TY - JOUR AB - Liposarcoma is a rare malignant tumor type and surgical resection is the gold standard treatment. The present study reported on the case of a 51‑year‑old woman who presented with a mass in the left upper abdomen. Computed tomography revealed a 32‑cm giant retroperitoneal liposarcoma. Complete tumor resection was performed without the removal of other organs. Postoperative pathological examination indicated retroperitoneal well‑differentiated liposarcoma and immunohistochemistry revealed S‑100(‑), MDM2(+), vimentin(+), CDK4(+), p16(+) and STAT6(+) results. The patient recovered well after the surgery. Complete tumor resection during the first surgery is key to cure liposarcoma. The present case report will be helpful for clinical oncologists to fully understand giant retroperitoneal liposarcoma and treat it accordingly. AD - Department of Urology, Hexi University Affiliated Zhangye People's Hospital, Zhangye, Gansu 734000, P.R. China Department of Endoscopy Center, Hexi University Affiliated Zhangye People's Hospital, Zhangye, Gansu 734000, P.R. China Department of Urology, First Affiliated Hospital, School of Medicine, Shihezi University, Shihezi, Xinjiang 830000, P.R. China Institute of Urology, Hexi University, Zhangye, Gansu 734000, P.R. China Department of Urology, Hexi University Affiliated Zhangye People's Hospital, Zhangye, Gansu 734000, P.R. China AU - Wei,Xiaoyi AU - Qin,Yujie AU - Ouyang,Song AU - Qian,Jun AU - Tu,Song AU - Yao,Jiaxi DA - 2022/09/01 DO - 10.3892/ol.2022.13434 IS - 3 JO - Oncol Lett KW - liposarcoma case report surgery PY - 2022 SN - 1792-1074 1792-1082 SP - 314 ST - Challenging surgical treatment of giant retroperitoneal liposarcoma: A case report T2 - Oncology Letters TI - Challenging surgical treatment of giant retroperitoneal liposarcoma: A case report UR - https://doi.org/10.3892/ol.2022.13434 VL - 24 ER -