TY - JOUR AB - Acetylsalicylic acid, also known as aspirin, is often used in clinical antipyretic, analgesic and antiplatelet therapy. Aspirin can cause numerous side effects in the gastrointestinal (GI) tract, ranging from unpleasant GI symptoms without gastric mucosal lesions to ulcer bleeding and even death. However, recent studies have found that aspirin can significantly prevent GI tumors. Despite impressive advances in cancer research, screening and treatment options, GI tumors remain a leading cause of death worldwide. Prevention is a far better option than treatment for tumors. Therefore, the present review assesses the pros and cons of aspirin on the GI tract and, on this the basis, the appropriate dose of aspirin to protect it. AD - Department of Internal Medicine, The Medical School of Ningbo University, Ningbo, Zhejiang 315000, P.R. China Department of Gastroenterology, Ningbo First Hospital, Ningbo, Zhejiang 315000, P.R. China AU - Li,Zhuoya AU - Wang,Zheng AU - Shen,Baile AU - Chen,Chen AU - Ding,Xiaoyun AU - Song,Haojun DA - 2020/09/01 DO - 10.3892/ol.2020.11817 EP - 2578 IS - 3 JO - Oncol Lett KW - aspirin effect gastrointestinal cancer gastrointestinal side effects gastrointestinal benefit PY - 2020 SN - 1792-1074 1792-1082 SP - 2567 ST - Effects of aspirin on the gastrointestinal tract: Pros vs. cons (Review) T2 - Oncology Letters TI - Effects of aspirin on the gastrointestinal tract: Pros vs. cons (Review) UR - https://doi.org/10.3892/ol.2020.11817 VL - 20 ER -