic failure. AD - Department of Surgery, Tanigawa Memorial Hospital, Osaka 567‑0031, Japan Department of Surgery, Otori Stomach and Intestines Hospital, Osaka 593‑8311, Japan AU - Tokuhara,Takaya AU - Nakata,Eiji AU - Ogata,Akihito AU - Tenjo,Toshiyuki AU - Kawai,Isao AU - Kondo,Keisaku AU - Hatabe,Shigeru AU - Yokoyama,Kazutake DA - 2022/02/01 DO - 10.3892/mco.2021.2480 IS - 2 JO - Mol Clin Oncol KW - totally laparoscopic distal gastrectomy Roux‑en‑Y reconstruction intracorporeal gastrojejunostomy anastomotic failure PY - 2022 SN - 2049-9450 2049-9469 SP - 47 ST - Intracorporeal gastrojejunostomy in Roux‑en‑Y reconstruction with its efferent loop located on the patient's left side following totally laparoscopic distal gastrectomy: A case report T2 - Molecular and Clinical Oncology TI - Intracorporeal gastrojejunostomy in Roux‑en‑Y reconstruction with its efferent loop located on the patient's left side following totally laparoscopic distal gastrectomy: A case report UR - https://doi.org/10.3892/mco.2021.2480 VL - 16 ER -