Early Online

Metabolic changes associated with papillary thyroid carcinoma: A nuclear magnetic resonance-based metabolomics study

Yanyun Li, Minjian Chen, Cuiping Liu, Yankai Xia, Bo Xu, Yanhui Hu, Ting Chen, Meiping Shen, Wei Tang

Published online on: February 16, 2018

Euphorbia supina extract results in inhibition of high‑fat‑diet‑induced obesity in mice

Sarmila Nepali, Do‑Kuk Kim, Hoon‑Yeon Lee, Hyeon‑Hui Ki, Bo‑Ram Kim, Sung‑Woo Hwang, Min Park, Dae‑Ki Kim, Young‑Mi Lee

Published online on: February 16, 2018

Exosomes derived from human umbilical cord mesenchymal stem cells improve myocardial repair via upregulation of Smad7

Xin‑Long Wang, Yuan‑Yuan Zhao, Li Sun, Yu Shi, Zhu‑Qian Li, Xiang‑Dong Zhao, Chang‑Gen Xu, Hong‑Ge Ji, Mei Wang, Wen‑Rong Xu, Wei Zhu

Published online on: February 16, 2018
Open Access

AMP-activated protein kinase stimulates osteoblast differentiation and mineralization through autophagy induction

Yi Li, Jiajia Su, Wenchao Sun, Lin Cai, Zhouming Deng

Published online on: February 16, 2018
Open Access

LicA induces autophagy through ULK1/Atg13 and ROS pathway in human hepatocellular carcinoma cells

Qiang Niu, Wei Zhao, Jin Wang, Chunming Li, Tao Yan, Wei Lv, Guojing Wang, Weihong Duan, Tao Zhang, Kunnan Wang, Dinghua Zhou

Published online on: February 16, 2018
Open Access

Human umbilical cord mesenchymal stem cells inhibit proliferation of hepatic stellate cells in vitro

Li-Ting Zhang, Xue-Bin Peng, Xue-Qin Fang, Jun-Feng Li, Hong Chen, Xiao-Rong Mao

Published online on: February 16, 2018
Open Access

Early intervention with mesenchymal stem cells prevents nephropathy in diabetic rats by ameliorating the inflammatory microenvironment

Yuanmin Li, Jingping Liu, Guangneng Liao, Jie Zhang, Younan Chen, Lan Li, Li Li, Fang Liu, Bo Chen, Gang Guo, Chengshi Wang, Lichuan Yang, Jingqiu Cheng, Yangrong Lu

Published online on: February 16, 2018
Open Access

The antitumor activity screening of chemical constituents from Camellia nitidissima Chi

Xiaoying Hou, Hongzhi Du, Rui Yang, Jing Qi, Yue Huang, Shuyun Feng, Yao Wu, Sensen Lin, Zhixin Liu, Ai-Qun Jia, Shengtao Yuan, Li Sun

Published online on: February 16, 2018
Open Access

Sitagliptin ameliorates diabetic nephropathy by blocking TGF-β1/Smad signaling pathway

Dongdong Wang, Guanying Zhang, Xiao Chen, Tong Wei, Chenxu Liu, Chun Chen, Yinhan Gong, Qunli Wei

Published online on: February 16, 2018

Fingerprint analysis and pharmacological evaluation of Ailanthus altissima

Qiaoyan He, Huimin Xiao, Jie Li, Yang Liu, Min Jia, Fang Wang, Ya Zhang, Wen Wang, Siwang Wang

Published online on: February 14, 2018

BAG3 promotes the phenotypic transformation of primary rat vascular smooth muscle cells via TRAIL

Yao Fu, Ye Chang, Shuang Chen, Yuan Li, Yintao Chen, Guozhe Sun, Shasha Yu, Ning Ye, Chao Li, Yingxian Sun

Published online on: February 14, 2018
Open Access

Rhein protects against cerebral ischemic‑/reperfusion‑induced oxidative stress and apoptosis in rats

Qipeng Zhao, Xiaobo Wang, Ailing Chen, Xiuli Cheng, Guoxin Zhang, Jianmin Sun, Yunsheng Zhao, Yu Huang, Yafei Zhu

Published online on: February 13, 2018
Open Access

Decreased hyperpolarization-activated cyclic nucleotide-gated channels are involved in bladder dysfunction associated with spinal cord injury

