Identification of SNPs in human gamma aminobutyric acid A receptor γ2 gene

  • Authors:
    • Zheng Tan
    • Songshan Jiang
    • Zhixin Lin
    • Bifeng Zhang
    • Jun Yu
    • Guoying Feng
    • Lin He
  • View Affiliations

  • Published online on: August 1, 2001     https://doi.org/10.3892/ijmm.8.2.205
  • Pages: 205-209
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Abstract

Gamma aminobutyric acid (GABA) is a major inhibitory neurotransmitter. Because of its importance and diverse functions, studies of single nucleotide polymorphisms in the GABA receptor genes are of great significance, which may produce useful molecular markers for genetic analysis of neurological disease, and possibly lead to the discovery of pathogenic mutations. We identified eleven SNPs in the entire exon regions, immediate intron regions and promoter region of human GABA receptor γ2 gene by direct sequencing. In this discovery, 2 non-synonymous cSNPs and 1 splicing variant are found.

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August 2001
Volume 8 Issue 2

Print ISSN: 1107-3756
Online ISSN:1791-244X

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Spandidos Publications style
Tan Z, Jiang S, Lin Z, Zhang B, Yu J, Feng G and He L: Identification of SNPs in human gamma aminobutyric acid A receptor γ2 gene. Int J Mol Med 8: 205-209, 2001
APA
Tan, Z., Jiang, S., Lin, Z., Zhang, B., Yu, J., Feng, G., & He, L. (2001). Identification of SNPs in human gamma aminobutyric acid A receptor γ2 gene. International Journal of Molecular Medicine, 8, 205-209. https://doi.org/10.3892/ijmm.8.2.205
MLA
Tan, Z., Jiang, S., Lin, Z., Zhang, B., Yu, J., Feng, G., He, L."Identification of SNPs in human gamma aminobutyric acid A receptor γ2 gene". International Journal of Molecular Medicine 8.2 (2001): 205-209.
Chicago
Tan, Z., Jiang, S., Lin, Z., Zhang, B., Yu, J., Feng, G., He, L."Identification of SNPs in human gamma aminobutyric acid A receptor γ2 gene". International Journal of Molecular Medicine 8, no. 2 (2001): 205-209. https://doi.org/10.3892/ijmm.8.2.205