TY - JOUR AB - A patient with a known history of resected pheochromocytoma was evaluated for recurrent paroxysmal hypertension. The recurrent tumor was localized by magnetic resonance imaging and by somatostatin receptor scintigraphy. Since this scintigraphy demonstrated the presence of somatostatin receptors, empiric treatment with the somatostatin analogue octreotide was initiated in an attempt to stabilize catecholamine secretion prior to attempted surgical resection. The patient experienced a paradoxical reaction manifested by an acute hypertensive crisis which was rapidly responsive to intravenous nicardipine. Stimulation of such a hypertensive crisis by octreotide has not previously been reported. The etiology of this reaction is unclear. We conclude that octreotide and other somatostatin analogues should be administered with extreme caution to patients with known or suspected pheochromocytomas. AD - MEM SLOAN KETTERING CANC CTR,DEPT ANESTHESIOL & CRIT CARE MED,CRIT CARE SERV,NEW YORK,NY 10021. AU - SALTZ,LB AU - TIERSTEN,A AU - HASSAN,BN AU - GROEGER,JS DA - 1995/11/01 DO - 10.3892/or.2.6.1129 EP - 1130 IS - 6 JO - Oncol Rep PY - 1995 SN - 1021-335X 1791-2431 SP - 1129 ST - ACUTE HYPERTENSIVE CRISIS FOLLOWING OCTREOTIDE ADMINISTRATION IN A PATIENT WITH MALIGNANT PHEOCHROMOCYTOMA T2 - Oncology Reports TI - ACUTE HYPERTENSIVE CRISIS FOLLOWING OCTREOTIDE ADMINISTRATION IN A PATIENT WITH MALIGNANT PHEOCHROMOCYTOMA UR - https://doi.org/10.3892/or.2.6.1129 VL - 2 ER -