TY - JOUR AB - Malignant Triton tumour represents an extremely rare mesenchymal malignancy exhibiting histopathologic patterns of peripheral nerve sheath tumours and rhabdomyoblastic components, the latter usually determining the mostly fatal outcome. We report on a 26-year old patient diagnosed with malignant Triton tumour who developed multiple recurrences despite repeated aggressive surgery, chemo- and radiotherapy during an 8-year period. After Northern blotting analysis of an excised in-transit metastasis had revealed expression of retinoic receptors α and γ, the patient received experimental treatment with isotretinoin and interferon-α for one year and remains without any evidence of disease for more than three years. This is the first report on a long-term survivor of multiple recurrences of malignant Triton tumour. AD - Clinical Division of Oncology, Department of Medicine I, University Hospital of Vienna, A-1090 Vienna, Austria. wolfgang.koestler@akh-wien.ac.at null AU - Köstler,Wolfgang,J. AU - Amann,Gabriele AU - Grunt,Thomas,W. AU - Singer,Christian,F. AU - Schneider,Sonja,M. AU - Brodowicz,Thomas AU - Tomek,Sandra AU - Zielinski,Christoph,C. DA - 2003/05/01 DO - 10.3892/or.10.3.533 EP - 535 IS - 3 JO - Oncol Rep PY - 2003 SN - 1021-335X 1791-2431 SP - 533 ST - Recurrent malignant Triton tumour: First report on a long time survivor T2 - Oncology Reports TI - Recurrent malignant Triton tumour: First report on a long time survivor UR - https://doi.org/10.3892/or.10.3.533 VL - 10 ER -