Qian Liu, Chao Wu, Shengquan Huang, Qingjian Wu, Tao Zhou, Xiaobing Liu, Xin Liu, Xiaoyan Hu, Longkun Li

Published online on: February 13, 2018

Cav 1.2 and Cav 2.2 expression is regulated by different endogenous ghrelin levels in pancreatic acinar cells during acute pancreatitis

Jie Zhou, Mengbin Qin, Huilin Wang, Jiaping He, Hongzong Fu, Huirong Shi, Zhihai Liang, Guodu Tang

Published online on: February 13, 2018
Open Access

Tracking of transplanted human umbilical cord-derived mesenchymal stem cells labeled with fluorescent probe in a mouse model of acute lung injury

Genglong Liu, Haijin Lv, Yuling An, Xuxia Wei, Xiaomeng Yi, Huimin Yi

Published online on: February 13, 2018
Open Access

Iron limitation promotes the atrophy of skeletal myocytes, whereas iron supplementation prevents this process in the hypoxic conditions

Kamil Kobak, Monika Kasztura, Magdalena Dziegala, Jacek Bania, Violetta Kapuśniak, Waldemar Banasiak, Piotr Ponikowski, Ewa A. Jankowska

Published online on: February 12, 2018

RP105 protects PC12 cells from oxygen‑glucose deprivation/reoxygenation injury via activation of the PI3K/AKT signaling pathway

Yanpeng Sun, Lu Liu, Jiang Yuan, Qiang Sun, Na Wang, Yunfu Wang

Published online on: February 12, 2018

Anti‑apoptotic effects of glycosaminoglycans via inhibition of ERK/AP‑1 signaling in TNF‑α‑stimulated human dermal fibroblasts

Jungtae Na, Dong‑Ho Bak, Song I Im, Hyangtae Choi, Jung Hyun Hwang, Su Yeon Kong, Yeon A No, Yonghee Lee, Beom Joon Kim

Published online on: February 12, 2018
Open Access

Seawater inhalation induces acute lung injury via ROS generation and the endoplasmic reticulum stress pathway

Peng‑Cheng Li, Bo‑Rong Wang, Cong‑Cong Li, Xi Lu, Wei‑Sheng Qian, Yu‑Juan Li, Fa‑Guang Jin, De‑Guang Mu

Published online on: February 12, 2018
Open Access

microRNA expression profiles of scar and normal tissue from patients with posterior urethral stricture caused by pelvic fracture urethral distraction defects

Kaile Zhang, Jun Chen, Dongliang Zhang, Lin Wang, Weixin Zhao, David Yun-Te Lin, Rong Chen, Hong Xie, Xiaoyong Hu, Xiaolan Fang, Qiang Fu

Published online on: February 12, 2018

UVB induces apoptosis via downregulation of CALML3-dependent JNK1/2 and ERK1/2 pathways in cataract

Yin Jia, Qin Qin, Chao‑Ping Fang, Wei Shen, Ting‑Ting Sun, Yuan‑Lan Huang, Wen‑Jie Li, An‑Mei Deng

Published online on: February 9, 2018

Madecassoside activates anti‑neuroinflammatory mechanisms by inhibiting lipopolysaccharide‑induced microglial inflammation

Andrew Octavian Sasmita, Anna Pick Kiong Ling, Kenny Gah Leong Voon, Rhun Yian Koh, Ying Pei Wong

Published online on: February 9, 2018
Open Access

The interplay of BMP4 and IL‑7 regulates the apoptosis of intestinal intraepithelial lymphocytes under conditions of ischemia̸reperfusion

Binyu Luo, Kang Chen, Qi Feng, Weidong Xiao, Dan Ma, Hua Yang, Chaojun Zhang

Published online on: February 9, 2018

The expression and activation of sex steroid receptors in the preeclamptic placenta

Mee‑Na Park, Kyung‑Hee Park, Jae‑Eon Lee, Ye Young Shin, Sung‑Min An, Seong Soo Kang, Wan‑Seob Cho, Beum‑Soo An, Seung Chul Kim

Published online on: February 8, 2018

Concomitant modulation of PTEN and Livin in gastric cancer treatment

Chun‑Lin Zhao, Sheng‑Na Han, Zhi‑Ju Wang, Shu‑Hui Wang, Guo‑Qiang Zhao, Xie‑Fu Zhang, Jia‑Xiang Wang

Published online on: February 8, 2018
Open Access

LMO3 promotes gastric cancer cell invasion and proliferation through Akt-mTOR and Akt-GSK3β signaling

