TY - JOUR AB - Dose distribution was calculated and analyzed on the basis of 16‑bit computed tomography (CT) images in order to investigate the effect of scanning conditions on CT for metal implants. Stainless steel and titanium rods were inserted into a phantom, and CT images were obtained by scanning the phantom under various scanning conditions: i) Fixed tube current of 230 mA and tube voltages of 100, 120, and 140 kV; and ii) fixed tube voltage of 120 kV and tube currents of 180, 230, and 280 mA. The CT value of the metal rod was exami­ned and corrected. In a Varian treatment planning system, a treatment plan was designed on the basis of the CT images obtained under the set scanning conditions. The dose distributions in the phantom were then calculated and compared. The CT value of the metal area slightly changed upon tube current alteration. The dose distribution in the phantom was also similar. The maximum CT values of the stainless steel rod were 14,568, 14,127 and 13,295 HU when the tube voltages were modified to 100, 120, and 140 kV, respectively. The corresponding CT values of the titanium rod were 9,420, 8,140 and 7,310 HU. The dose distribution of the radiotherapy plan changed significantly as the tube voltage varied. Compared with the reference dose, the respective maximum dose differences of the stainless steel and titanium rods in the phantom were 5.70, and 6.62% when the tube voltage varied. The changes in tube currents resulted in a maximum dose error of <1% for stainless steel and titanium. In CT imaging, changes in tube voltages can significantly alter the CT values of metal implants. Thus, this can lead to large errors in radiotherapy dose distributions. AD - Radiotherapy Department, Second People's Hospital of Changzhou, Nanjing Medical University, Changzhou 213003, P.R. China Radiotherapy Department, Changzhou Cancer Hospital of Soochow University, Changzhou 213001, P.R. China AU - Gao,Liugang AU - Sun,Hongfei AU - Ni,Xinye AU - Fang,Mingming AU - Lin,Tao DA - 2018/02/01 DO - 10.3892/ol.2017.7586 EP - 2379 IS - 2 JO - Oncol Lett KW - scanning condition metal 16‑bit dose distribution CT radiotherapy PY - 2018 SN - 1792-1074 1792-1082 SP - 2373 ST - Effects of 16-bit CT imaging scanning conditions for metal implants on radiotherapy dose distribution T2 - Oncology Letters TI - Effects of 16-bit CT imaging scanning conditions for metal implants on radiotherapy dose distribution UR - https://doi.org/10.3892/ol.2017.7586 VL - 15 ER -