Open Access

Randomized clinical trial of physiological ischemic training for patients with coronary heart disease complicated with heart failure: Safety of training, VEGF of peripheral blood and quality of life

  • Authors:
    • Min Gao
    • Xiao Lu
    • Wei Chen
    • Gui‑Hong Xiao
    • Yijin Zhang
    • Rongbin Yu
    • Jianan Li
  • View Affiliations

  • Published online on: May 17, 2018     https://doi.org/10.3892/etm.2018.6175
  • Pages: 260-264
  • Copyright: © Gao et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Effects of a 12-week physiological ischemic training (PIT) programme on safety of training and quality of life (QOL) in patients with coronary heart disease (CHD) complicated with heart failure were evaluated. A total of 30 patients with CHD complicated with heart failure were randomized to either an intervention group (n=15) or to controls (n=15) after baseline testing. A 12‑week, 5 times a week, maximum subjective force group PIT was conducted. Safety of the training was measured with ECG and heart rate and blood pressure, QOL was measured using the Minnesota Living with Heart Failure Questionnaire (MLHFQ) and vascular endothelial growth factor (VEGF) was measured with peripheral blood. VEGF and MLHFQ were improved in the intervention group. The finding of the study shows PIT is safe to patients with CHD complicated with heart failure by improving VEGF of peripheral blood and QOL.
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July-2018
Volume 16 Issue 1

Print ISSN: 1792-0981
Online ISSN:1792-1015

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Spandidos Publications style
Gao M, Lu X, Chen W, Xiao GH, Zhang Y, Yu R and Li J: Randomized clinical trial of physiological ischemic training for patients with coronary heart disease complicated with heart failure: Safety of training, VEGF of peripheral blood and quality of life. Exp Ther Med 16: 260-264, 2018
APA
Gao, M., Lu, X., Chen, W., Xiao, G., Zhang, Y., Yu, R., & Li, J. (2018). Randomized clinical trial of physiological ischemic training for patients with coronary heart disease complicated with heart failure: Safety of training, VEGF of peripheral blood and quality of life. Experimental and Therapeutic Medicine, 16, 260-264. https://doi.org/10.3892/etm.2018.6175
MLA
Gao, M., Lu, X., Chen, W., Xiao, G., Zhang, Y., Yu, R., Li, J."Randomized clinical trial of physiological ischemic training for patients with coronary heart disease complicated with heart failure: Safety of training, VEGF of peripheral blood and quality of life". Experimental and Therapeutic Medicine 16.1 (2018): 260-264.
Chicago
Gao, M., Lu, X., Chen, W., Xiao, G., Zhang, Y., Yu, R., Li, J."Randomized clinical trial of physiological ischemic training for patients with coronary heart disease complicated with heart failure: Safety of training, VEGF of peripheral blood and quality of life". Experimental and Therapeutic Medicine 16, no. 1 (2018): 260-264. https://doi.org/10.3892/etm.2018.6175