Open Access

Trichomegaly and scalp hair changes following treatment with erlotinib in pulmonary adenocarcinoma patients: A case report and literature review

  • Authors:
    • Hua Zheng
    • Hongmei Zhang
    • Tongmei Zhang
    • Qunhui Wang
    • Fanbin Hu
    • Baolan Li
  • View Affiliations

  • Published online on: June 16, 2016     https://doi.org/10.3892/etm.2016.3460
  • Pages: 1287-1292
  • Copyright: © Zheng et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Erlotinib is among the oral EGFR-tyrosine kinase inhibitors used to treat non-small cell lung cancer. The common side effects of erlotinib include acne form rash and diarrhea. Eyelash trichomegaly and alterations of scalp hair are rarely observed symptoms. In the present study, we report changes in eyelash trichomegaly and scalp hair in six cases of pulmonary adenocarcinoma patients that had been administered erlotinib. The symptoms of eyelash trichomegaly include curly, irregular, excessively long and brittle eyelashes, and alterations of scalp hair include curly or straight, brittle, fine or rigid, reduced growth rate and volume. Since these side effects does not substantially impact patient quality of life, no treatments were administered. These changes in eyelashes and scalp hair gradually disappeared after withdrawal of erlotinib.
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September-2016
Volume 12 Issue 3

Print ISSN: 1792-0981
Online ISSN:1792-1015

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Spandidos Publications style
Zheng H, Zhang H, Zhang T, Wang Q, Hu F and Li B: Trichomegaly and scalp hair changes following treatment with erlotinib in pulmonary adenocarcinoma patients: A case report and literature review. Exp Ther Med 12: 1287-1292, 2016
APA
Zheng, H., Zhang, H., Zhang, T., Wang, Q., Hu, F., & Li, B. (2016). Trichomegaly and scalp hair changes following treatment with erlotinib in pulmonary adenocarcinoma patients: A case report and literature review. Experimental and Therapeutic Medicine, 12, 1287-1292. https://doi.org/10.3892/etm.2016.3460
MLA
Zheng, H., Zhang, H., Zhang, T., Wang, Q., Hu, F., Li, B."Trichomegaly and scalp hair changes following treatment with erlotinib in pulmonary adenocarcinoma patients: A case report and literature review". Experimental and Therapeutic Medicine 12.3 (2016): 1287-1292.
Chicago
Zheng, H., Zhang, H., Zhang, T., Wang, Q., Hu, F., Li, B."Trichomegaly and scalp hair changes following treatment with erlotinib in pulmonary adenocarcinoma patients: A case report and literature review". Experimental and Therapeutic Medicine 12, no. 3 (2016): 1287-1292. https://doi.org/10.3892/etm.2016.3460