Open Access

Evaluation of the predictive value of high sensitivity C-reactive protein in pregnancy-induced hypertension syndrome

  • Authors:
    • Hang Chen
    • Jun Zhang
    • Fang Qin
    • Xinyun Chen
    • Xiaojing Jiang
  • View Affiliations

  • Published online on: May 31, 2018     https://doi.org/10.3892/etm.2018.6246
  • Pages: 619-622
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Abstract

Relationship between serum high sensitive C-reactive protein (hs-CRP) and pregnancy-induced hypertension syndrome (PIH) was investigated. One hundred and twenty patients with PIH treated in the First People's Hospital of Chengdu (60 cases of mild preeclampsia, 60 cases of severe preeclampsia) were enrolled in the study. The control group included 60 women with normal singleton pregnancy. Serum hs-CRP and microalbuminuria (mALB) levels were measured by an AU5800 automatic biochemical analyzer (Beckerman Coulter), and the risk factors were analyzed by ROC curve analysis. Patients with PIH had higher levels of serum hs-CRP and mALB than the control group (P<0.01). Serum hs-CRP and mALB levels in the severe preeclampsia group were significantly higher than those in the mild preeclampsia group (P<0.05). ROC curve analysis showed that hs-CRP was a factor of high-risk. Area under the curve was 0.943, and the 95% confidence interval was 0.848-0.974. Detection of serum hs-CRP in patients with PIH can provide references for the prediction of the severity of the disease, and higher level of hs-CRP indicates worse condition.
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August-2018
Volume 16 Issue 2

Print ISSN: 1792-0981
Online ISSN:1792-1015

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Spandidos Publications style
Chen H, Zhang J, Qin F, Chen X and Jiang X: Evaluation of the predictive value of high sensitivity C-reactive protein in pregnancy-induced hypertension syndrome. Exp Ther Med 16: 619-622, 2018
APA
Chen, H., Zhang, J., Qin, F., Chen, X., & Jiang, X. (2018). Evaluation of the predictive value of high sensitivity C-reactive protein in pregnancy-induced hypertension syndrome. Experimental and Therapeutic Medicine, 16, 619-622. https://doi.org/10.3892/etm.2018.6246
MLA
Chen, H., Zhang, J., Qin, F., Chen, X., Jiang, X."Evaluation of the predictive value of high sensitivity C-reactive protein in pregnancy-induced hypertension syndrome". Experimental and Therapeutic Medicine 16.2 (2018): 619-622.
Chicago
Chen, H., Zhang, J., Qin, F., Chen, X., Jiang, X."Evaluation of the predictive value of high sensitivity C-reactive protein in pregnancy-induced hypertension syndrome". Experimental and Therapeutic Medicine 16, no. 2 (2018): 619-622. https://doi.org/10.3892/etm.2018.6246