1
|
Stone HB, Coleman CN, Anscher MS and
McBride WH: Effects of radiation on normal tissue: Consequences and
mechanisms. Lancet Oncol. 4:529–536. 2003. View Article : Google Scholar : PubMed/NCBI
|
2
|
Cappuccini F, Eldh T, Bruder D, Gereke M,
Jastrow H, SchulzeOsthoff K, Fischer U, Köhler D, Stuschke M and
Jendrossek V: New insights into the molecular pathology of
radiation-induced pneumopathy. Radiother Oncol. 101:86–92. 2011.
View Article : Google Scholar : PubMed/NCBI
|
3
|
Trott KR, Herrmann T and Kasper M: Target
cells in raditation pneumopathy. Int J Radiat Oncol Biol Phys.
58:463–469. 2004. View Article : Google Scholar : PubMed/NCBI
|
4
|
Kim KK, Kugler MC, Wolters PJ, Robillard
L, Galvez MG, Brumwell AN, Sheppard D and Chapman HA: Alveolar
epithelial cell mesenchymal transition develops in vivo during
pulmonary fibrosis and is regulated by the extracellular matrix.
Proc Natl Acad Sci USA. 103:13180–13185. 2006. View Article : Google Scholar : PubMed/NCBI
|
5
|
Willis BC, Liebler JM, LubyPhelps K,
Nicholson AG, Crandall ED, du Bois RM and Borok Z: Induction of
epithelial-mesenchymal transition in alveolar epithelial cells by
transforming growth factor-β1: Potential role in idiopathic
pulmonary fibrosis. Am J Pathol. 166:1321–1332. 2005. View Article : Google Scholar : PubMed/NCBI
|
6
|
Kalluri R and Weinberg RA: The basics of
epithelial-mesenchymal transition. J Clin Invest. 119:1420–1428.
2009. View
Article : Google Scholar : PubMed/NCBI
|
7
|
Almeida C, Nagarajan D, Tian J, Leal SW,
Wheeler K, Munley M, Blackstock W and Zhao W: The role of alveolar
epithelium in radiation-induced lung injury. PLoS One.
8:e536282013. View Article : Google Scholar : PubMed/NCBI
|
8
|
Williams JP, Brown SL, Georges GE,
HauerJensen M, Hill RP, Huser AK, Kirsch DG, Macvittie TJ, Mason
KA, Medhora MM, et al: Animal models for medical countermeasures to
radiation exposure. Radiat Res. 173:557–578. 2010. View Article : Google Scholar : PubMed/NCBI
|
9
|
Hopewell JW, Rezvani M and Moustafa HF:
The pig as a model for the study of radiation effects on the lung.
Int J Radiat Biol. 76:447–452. 2000. View Article : Google Scholar : PubMed/NCBI
|
10
|
Li M, Abdollahi A, Gröne HJ, Lipson KE,
Belka C and Huber PE: Late treatment with imatinib mesylate
ameliorates radiation-induced lung fibrosis in a mouse model.
Radiat Oncol. 4:662009. View Article : Google Scholar : PubMed/NCBI
|
11
|
Molthen RC, Wu Q, Fish BL, Moulder JE,
Jacobs ER and Medhora MM: Mitigation of radiation induced pulmonary
vascular injury by delayed treatment with captopril. Respirology.
17:1261–1268. 2012. View Article : Google Scholar : PubMed/NCBI
|
12
|
Travis EL: The sequence of histological
changes in mouse lungs after single doses of x-rays. Int J Radiat
Oncol Biol Phys. 6:345–347. 1980. View Article : Google Scholar : PubMed/NCBI
|
13
|
Uhal BD: Cell cycle kinetics in the
alveolar epithelium. Am J Physiol. 272:L1030–L1045. 1997.
|
14
|
Alcorn JF and Wright JR: Surfactant
protein A inhibits alveolar macrophage cytokine production by
CD14-independent pathway. Am J Physiol Lung Cell Mol Physiol.
286:L129–L136. 2004. View Article : Google Scholar : PubMed/NCBI
|
15
|
Vazquez de Lara LG, Umstead TM, Davis SE
and Phelps DS: Surfactant protein A increases matrix
metalloproteinase-9 production by THP-1 cells. Am J Physiol Lung
Cell Mol Physiol. 285:L899–L906. 2003. View Article : Google Scholar : PubMed/NCBI
|
16
|
Hallman M, Maasilta P, Kivisaari L and
Mattson K: Changes in surfactant in bronchoalveolar lavage fluid
after hemithorax irradiation in patients with mesothelioma. Am Rev
Respir Dis. 141:998–1005. 1990. View Article : Google Scholar : PubMed/NCBI
|
17
|
Sasaki R, Soejima T, Matsumoto A, Maruta
T, Yamada K, Ota Y, Kawabe T, Nishimura H, Sakai E, Ejima Y, et al:
Clinical significance of serum pulmonary surfactant proteins A and
D for the early detection of radiation pneumonitis. Int J Radiat
Oncol Biol Phys. 50:301–307. 2001. View Article : Google Scholar : PubMed/NCBI
|
18
|
Wynn TA: Cellular and molecular mechanisms
of fibrosis. J Pathol. 214:199–210. 2008. View Article : Google Scholar : PubMed/NCBI
|
19
|
Wynn TA: Integrating mechanisms of
pulmonary fibrosis. J Exp Med. 208:1339–1350. 2011. View Article : Google Scholar : PubMed/NCBI
|
20
|
Nagarajan D, Melo T, Deng Z, Almeida C and
Zhao W: ERK/GSK3β/Snail signaling mediates radiation-induced
alveolar epithelial-to-mesenchymal transition. Free Radic Biol Med.
