Open Access

Recurrent primary hyperoxaluria type 2 leads to early post‑transplant renal function loss: A case report

  • Authors:
    • Si Liu
    • Baoshan Gao
    • Gang Wang
    • Weigang Wang
    • Xin Lian
    • Shan Wu
    • Jinyu Yu
    • Yaowen Fu
    • Honglan Zhou
  • View Affiliations

  • Published online on: February 7, 2018     https://doi.org/10.3892/etm.2018.5841
  • Pages: 3169-3172
  • Copyright: © Liu et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Primary hyperoxaluria type 2 is a rare autosomal recessive disorder caused by glyoxylate reductase/hydroxypyruvate reductase deficiency and characterized by recurrent episodes of nephrolithiasis and nephrocalcinosis. Herein, we describe a case of primary hyperoxaluria type 2 in a 33‑year‑old man who failed to respond to conventional therapies; thus renal transplantation was performed. This case demonstrated that, although primary hyperoxaluria type 2 is rare, hyperoxaluria should be suspected and blood oxalate and stone component be examined in patients with recurrent episodes of nephrolithiasis, particularly in those who are unresponsive to conventional therapies. Combined liver‑kidney transplant may be required as kidney transplant alone is not likely to be successful.
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April-2018
Volume 15 Issue 4

Print ISSN: 1792-0981
Online ISSN:1792-1015

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Spandidos Publications style
Liu S, Gao B, Wang G, Wang W, Lian X, Wu S, Yu J, Fu Y and Zhou H: Recurrent primary hyperoxaluria type 2 leads to early post‑transplant renal function loss: A case report. Exp Ther Med 15: 3169-3172, 2018
APA
Liu, S., Gao, B., Wang, G., Wang, W., Lian, X., Wu, S. ... Zhou, H. (2018). Recurrent primary hyperoxaluria type 2 leads to early post‑transplant renal function loss: A case report. Experimental and Therapeutic Medicine, 15, 3169-3172. https://doi.org/10.3892/etm.2018.5841
MLA
Liu, S., Gao, B., Wang, G., Wang, W., Lian, X., Wu, S., Yu, J., Fu, Y., Zhou, H."Recurrent primary hyperoxaluria type 2 leads to early post‑transplant renal function loss: A case report". Experimental and Therapeutic Medicine 15.4 (2018): 3169-3172.
Chicago
Liu, S., Gao, B., Wang, G., Wang, W., Lian, X., Wu, S., Yu, J., Fu, Y., Zhou, H."Recurrent primary hyperoxaluria type 2 leads to early post‑transplant renal function loss: A case report". Experimental and Therapeutic Medicine 15, no. 4 (2018): 3169-3172. https://doi.org/10.3892/etm.2018.5841