Yan-Song Qiu, Ning-Ning Jiang, Yan Zhou, Kuai-Yun Yu, Hong-Yan Gong, Guang-Jun Liao

Published online on: February 8, 2018

α‑lipoic acid can greatly alleviate the toxic effect of AGES on SH‑SY5Y cells

Guifen Niu, Jianfei Guo, Yaqiang Tian, Kexiang Zhao, Jian Li, Qian Xiao

Published online on: February 8, 2018
Open Access

Experimental study on the neurotoxic effect of β-amyloid on the cytoskeleton of PC12 cells

Lai Wang, Jingjing Cao, Zhenyu Shi, Wenjuan Fan, Hongliang Liu, Jinbo Deng, Jiexin Deng

Published online on: February 7, 2018

Homeobox protein MSX1 inhibits the growth and metastasis of breast cancer cells and is frequently silenced by promoter methylation

Yujuan Yue, Ying Yuan, Lili Li, Jiangxia Fan, Chen Li, Weiyan Peng, Guosheng Ren

Published online on: February 7, 2018

Ferroptosis is associated with oxygen-glucose deprivation/reoxygenation-induced Sertoli cell death

Li Li, Yu Hao, Yu Zhao, Huijuan Wang, Xiujun Zhao, Yan Jiang, Fulu Gao

Published online on: February 7, 2018

Changed immune and miRNA response in RAW264.7 cells infected with cell wall deficient mycobacterium tuberculosis

Zhengjun Yi, Kunshan Gao, Ruifang Li, Yurong Fu

Published online on: February 7, 2018
Open Access

Novel iridium (III)‑derived organometallic compound for the inhibition of human platelet activation

Kou‑Gi  Shyu, Marappan  Velusamy, Chih‑Wei  Hsia, Chih‑Hao  Yang, Chih‑Hsuan  Hsia, Duen‑Suey  Chou, Thanasekaran  Jayakumar, Joen‑Rong  Sheu, Jiun‑Yi  Li

Published online on: February 7, 2018

L‑histidine augments the oxidative damage against Gram‑negative bacteria by hydrogen peroxide

Tamiko Nagao, Haruyuki Nakayama‑Imaohji, Miad Elahi, Ayano Tada, Emika Toyonaga, Hisashi Yamasaki, Katsuichiro Okazaki, Hirokazu Miyoshi, Koichiro Tsuchiya, Tomomi Kuwahara

Published online on: February 7, 2018
Open Access

Antiproliferative effects of the CDK6 inhibitor PD0332991 and its effect on signaling networks in gastric cancer cells

Daguang Wang, Yabin Sun, Wei Li, Fei Ye, Yang Zhang, Yuchen Guo, David Y. Zhang, Jian Suo

Published online on: February 6, 2018
Open Access

Resveratrol protects against sodium nitroprusside induced nucleus pulposus cell apoptosis by scavenging ROS

Kang Li, Yan Li, Jie Mi, Lu Mao, Xiuguo Han, Jie Zhao

Published online on: February 6, 2018
Open Access

Hypoxia induces pulmonary arterial fibroblast proliferation, migration, differentiation and vascular remodeling via the PI3K/Akt/p70S6K signaling pathway

Xiaoyu Chai, Dan Sun, Qian Han, Liang Yi, Yanping Wu, Xinmin Liu

Published online on: February 6, 2018

Downregulation of secreted clusterin potentiates the lethality of sorafenib in hepatocellular carcinoma in association with the inhibition of ERK1/2 signals

Jingtao Zhong, Xiaoming Yu, Xiaofeng Dong, Hong Lu, Wuyuan Zhou, Lei Li, Zhongchao Li, Pengfei Sun, Xuetao Shi

Published online on: February 6, 2018
Open Access

Methylation-induced downregulation and tumor-suppressive role of microRNA-98 in glioma through targeting Sal-like protein 4

Zhiwei Xia, Dongxu Qiu, Jun Deng, Xiao Jiao, Ronghe Yang, Zhongyi Sun, Xin Wan, Jing Li

Published online on: February 6, 2018
Open Access

Amelioration of inflammatory responses by Socheongryong-Tang, a traditional herbal medicine, in RAW 264.7 cells and rats

