Open Access

Extensive bone metastases as the initial symptom of papillary thyroid microcarcinoma: A case report

  • Authors:
    • Wei Zheng
    • Jian Tan
    • Guizhi Zhang
  • View Affiliations

  • Published online on: April 14, 2015     https://doi.org/10.3892/etm.2015.2423
  • Pages: 2104-2108
  • Copyright: © Zheng et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

A 53-year-old female patient presented with lumbar and pelvic pain. The 18F-fluorodeoxyglucose (18F-FDG) positron emission tomography/computed tomography scintigraphy showed extensive bone destruction with hypermetabolic osteolysis, with increased 18F‑FDG uptake. The histological examination of the pubic bone lesion revealed a metastatic tumor. Neither chemotherapy nor radiotherapy could control the condition. More than a year later, the patient underwent a total thyroidectomy with cervical lymph node clearance. The histological examination revealed a papillary thyroid microcarcinoma (PTMC) in the left lobe with capsular invasion. 131I treatment with thyroid hormone withdrawal followed. The 131I whole‑body scintigraphy showed extensive uptake in the basic thyroid deposits, most bones and both lungs. Three months after the 131I treatment, the patient succumbed to cachexia. The present case indicated that not all PTMCs have excellent prognosis and that, despite being rare, clinically significant metastases can arise from a PTMC.
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June-2015
Volume 9 Issue 6

Print ISSN: 1792-0981
Online ISSN:1792-1015

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Spandidos Publications style
Zheng W, Tan J and Zhang G: Extensive bone metastases as the initial symptom of papillary thyroid microcarcinoma: A case report. Exp Ther Med 9: 2104-2108, 2015
APA
Zheng, W., Tan, J., & Zhang, G. (2015). Extensive bone metastases as the initial symptom of papillary thyroid microcarcinoma: A case report. Experimental and Therapeutic Medicine, 9, 2104-2108. https://doi.org/10.3892/etm.2015.2423
MLA
Zheng, W., Tan, J., Zhang, G."Extensive bone metastases as the initial symptom of papillary thyroid microcarcinoma: A case report". Experimental and Therapeutic Medicine 9.6 (2015): 2104-2108.
Chicago
Zheng, W., Tan, J., Zhang, G."Extensive bone metastases as the initial symptom of papillary thyroid microcarcinoma: A case report". Experimental and Therapeutic Medicine 9, no. 6 (2015): 2104-2108. https://doi.org/10.3892/etm.2015.2423