52:983–992. 2012. View Article : Google Scholar : PubMed/NCBI
|
21
|
Verrecchia F and Mauviel A: Transforming
growth factor-beta and fibrosis. World J Gastroenterol.
13:3056–3062. 2007.PubMed/NCBI
|
22
|
Thannickal VJ, Toews GB, White ES, Lynch
JP III and Martinez FJ: Mechanisms of pulmonary fibrosis. Annu Rev
Med. 55:395–417. 2004. View Article : Google Scholar : PubMed/NCBI
|
23
|
Zhao L, Sheldon K, Chen M, Yin MS, Hayman
JA, Kalemkerian GP, Arenberg D, Lyons SE, Curtis JL, Davis M, et
al: The predictive role of plasma TGF-β1 during radiation therapy
for radiation-induced lung toxicity deserves further study in
patients with non-small cell lung cancer. Lung Cancer. 59:232–239.
2008. View Article : Google Scholar : PubMed/NCBI
|
24
|
Visse R and Nagase H: Matrix
metalloproteinases and tissue inhibitors of metalloproteinases:
Structure, function, and biochemistry. Circ Res. 92:827–839. 2003.
View Article : Google Scholar : PubMed/NCBI
|
25
|
Atkinson JJ and Senior RM: Matrix
metalloproteinase-9 in lung remodeling. Am J Respir Cell Mol Biol.
28:12–24. 2003. View Article : Google Scholar : PubMed/NCBI
|
26
|
López-Novoa JM and Nieto MA: Inflammation
and EMT: An alliance towards organ fibrosis and cancer progression.
EMBO Mol Med. 1:303–314. 2009. View Article : Google Scholar : PubMed/NCBI
|
27
|
Tan TK, Zheng G, Hsu TT, Wang Y, Lee VW,
Tian X, Wang Y, Cao Q, Wang Y and Harris DC: Macrophage matrix
metalloproteinase-9 mediates epithelial-mesenchymal transition in
vitro in murine renal tubular cells. Am J Pathol. 176:1256–1270.
2010. View Article : Google Scholar : PubMed/NCBI
|
28
|
Cheng S and Lovett DH: Gelatinase A
(MMP-2) is necessary and sufficient for renal tubular cell
epithelial-mesenchymal transformation. Am J Pathol. 162:1937–1949.
2003. View Article : Google Scholar : PubMed/NCBI
|
29
|
Lee WH, Warrington JP, Sonntag WE and Lee
YW: Irradiation alters MMP-2/TIMP-2 system and collagen type IV
degradation in brain. Int J Radiat Oncol Biol Phys. 82:1559–1566.
2012. View Article : Google Scholar : PubMed/NCBI
|
30
|
StrupPerrot C, Vozenin-Brotons M-C,
Vandamme M, Linard C and Mathé D: Expression of matrix
metalloproteinases and tissue inhibitor metalloproteinases
increases in X-irradiated rat ileum despite the disappearance of
CD8a T cells. World J Gastroenterol. 11:6312–6321. 2005.PubMed/NCBI
|
31
|
Yang K, Palm J, König J, Seeland U,
Rosenkranz S, Feiden W, Rübe C and Rübe CE:
Matrix-Metallo-Proteinases and their tissue inhibitors in
radiation-induced lung injury. Int J Radiat Biol. 83:665–676. 2007.
View Article : Google Scholar : PubMed/NCBI
|
32
|
Susskind H, Hymowitz MH, Lau YH, Atkins
HL, Hurewitz AN, Valentine ES, Meek AG and Zucker S: Increased
plasma levels of matrix metalloproteinase-9 and tissue inhibitor of
metalloproteinase-1 in lung and breast cancer are altered during
chest radiotherapy. Int J Radiat Oncol Biol Phys. 56:1161–1169.
2003. View Article : Google Scholar : PubMed/NCBI
|
33
|
Daley WP, Peters SB and Larsen M:
Extracellular matrix dynamics in development and regenerative
medicine. J Cell Sci. 121:255–264. 2008. View Article : Google Scholar : PubMed/NCBI
|
34
|
Shintani Y, Maeda M, Chaika N, Johnson KR
and Wheelock MJ: Collagen I promotes epithelial-to-mesenchymal
transition in lung cancer cells via transforming growth factor-β
signaling. Am J Respir Cell Mol Biol. 38:95–104. 2008. View Article : Google Scholar : PubMed/NCBI
|
35
|
Zeisberg M, Bonner G, Maeshima Y, et al:
Renal fibrosis: Collagen composition and assembly regulates
epithelial-mesenchymal transdifferentiation. Am J Pathol.
159:1313–1321. 2001. View Article : Google Scholar : PubMed/NCBI
|
36
|
Buckley ST, Medina C, Davies AM and
Ehrhardt C: Cytoskeletal re-arrangement in TGF-β1-induced alveolar
epithelial-mesenchymal transition studied by atomic force
microscopy and high-content analysis. Nanomedicine (Lond).
8:355–364. 2012.
|
37
|
Kolb M, Margetts PJ, Sime PJ and Gauldie
J: Proteoglycans decorin and biglycan differentially modulate
TGF-beta-mediated fibrotic responses in the lung. Am J Physiol Lung
Cell Mol Physiol. 280:L1327–L1334. 2001.PubMed/NCBI
|
38
|
Kasai H, Allen JT, Mason RM, Kamimura T
and Zhang Z: TGF-β1 induces human alveolar epithelial to
mesenchymal cell transition (EMT). Respir Res. 6:562005. View Article : Google Scholar : PubMed/NCBI
|