TY - JOUR AB - The objective of this study was to characterize and differentiate vascular patterns of choroidal melanomas and choroidal metastases by color flow mapping (CFM). We conducted a retrospective chart study on CFM findings in 18 patients with choroidal melanomas and 10 patients with choroidal metastases. We evaluated the possibilities of applying CFM to identify hypo- versus hyper-vascularity within the tumor, a central ‘dominant vessel’, and Doppler signals in the tumor's center and/or periphery. CFM demonstrated hypervascular patterns in 33% melanomas and 100% metastases (p<0.0001). CFM identified a central dominant vessel in 94% melanomas and 0/10 metastases (p<0.0001). Vascularity occupied the center of 11/18 melanomas and 0/10 metastases (p<0.0001), the periphery of 2/18 melanomas and 9/10 metastases (p<0.0001), and equally occupied the tumor's center and periphery of 5/18 melanomas and 1/10 metastases (p<0.0001). Based on our findings, we conclude that CFM was capable of non-invasively demonstrating different and distinct vascular patterns in malignant choroidal melanomas and choroidal metastases. AD - Department of Ophthalmology, Tel-Aviv Medical Center, Tel-Aviv 64239, Israel. meiraneu@netvision.net.il null AU - Neudorfer,Meira AU - Waisbourd,Michael AU - Anteby,Irene AU - Liran,Alon AU - Goldenberg,Dafna AU - Barak,Adiel AU - Kessler,Ada DA - 2011/01/01 DO - 10.3892/or_00001046 EP - 96 IS - 1 JO - Oncol Rep PY - 2011 SN - 1021-335X 1791-2431 SP - 91 ST - Color flow mapping: a non-invasive tool for characterizing and differentiating between uveal melanomas and choroidal metastases T2 - Oncology Reports TI - Color flow mapping: a non-invasive tool for characterizing and differentiating between uveal melanomas and choroidal metastases UR - https://doi.org/10.3892/or_00001046 VL - 25 ER -