Hepatoid adenocarcinoma of the stomach: A case report and literature review

  • Authors:
    • Xiao-Mei Liu
    • Gui-Qiu Chen
    • Shun-Li Li
    • Tian-Shu Zai
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  • Published online on: March 30, 2015     https://doi.org/10.3892/etm.2015.2393
  • Pages: 2133-2136
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Abstract

Hepatoid adenocarcinoma (HAC) is a rare form of gastric cancer that has unique clinicopathological features and an extremely poor prognosis. The present case report describes a patient who was referred to the No. 461 Hospital of PLA (Changchun, China) due to nausea and occasional vomiting of acid/water. The patient was diagnosed with gastric signet‑ring cell carcinoma and surgery was recommended. A total gastrectomy was performed on the operable lesion. Histopathological analysis revealed that the tumors exhibited two pathological changes: HAC and signet‑ring cell carcinoma differentiation. Furthermore, the tumor cells were immunohistochemically positive for α-fetoprotein, cytokeratin low/high molecular weight, Cam5.2, cytokeratin 7, p53, epithelial membrane antigen and carcinoembryonic antigen. Previous studies and our experience have suggested that HAC is an aggressive type of adenocarcinoma; however, radical surgery and chemotherapy may positively impact clinical outcomes.
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June-2015
Volume 9 Issue 6

Print ISSN: 1792-0981
Online ISSN:1792-1015

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Spandidos Publications style
Liu X, Chen G, Li S and Zai T: Hepatoid adenocarcinoma of the stomach: A case report and literature review. Exp Ther Med 9: 2133-2136, 2015
APA
Liu, X., Chen, G., Li, S., & Zai, T. (2015). Hepatoid adenocarcinoma of the stomach: A case report and literature review. Experimental and Therapeutic Medicine, 9, 2133-2136. https://doi.org/10.3892/etm.2015.2393
MLA
Liu, X., Chen, G., Li, S., Zai, T."Hepatoid adenocarcinoma of the stomach: A case report and literature review". Experimental and Therapeutic Medicine 9.6 (2015): 2133-2136.
Chicago
Liu, X., Chen, G., Li, S., Zai, T."Hepatoid adenocarcinoma of the stomach: A case report and literature review". Experimental and Therapeutic Medicine 9, no. 6 (2015): 2133-2136. https://doi.org/10.3892/etm.2015.2393