Open Access

Relevance of clinical features in the prognosis of bronchopulmonary dysplasia in premature infants

  • Authors:
    • Zhifang Du
    • Xiangyong Kong
    • Yanli Ren
    • Zhichun Feng
    • Junjin Huang
    • Jia Chen
    • Ruijuan Wang
  • View Affiliations

  • Published online on: August 22, 2017     https://doi.org/10.3892/etm.2017.4985
  • Pages: 3433-3440
  • Copyright: © Du et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

The aim of this study is to determine the accuracy rate of bronchopulmonary dysplasia (BPD) diagnosis and risk factors of short‑term poor prognosis for premature infants. This study analyzed the clinical data of 81 premature infants (<32 weeks gestational age) with BPD, who were on oxygen therapy >28 days, and survived >36 weeks (corrected age). Outcome measures included treatments, conditions on the 28th day after birth, oxygen therapy conditions at the 36th week, occurrence of any serious complications during hospital stay. The major risk factors affecting prognosis were ventilation duration, duration of oxygen therapy, application of steroids, hypothyroidism and severity of BPD (all P<0.05). Interventions for complications (n=53) resulted in ceased inhalation of oxygen in 12 infants, improvement of symptoms in 26 infants, and were ineffective in 15 infants. BPD prognosis can be improved by shortening the duration of invasive ventilation and correcting thyroid function.

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October-2017
Volume 14 Issue 4

Print ISSN: 1792-0981
Online ISSN:1792-1015

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Copy and paste a formatted citation
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Spandidos Publications style
Du Z, Kong X, Ren Y, Feng Z, Huang J, Chen J and Wang R: Relevance of clinical features in the prognosis of bronchopulmonary dysplasia in premature infants. Exp Ther Med 14: 3433-3440, 2017
APA
Du, Z., Kong, X., Ren, Y., Feng, Z., Huang, J., Chen, J., & Wang, R. (2017). Relevance of clinical features in the prognosis of bronchopulmonary dysplasia in premature infants. Experimental and Therapeutic Medicine, 14, 3433-3440. https://doi.org/10.3892/etm.2017.4985
MLA
Du, Z., Kong, X., Ren, Y., Feng, Z., Huang, J., Chen, J., Wang, R."Relevance of clinical features in the prognosis of bronchopulmonary dysplasia in premature infants". Experimental and Therapeutic Medicine 14.4 (2017): 3433-3440.
Chicago
Du, Z., Kong, X., Ren, Y., Feng, Z., Huang, J., Chen, J., Wang, R."Relevance of clinical features in the prognosis of bronchopulmonary dysplasia in premature infants". Experimental and Therapeutic Medicine 14, no. 4 (2017): 3433-3440. https://doi.org/10.3892/etm.2017.4985