Characterisation of a collecting duct carcinoma by cytogenetic analysis and comparative genomic hybridisation.

  • Authors:
    • I Verdorfer
    • Z Culig
    • A Hobisch
    • G Bartsch
    • A Hittmair
    • H C Duba
    • M Erdel
  • View Affiliations

  • Published online on: September 1, 1998     https://doi.org/10.3892/ijo.13.3.461
  • Pages: 461-465
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Abstract

Collecting duct carcinoma (CDC) is a rare variant of carcinoma of the kidney with aggressive behaviour. CDC arise from the epithelium of the ducts of Bellini in the distal nephron. A CDC in a 53-year old male patient is characterised both by cytogenetic analysis and comparative genomic hybridisation (CGH). The cytogenetic analysis shows a biclonal karyotype 47,XY,+3[2]/40-44,XY,-12[3], -22[4][cp5]/46,XY[42]. Loss of DNA sequences detected by CGH involves chromosome 1, 2, 9, 11 and 18. Gain of DNA sequences affect chromosome 16 and 20. The characterisation of a CDC in this study represents an additional contribution to the poorly explored CDC.

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Sep 1998
Volume 13 Issue 3

Print ISSN: 1019-6439
Online ISSN:1791-2423

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Spandidos Publications style
Verdorfer I, Culig Z, Hobisch A, Bartsch G, Hittmair A, Duba H and Erdel M: Characterisation of a collecting duct carcinoma by cytogenetic analysis and comparative genomic hybridisation.. Int J Oncol 13: 461-465, 1998
APA
Verdorfer, I., Culig, Z., Hobisch, A., Bartsch, G., Hittmair, A., Duba, H., & Erdel, M. (1998). Characterisation of a collecting duct carcinoma by cytogenetic analysis and comparative genomic hybridisation.. International Journal of Oncology, 13, 461-465. https://doi.org/10.3892/ijo.13.3.461
MLA
Verdorfer, I., Culig, Z., Hobisch, A., Bartsch, G., Hittmair, A., Duba, H., Erdel, M."Characterisation of a collecting duct carcinoma by cytogenetic analysis and comparative genomic hybridisation.". International Journal of Oncology 13.3 (1998): 461-465.
Chicago
Verdorfer, I., Culig, Z., Hobisch, A., Bartsch, G., Hittmair, A., Duba, H., Erdel, M."Characterisation of a collecting duct carcinoma by cytogenetic analysis and comparative genomic hybridisation.". International Journal of Oncology 13, no. 3 (1998): 461-465. https://doi.org/10.3892/ijo.13.3.461