Sang Mi Park, Tae Hoon Lee, Rongjie Zhao, Youn Sook Kim, Ji Yun Jung, Chung A. Park, Kyung Hwan Jegal, Sae Kwang Ku, Jae Kwang Kim, Chul Won Lee, Young Woo Kim, Il Je Cho, Won G. An, Sang Chan Kim

Published online on: February 6, 2018
Open Access

Necrostatin-1 protects C2C12 myotubes from CoCl2-induced hypoxia

Rui Chen, Jiehua Xu, Yanling She, Ting Jiang, Shanyao Zhou, Huacai Shi, Cheng Li

Published online on: February 6, 2018
Open Access

Protective effect of adenovirus-mediated erythropoietin expression on the spiral ganglion neurons in the rat inner ear

Cheng Zhong, Zhendong Jiang, Qiang Guo, Xueyuan Zhang

Published online on: February 5, 2018

Mitochondrial protective mechanism of simvastatin protects against amyloid β peptide-induced injury in SH-SY5Y cells

Yunzi Li, Qian Liu, Jing Sun, Jin Wang, Xinfeng Liu, Jing Gao

Published online on: February 5, 2018
Open Access

Long noncoding RNA ENSRNOG00000037522 is involved in the podocyte epithelial‑mesenchymal transition in diabetic rats

Li Ling, Zhen Tan, Changning Zhang, Shuyan Gui, Yuanyuan Hu, Libo Chen

Published online on: February 5, 2018

The effects of TRAF6 on proliferation, apoptosis and invasion in osteosarcoma are regulated by miR-124

Qingbing Meng, Wensheng Zhang, Xingli Xu, Jian Li, Hongxin Mu, Xiaolan Liu, Ling Qin, Xiaoqi Zhu, Minqian Zheng

Published online on: February 5, 2018
Open Access

Identification of novel hyper- or hypomethylated CpG sites and genes associated with atherosclerotic plaque using an epigenome-wide association study

Yoshiji Yamada, Hideki Horibe, Mitsutoshi Oguri, Jun Sakuma, Ichiro Takeuchi, Yoshiki Yasukochi, Kimihiko Kato, Motoji Sawabe

Published online on: February 2, 2018
Open Access

Transplantation of allogenic nucleus pulposus cells attenuates intervertebral disc degeneration by inhibiting apoptosis and increasing migration

Weiheng Wang, Guoying Deng, Yuanyuan Qiu, Xiaodong Huang, Yanhai Xi, Jiangming Yu, Xiangqun Yang, Xiaojian Ye

Published online on: February 2, 2018
Open Access

Microenvironment‑driven resistance to B‑Raf inhibition in a melanoma patient is accompanied by broad changes of gene methylation and expression in distal fibroblasts

Ondřej Kodet, Barbora Dvořánková, Běla Bendlová, Vlasta Sýkorová, Ivana Krajsová, Jiří Štork, Jan Kučera, Pavol Szabo, Hynek Strnad, Michal Kolář, Čestmír Vlček, Karel Smetana, Lukáš Lacina

Published online on: February 1, 2018
Open Access

Stage‑dependent changes of β2‑adrenergic receptor signaling in right ventricular remodeling in monocrotaline‑induced pulmonary arterial hypertension

Fengjiao Sun, Zhiqiang Lu, Yidan Zhang, Shihan Geng, Mengxi Xu, Liman Xu, Yingying Huang, Pengwei Zhuang, Yanjun Zhang

Published online on: February 1, 2018
Open Access

Structural characterization, immune regulation and antioxidant activity of a new heteropolysaccharide from Cantharellus cibarius Fr.

Daqun Zhao, Xiang Ding, Yiling Hou, Wanru Hou, Lu Liu, Ting Xu, Danni Yang

Published online on: February 1, 2018
Open Access

BCL6B suppresses proliferation and migration of colorectal carcinoma cells through inhibition of the PI3K/AKT signaling pathway

Yue Gu, Aifang Li, Hui Sun, Xueru Li, He Zha, Jiali Zhao, Jiaqing Xie, Zongyue Zeng, Lan Zhou

Published online on: February 1, 2018

Role of microRNAs in progenitor cell commitment and osteogenic differentiation in health and disease (Review)

Maria Teresa Valenti, Luca Dalle Carbonare, Monica Mottes

Published online on: February 1, 2018
Journal Cover

Print ISSN: 1107-3756
Online ISSN: 1791-244X

2016 Impact Factor: 2.341
Ranked #21/128 Medicine Research and Experimental
(total number of cites)

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