Rotavirus‑associated immune thrombocytopenic purpura in children: A retrospective study

  • Authors:
    • Qi Ai
    • Jing Yin
    • Sen Chen
    • Lijin Qiao
    • Na Luo
  • View Affiliations

  • Published online on: August 9, 2016     https://doi.org/10.3892/etm.2016.3582
  • Pages: 2187-2190
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Abstract

Certain studies have previously indicated that an association may exist between rotavirus infection and primary immune thrombocytopenic purpura (ITP). The present retrospective study aimed to investigate whether rotavirus may cause ITP in children. Firstly, the incidence of ITP in children with or without rotavirus diarrhea was compared. A 14.58% incident rate was observed in children with rotavirus diarrhea compared with a 7.22% incident rate in children without rotavirus diarrhea. Subsequently, the clinical features of ITP children with or without rotavirus infection were compared. The results indicated that ITP children with rotavirus infection were significantly younger, showed significantly decreased mean platelet volume (MPV) levels and presented a significantly higher frequency of bleeding score of 3 against ITP children without rotavirus infection. In conclusion, these findings suggest that rotavirus serves a causative role in ITP.
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October-2016
Volume 12 Issue 4

Print ISSN: 1792-0981
Online ISSN:1792-1015

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Spandidos Publications style
Ai Q, Yin J, Chen S, Qiao L and Luo N: Rotavirus‑associated immune thrombocytopenic purpura in children: A retrospective study. Exp Ther Med 12: 2187-2190, 2016
APA
Ai, Q., Yin, J., Chen, S., Qiao, L., & Luo, N. (2016). Rotavirus‑associated immune thrombocytopenic purpura in children: A retrospective study. Experimental and Therapeutic Medicine, 12, 2187-2190. https://doi.org/10.3892/etm.2016.3582
MLA
Ai, Q., Yin, J., Chen, S., Qiao, L., Luo, N."Rotavirus‑associated immune thrombocytopenic purpura in children: A retrospective study". Experimental and Therapeutic Medicine 12.4 (2016): 2187-2190.
Chicago
Ai, Q., Yin, J., Chen, S., Qiao, L., Luo, N."Rotavirus‑associated immune thrombocytopenic purpura in children: A retrospective study". Experimental and Therapeutic Medicine 12, no. 4 (2016): 2187-2190. https://doi.org/10.3892/etm.2016.3582