TY - JOUR AB - In the present study, the incidence of surgical wound complications in patients with large and deep high‑grade soft tissue sarcoma (STS) was investigated. In addition, the disease‑specific and event‑free survival rates were examined in these patients. In total, 30 adult patients with primary high‑grade deep STS with a size of 10 cm or greater were treated in the current study. Of the 30 patients, 16 (53%) developed a total of 19 wound complications. In addition, 10 cases of wound dehiscence, 5 cases of infections, 3 cases of hematomas and 1 case of lymphorrhea were reported, while 3 patients with postoperative infections underwent additional surgical treatment. Longer surgery duration was associated with wound complications (P=0.04). The disease‑specific survival was 58.5% at 3 years and 46.1% at 5 years after treatment. Furthermore, local recurrence was detected in 13 patients and distant metastasis was identified in 17 patients as the first relapse. The 3‑ and 5‑year event‑free survival rates were 24.4 and 16.3%, respectively. In conclusion, patients with large and high‑grade, deep STSs presented a high complication rate; therefore, careful wound care is required in these patients. Furthermore, it should be also taken into account that these patients have a greater risk of tumor‑associated events and mortality. AD - Department of Orthopaedic Surgery, Mie University Hospital, Tsu, Mie 514‑8507, Japan AU - Nakamura,Tomoki AU - Matsumine,Akihiko AU - Matsubara,Takao AU - Asanuma,Kunihiro AU - Uchida,Astumasa AU - Sudo,Akihiro DA - 2015/08/01 DO - 10.3892/ol.2015.3289 EP - 844 IS - 2 JO - Oncol Lett KW - soft tissue sarcoma wound complication survival PY - 2015 SN - 1792-1074 1792-1082 SP - 841 ST - Clinical characteristics of patients with large and deep soft tissue sarcomas T2 - Oncology Letters TI - Clinical characteristics of patients with large and deep soft tissue sarcomas UR - https://doi.org/10.3892/ol.2015.3289 VL - 10 ER -