Influencing factors of transient elastography in detecting liver stiffness

Corrigendum in: /10.3892/etm.2018.6864

  • Authors:
    • Rong Shan
    • Hong Yin
    • Wenjuan Yang
    • Jianzhi Li
    • Meifang Zhang
    • Min Zhao
    • Jiang Shao
    • Aiguang Wang
  • View Affiliations

  • Published online on: August 24, 2016     https://doi.org/10.3892/etm.2016.3617
  • Pages: 2302-2306
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Abstract

Liver stiffness, which correlates well with liver fibrosis stage, can be measured noninvasively by transient elastography, also known as Fibroscan. The present study aimed to determine the independent factors influencing Fibroscan detection by multiple regression analysis. A total of 181 patients who required liver biopsy were enrolled. Liver stiffness measurement (LSM) was detected by Fibroscan on the day of liver biopsy, while clinical information and routine biochemical examination results were also collected. Correlation was analyzed by Spearman's correlation, and multiple regression analysis was performed to analyze the independent influencing factors. The results demonstrated that platelet (PLT) levels, serum albumin (ALB), prothrombin activity (PTA) and body mass index (BMI) were independent predictors of liver stiffness. The contribution of these four predictors to the regression equation was in the following descending order: PLT (negative correlation) > ALB (negative correlation) > PTA (negative correlation) > BMI (positive correlation). In conclusion, the parameters of PLT, ALB, PTA and BMI are independent predicting factors affecting Fibroscan detection. Therefore, the diagnosis and evaluation of liver fibrosis should comprehensively consider the results of Fibroscan, and clinical and laboratory examinations.
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October-2016
Volume 12 Issue 4

Print ISSN: 1792-0981
Online ISSN:1792-1015

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Spandidos Publications style
Shan R, Yin H, Yang W, Li J, Zhang M, Zhao M, Shao J and Wang A: Influencing factors of transient elastography in detecting liver stiffness Corrigendum in /10.3892/etm.2018.6864 . Exp Ther Med 12: 2302-2306, 2016
APA
Shan, R., Yin, H., Yang, W., Li, J., Zhang, M., Zhao, M. ... Wang, A. (2016). Influencing factors of transient elastography in detecting liver stiffness Corrigendum in /10.3892/etm.2018.6864 . Experimental and Therapeutic Medicine, 12, 2302-2306. https://doi.org/10.3892/etm.2016.3617
MLA
Shan, R., Yin, H., Yang, W., Li, J., Zhang, M., Zhao, M., Shao, J., Wang, A."Influencing factors of transient elastography in detecting liver stiffness Corrigendum in /10.3892/etm.2018.6864 ". Experimental and Therapeutic Medicine 12.4 (2016): 2302-2306.
Chicago
Shan, R., Yin, H., Yang, W., Li, J., Zhang, M., Zhao, M., Shao, J., Wang, A."Influencing factors of transient elastography in detecting liver stiffness Corrigendum in /10.3892/etm.2018.6864 ". Experimental and Therapeutic Medicine 12, no. 4 (2016): 2302-2306. https://doi.org/10.3892/etm.2016.3617